Evaluation of Donor and Recipient Characteristics Involved in Descemet Stripping Automated Endothelial Keratoplasty Outcomes
| العنوان: | Evaluation of Donor and Recipient Characteristics Involved in Descemet Stripping Automated Endothelial Keratoplasty Outcomes |
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| المؤلفون: | Rosa Boccia, Michele Lanza, Adriano Ruggiero, Mario Bifani Sconocchia, Sandro Sbordone, Francesca Simonelli, Paolo Melillo |
| المساهمون: | Lanza, M., Boccia, R., Ruggiero, A., Melillo, P., Bifani Sconocchia, M., Simonelli, F., Sbordone, S. |
| المصدر: | Frontiers in Medicine Frontiers in Medicine, Vol 8 (2021) |
| بيانات النشر: | Frontiers Media SA, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Visual acuity, genetic structures, medicine.medical_treatment, Glaucoma, Ophthalmology, DSAEK complications, medicine, DSAEK, Corneal transplantation, Original Research, lcsh:R5-920, business.industry, Eye bank, Fuch's dystrophy, General Medicine, Cataract surgery, medicine.disease, eye diseases, corneal transplantation, Bullous keratopathy, Medicine, sense organs, Implant, bullous keratopathy, medicine.symptom, lcsh:Medicine (General), Complication, business, DSAEK complication |
| الوصف: | Aims: To evaluate both donor and recipient features involved in visual acuity restoring and complication insurgence in eyes that have undergone Descemet stripping automated endothelial keratoplasty (DSAEK).Methods: In this retrospective study, charts of 111 eyes of 96 patients (mean age 70.25 ± 8.58 years) that underwent DSAEK were evaluated. Only Fuch's Distrophy (FD) or Bullous Keratopathy (BK) due to cataract surgery eyes were included. A complete ophthalmic check with endothelial cell density (ECD) and central corneal thickness (CCT) measurement was performed before surgery and at 1, 3, 6, and 12 months follow-up. Each DSAEK was performed by the same well-trained surgeon; only pre-cut lenticules, provided by same Eye Bank, were implanted.Results: A total of 48 (43%) complications have been observed (most of them were 22 partial graft detachments and 17 IOP spikes). At the last follow-up (mean: 8.58 ± 4.09 months), a significant increase (p < 0.05) of best corrected visual acuity (BCVA) was detected. Overall mean BCVA of the eyes evaluated was 0.40 ± 0.43 LogMAR with BK eyes showing a significantly higher improvement (p < 0.05) compared to FD eyes. The only factor showing a significant correlation (p < 0.05) with visual acuity enhancement was the implant of a lenticule thinner than 100 μm. Recipient features significantly (p < 0.05) associated with complications observed after surgery were glaucoma and diabetes mellitus.Conclusion: The use of a graft thinner than 100 μm can provide better visual acuity recovery while recipients affected by glaucoma or diabetes mellitus are more prone to develop complications after surgery. |
| تدمد: | 2296-858X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b16415c9d20f9f468225d9b180d088cTest https://doi.org/10.3389/fmed.2021.605160Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....4b16415c9d20f9f468225d9b180d088c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 2296858X |
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