Zur topischen Anwendung von Oxybutyninhydrochlorid bei Frauen mit Urge-Inkontinenz
| العنوان: | Zur topischen Anwendung von Oxybutyninhydrochlorid bei Frauen mit Urge-Inkontinenz |
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| المؤلفون: | H. Enzelsberger, F. Mittermayer, Hanns Helmer, Ch. Kurz |
| المصدر: | Geburtshilfe und Frauenheilkunde. 55:240-243 |
| بيانات النشر: | Georg Thieme Verlag KG, 1995. |
| سنة النشر: | 1995 |
| مصطلحات موضوعية: | medicine.drug_class, business.industry, media_common.quotation_subject, Obstetrics and Gynecology, Urinary incontinence, Bladder capacity, Pollakisuria, Placebo, Urination, Oxybutynin Chloride, Anesthesia, Maternity and Midwifery, medicine, Anticholinergic, medicine.symptom, Oxybutynin, business, medicine.drug, media_common |
| الوصف: | Detrusor instability is the second most common cause of femal urinary incontinence. Oxybutynin chloride anticholinergic action with direct muscle-relaxant properties. 39 women with persistent-urgeincontinence participated in a pilot study of intravesical oxybutynin application. Patients received either 20 mg oxybutynin or placebo as 40 ml sterile sodium chloride solution administered intravesically over a period of 10 days. Urodynamic assessment as well as micturition protocols were performed before and after treatment. The intravesical oxybutynin-application was significantly better than the placebo application concerning reduction of pollakisuria and nycturia. Oxybutynin also increased bladder capacity more than in the placebo-treated group (p < 0.01) and provided an improvement of bladder compliance (p < 0.05). No local or systemic side effects were observed which would have immediately terminated the oxybutynin treatment. |
| تدمد: | 1438-8804 0016-5751 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::67f6117d2696fe859f62bda727adc4bfTest https://doi.org/10.1055/s-2007-1023310Test |
| رقم الانضمام: | edsair.doi...........67f6117d2696fe859f62bda727adc4bf |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14388804 00165751 |
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