دورية أكاديمية
Autoimmune conditions and chronic infections in chronic lymphocytic leukemia patients at diagnosis are associated with unmutated IgVH genes
العنوان: | Autoimmune conditions and chronic infections in chronic lymphocytic leukemia patients at diagnosis are associated with unmutated IgVH genes |
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المؤلفون: | Katrina Vanura, Trang Le, Harald Esterbauer, Florentin Späth, Edit Porpaczy, Medhat Shehata, Karin Eigenberger, Alexander Hauswirth, Cathrin Skrabs, Elisabeth Krömer, Ilse Schwarzinger, Berthold Streubel, Christoph Steininger, Christa Fonatsch, Stephan Stilgenbauer, Oswald Wagner, Alexander Gaiger, Ulrich Jäger |
المصدر: | Haematologica, Vol 93, Iss 12 (2008) |
بيانات النشر: | Ferrata Storti Foundation, 2008. |
سنة النشر: | 2008 |
المجموعة: | LCC:Diseases of the blood and blood-forming organs |
مصطلحات موضوعية: | Diseases of the blood and blood-forming organs, RC633-647.5 |
الوصف: | Few data are available concerning the prevalence of autoimmune disease or chronic infections in chronic lymphocytic leukemia patients at diagnosis as well as their clinical outcome. We studied the frequency of such chronic conditions in relation to prognostic markers. A history of autoimmune disease or chronic infection was found in 21% of 186 chronic lymphocytic leukemia patients (12% in autoimmune diseases, 9% in chronic infections). Patients with a history of chronic stimulation were more likely to have unmutated IgVH genes (p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 0390-6078 1592-8721 |
العلاقة: | https://haematologica.org/article/view/5119Test; https://doaj.org/toc/0390-6078Test; https://doaj.org/toc/1592-8721Test |
DOI: | 10.3324/haematol.12955 |
الوصول الحر: | https://doaj.org/article/0eae39d85f604666bcce66e66db8b74bTest |
رقم الانضمام: | edsdoj.0eae39d85f604666bcce66e66db8b74b |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 03906078 15928721 |
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DOI: | 10.3324/haematol.12955 |