A Convenient Synthesis of 3-(1-Aminoalkyl)quinolin-2(1 H )-one Derivatives
| العنوان: | A Convenient Synthesis of 3-(1-Aminoalkyl)quinolin-2(1 H )-one Derivatives |
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| المؤلفون: | Kazutaka Hayashi, Osamu Morikawa, Kazuhiro Kobayashi, Hisatoshi Konishi, Masaaki Mano, Miyuki Tanmatsu, Yuhei Fuchimoto |
| المصدر: | Synthesis. 2005:2673-2676 |
| بيانات النشر: | Georg Thieme Verlag KG, 2005. |
| سنة النشر: | 2005 |
| مصطلحات موضوعية: | chemistry.chemical_classification, Double bond, Chemistry, Magnesium, Organic Chemistry, chemistry.chemical_element, Medicinal chemistry, Catalysis, Acetic anhydride, chemistry.chemical_compound, Pyridine, Urea derivatives, Alkyl, Carbanion |
| الوصف: | Treatment of magnesium enolates of 1-methyl-3,4-dihydroquinolin-2(1H)-ones with nitriles, followed by N-acetylation of the resulting vinylogous urea derivatives with acetic anhydride/pyridine and double bond migration with l,8-diazabicyclo[5.3.0]undec-7-ene, affords 3-[l-(acetylamino)alkyl]-l-methylquinolin-2(1H)-one derivatives in reasonable overall yields. |
| تدمد: | 1437-210X 0039-7881 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::248c499c71b70cd67feacafe88a1ebecTest https://doi.org/10.1055/s-2005-872086Test |
| رقم الانضمام: | edsair.doi...........248c499c71b70cd67feacafe88a1ebec |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1437210X 00397881 |
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