Modulation of host miRNAs by intracellular bacterial pathogens
| العنوان: | Modulation of host miRNAs by intracellular bacterial pathogens |
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| المؤلفون: | Kishore Das, Subramanian Dhandayuthapani, Omar Garnica |
| المصدر: | Frontiers in Cellular and Infection Microbiology, Vol 6 (2016) Frontiers in Cellular and Infection Microbiology |
| بيانات النشر: | Frontiers Media S.A., 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | 0301 basic medicine, Microbiology (medical), Cytoplasm, Listeria, Immunology, lcsh:QR1-502, Review, Biology, Microbiology, lcsh:Microbiology, Host-Parasite Interactions, Mycobacterium, 03 medical and health sciences, 0302 clinical medicine, Immune system, Bacterial Proteins, Salmonella, microRNA, Animals, Humans, Francisella, Gene, Bacteria, Cell growth, Intracellular parasite, Macrophages, regulation, Bacterial Infections, biology.organism_classification, Immunity, Innate, Cell biology, MicroRNAs, Metabolic pathway, 030104 developmental biology, Infectious Diseases, host, 030220 oncology & carcinogenesis, Metabolic Networks and Pathways, Intracellular |
| الوصف: | MicroRNAs (miRNAs) are short non-coding RNAs that regulate the expression of protein coding genes of viruses and eukaryotes at the post-transcriptional level. The eukaryotic genes regulated by miRNAs include those whose products are critical for biological processes such as cell proliferation, metabolic pathways, immune response, and development. It is now increasingly recognized that modulation of miRNAs associated with biological processes is one of the strategies adopted by bacterial pathogens to survive inside the host cells. In this review, we present an overview of the recent findings on alterations of miRNAs in the host cells by facultative intracellular bacterial pathogens. In addition, we discuss how the altered miRNAs help in the survival of these pathogens in the intracellular environment. |
| اللغة: | English |
| تدمد: | 2235-2988 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb0fa5344ba6f886f79d15c9daaf076Test http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00079/fullTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....adb0fa5344ba6f886f79d15c9daaf076 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22352988 |
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