Effect of glutamine on the total antioxidant system of rats subjected to renal ischemia and reperfusion
| العنوان: | Effect of glutamine on the total antioxidant system of rats subjected to renal ischemia and reperfusion |
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| المؤلفون: | Erlon Côrtes, Alberto Bicudo Salomão, Marina Francine Munhoz, Valter Torezan Gouvêa Junior, José Eduardo Aguilar de Nascimento, Cervantes Caporossi |
| المصدر: | Acta Cirurgica Brasileira, Volume: 26, Issue: 6, Pages: 445-450, Published: DEC 2011 Acta Cirúrgica Brasileira v.26 n.6 2011 Acta Cirúrgica Brasileira Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) instacron:SBDPC |
| بيانات النشر: | FapUNIFESP (SciELO), 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Male, Glutamina, medicine.medical_specialty, Antioxidant, Free Radicals, Glutamine, medicine.medical_treatment, Biology, Kidney, Renal Artery Obstruction, Nephrectomy, Antioxidants, Superoxide dismutase, Random Allocation, Ischemia, Transplante de Rim, Internal medicine, medicine, Animals, Rats, Wistar, Lung, Kidney transplantation, Ratos, chemistry.chemical_classification, Glutathione Peroxidase, L-Lactate Dehydrogenase, Radicais Livres, Renal ischemia, Superoxide Dismutase, Glutathione peroxidase, Obstrução da Artéria Renal, Lung Injury, medicine.disease, Kidney Transplantation, Rats, Surgery, Isquemia, Endocrinology, medicine.anatomical_structure, chemistry, Creatinine, Reperfusion Injury, biology.protein, Biomarkers |
| الوصف: | PURPOSE: To evaluate the protective effects of glutamine administered before renal ischemia-reperfusion on plasma antioxidant protection, and lung and renal tissue injury. METHODS: 33 rats underwent right nephrectomy. On the eighth postoperative day, animals were randomized into three groups (n=11): glutamine, control and sham. Each group of animals received, by gavage, a particular diet for 7 days. On day 14 following nephrectomy, the animals were subjected to left renal ischemia-reperfusion. After this, blood samples were collected and the animals were killed. At necropsy the kidney and lung were removed for histology. RESULTS: The levels of total antioxidant capacity were higher in the glutamine group and control group compared with the sham group. The levels of glutathione peroxidase in both the sham and glutamine groups were higher when compared with the control group (p |
| وصف الملف: | text/html |
| تدمد: | 0102-8650 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fbb32e821ddcb7f201e0f8d381a43a3Test https://doi.org/10.1590/s0102-86502011000600007Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....4fbb32e821ddcb7f201e0f8d381a43a3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 01028650 |
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