دورية أكاديمية
Evaluation of acute administration of natural products with potential diuretic effects, in humans
| العنوان: | Evaluation of acute administration of natural products with potential diuretic effects, in humans |
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| المؤلفون: | Sandra M. R. Laranja, Cassia M. Bergamaschi, Nestor Schor |
| المصدر: | Memorias do Instituto Oswaldo Cruz, Vol 86, Pp 237-240 (1991) |
| بيانات النشر: | Fundação Oswaldo Cruz (FIOCRUZ), 1991. |
| سنة النشر: | 1991 |
| المجموعة: | LCC:Microbiology LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | Natural products, diuretics, Elephantopus scaber, Alpinia speciosa, Microbiology, QR1-502, Infectious and parasitic diseases, RC109-216 |
| الوصف: | In order to evaluate the potential diuretic effect of two natural products, Elephantopus scaber and Alpinia speciosa, a trial administration was carried out in ten healthy volunteers and the effects compared to the those of a placebo. The substances were given on different days, with a seven day interval between doses. The amount of substance administered to the subjects was five times the usual dose i.e. 7.5 g/100 ml and 0.8 g/100 ml respectively. The following parameters parameteres were measured: urinary and plasma sodium, potassium, uric acid, calcium, phosphate, urea, creatinine. The subjects were also examined clinically and total urinary volume was assessed. The only significant finding (p < 0.05) was a slight diuresis with Alpinia speciosa, which also lowered the diastolic (p < 0.05) and systolic (p < 0.01) blood pressures. No effect on electrolytes or renal function parameters was observed, and this probably excludes any renal tubular or glomerular effect from these substances. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0074-0276 1678-8060 |
| العلاقة: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761991000600053Test; https://doaj.org/toc/0074-0276Test; https://doaj.org/toc/1678-8060Test |
| DOI: | 10.1590/S0074-02761991000600053 |
| الوصول الحر: | https://doaj.org/article/64877ac386654c7c90a4ce7b7c0c4476Test |
| رقم الانضمام: | edsdoj.64877ac386654c7c90a4ce7b7c0c4476 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 00740276 16788060 |
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| DOI: | 10.1590/S0074-02761991000600053 |