التفاصيل البيبلوغرافية
| العنوان: |
Treatment patterns and outcomes among nontransplant newly diagnosed multiple myeloma patients in Spain. |
| المؤلفون: |
Hernández-Rivas, José-Ángel, Arnao, Mario, Arguiñano Pérez, José Maria, Rubio, Araceli, García, Esther Gónzalez, de Miguel, Dunia, Cherepanov, Dasha, Romanus, Dorothy, Verleger, Katharina, Johnson, Courtney, Corman, Shelby L, Grande, Marta, Persona, Ernesto Pérez |
| المصدر: |
Future Oncology; Aug2021, Vol. 17 Issue 26, p3465-3476, 12p |
| مصطلحات موضوعية: |
THERAPEUTIC use of protease inhibitors, SURVIVAL, COMBINATION drug therapy, PROGNOSIS, RETROSPECTIVE studies, IMMUNOLOGICAL adjuvants, ALKYLATING agents, DRUG therapy, MENTAL health surveys, RESEARCH funding, MULTIPLE myeloma, LONGITUDINAL method |
| مصطلحات جغرافية: |
SPAIN |
| مستخلص: |
Aim: To describe treatment patterns and outcomes in nontransplant newly diagnosed multiple myeloma (NDMM) patients in Spain. Methods: This retrospective study included two cohorts of NDMM patients diagnosed between 1 January 2012 to 31 December 2013 and 1 April 2016 to 31 March 2017. Results: Among 113 patients, proteasome inhibitor (PI) + alkylator combinations (49%) and PI-based regimens without an alkylator (30%) were the most common first-line (1L) therapies. Use of PI + immunomodulatory drug-based regimens increased between the cohorts; PI-based regimens without an alkylator/immunomodulatory drug decreased. Use of 1L oral regimens was low but increased over time; use of maintenance therapy was low across both periods. Median 1L duration of treatment was 6.9 months. Conclusion: Short 1L duration of treatment and low use of 1L oral regimens and maintenance therapy highlight unmet needs in NDMM. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
