Additional file 1. Table S1. Homeostasis model assessment of insulin (HOMA-IR),TNF-α, IL-1β and IL-6 at the end of the trial. Table S2. Blood glucose concentrations during the oral glucose tolerance tests (OGTTs) following the treatment for 6 weeks. Table S3. Blood glucose concentrations during the oral glucose tolerance tests (OGTTs) following the treatment for 8 weeks. Table S4. Blood glucose concentrations during the oral glucose tolerance tests (OGTTs) following the treatment for 10 weeks. Tables S5 and S6 TLR mRNA relative expression pattern of skeletal muscle. Table S7 and the original western blots Effect of WEM treatment on protein expression TLR1, TLR2, and the downstream transcription factors' expression. Table S8. The gene expression of IRS1 and InsR affected by WEM in adipose tissue. Table S9 and the original western blots Protein expression of IRS1 and InsR influenced by WEM in adipose tissue of diabetic mice.