Standard practice and controversial issues in front-line therapy of acute promyelocytic leukemia
| العنوان: | Standard practice and controversial issues in front-line therapy of acute promyelocytic leukemia |
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| المؤلفون: | Miguel Sanz, Lo Coco, Francesco |
| المصدر: | HAEMATOLOGICA r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe instname Publons |
| بيانات النشر: | FERRATA STORTI FOUNDATION, 2005. |
| سنة النشر: | 2005 |
| مصطلحات موضوعية: | Adult, Promyelocytic, Male, Risk, Leukemia, Adolescent, Remission Induction, Antineoplastic Agents, Hematology, ALK1, Aged, Female, Humans, Leukemia, Promyelocytic, Acute, Middle Aged, Pregnancy, Recurrence, Acute, VEGF, angiogenesis, hereditary hemorrhagic telangiectasia (HHT), Settore MED/15 - Malattie del Sangue, TGF-beta 1 |
| الوصف: | In addition to choosing a state-of-the-art regimen including all-trans retinoic acid and anthracycline chemotherapy, modern management of acute promyelocytic leukemia (APL) implies the adoption of appropriate supportive measures, rapid establishment of an accurate genetic diagnosis, correct assessment of response to therapy and evaluation of the risk of disease recurrence by molecular monitoring. However, the general consensus about this overall strategy for APL treatment still leaves room for debate. In the present article, we review the current standard practice and controversial issues in the treatment of patients with newly diagnosed APL, including the management of special situations such as elderly patients, children and pregnant women. |
| تدمد: | 0390-6078 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0e50e317c4df337ebd0a57ababed7235Test https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=16148Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.pmid.dedup....0e50e317c4df337ebd0a57ababed7235 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 03906078 |
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