Additional file 1 of Licorice extract inhibits growth of non-small cell lung cancer by down-regulating CDK4-Cyclin D1 complex and increasing CD8+ T cell infiltration
التفاصيل البيبلوغرافية
العنوان:
Additional file 1 of Licorice extract inhibits growth of non-small cell lung cancer by down-regulating CDK4-Cyclin D1 complex and increasing CD8+ T cell infiltration
Additional file 1. Table S1 Candidate targets for each active compound. Fig. S1 Additional file 1 Inhibition of Liquiritin on H1975 cells. Fig. S2 Typical HPLC chromatogram of licorice extract where: (1) Liquiritin, 2.28% (2) Liquiritigenin, 0.18% (3) Glycyrrhizin, 2.95% (4) Isoliquiritigenin, 0.035%. Fig. S3 Regulation of the CDK4-Cyclin D1/PD-L1 axis with GUF in A549 cells. Fig. S4 Correlation between CD8+ T cell infiltration and licorice targets in TCGA LUAD dataset and infiltration of CD8+ T cells caused by GUF in LLC mouse model.
