المؤلفون: Martens, Marvin, Stierum, Rob, Schymanski, Emma, Evelo, Chris, Aalizadeh, Reza, Aladjov, Hristo, Arturi, Kasia, Audouze, Karine, Babica, Pavel, Berka, Karel, Bessems, Jos, Blaha, Ludek, Bolton, Evan, Cases, Montserrat, Damalas, Dimitrios, Dave, Kirtan, Dilger, Marco, Exner, Thomas, Geerke, Daan, Grafström, Roland, Gray, Alasdair, Hancock, John, Hollert, Henner, Jeliazkova, Nina, Jennen, Danyel, Jourdan, Fabien, Kahlem, Pascal, Klanova, Jana, Kleinjans, Jos, Kondic, Todor, Kone, Boï, Lynch, Iseult, Maran, Uko, Martinez Cuesta, Sergio, Ménager, Hervé, Neumann, Steffen, Nymark, Penny, Oberacher, Herbert, Ramirez, Noelia, Remy, Sylvie, Rocca-Serra, Philippe, Salek, Reza, Sallach, Brett, Sansone, Susanna-Assunta, Sanz, Ferran, Sarimveis, Haralambos, Sarntivijai, Sirarat, Schulze, Tobias, Slobodnik, Jaroslav, Spjuth, Ola, Tedds, Jonathan, Thomaidis, Nikolaos, Weber, Ralf, van Westen, Gerard, Wheelock, Craig, Williams, Antony, Witters, Hilda, Zdrazil, Barbara, Županič, Anže, Willighagen, Egon

المساهمون: Department of Bioinformatics, Maastricht University Medical Center (BiGCaT), The Netherlands Organisation for Applied Scientific Research (TNO), Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg Luxembourg, Maastricht Centre for Systems Biology, Maastricht University Medical Center (MaCSBio), National and Kapodistrian University of Athens (NKUA), Bulgarian Academy of Sciences (BAS), Swiss Federal Institute of Aquatic Science & Technology (EAWA), Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire (T3S - UMR_S 1124), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Research Centre for Toxic Compounds in the Environment Brno (RECETOX / MUNI), Faculty of Science Brno (SCI / MUNI), Masaryk University Brno (MUNI)-Masaryk University Brno (MUNI), Palacky University Olomouc, Flemish Institute for Technological Research (VITO), National Center for Biotechnology Information (NCBI), National Institutes of Health Bethesda, MD, USA (NIH), Chemotargets SL, GSFC University, Forschungs- und Beratungsinstitut Gefahrstoffe GmbH (FoBiG), Seven Past Nine, Vrije Universiteit Amsterdam Amsterdam (VU), Karolinska Institutet Stockholm, Misvik Biology, Heriot-Watt University Edinburgh (HWU), ELIXIR Hub Cambridge, Goethe University Frankfurt, Ideaconsult, Maastricht University Maastricht, ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), MetaboHUB-MetaToul, MetaboHUB-Génopole Toulouse Midi-Pyrénées Auzeville (GENOTOUL), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Faculté de Médecine, de pharmacie et d’Odonto-Stomatologie Bamako, Mali (FMPOS), Université de Bamako, University of Birmingham Birmingham, University of Tartu, AstraZeneca Cambridge, UK, Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Institut Français de Bioinformatique (IFB-CORE), Institut National de Recherche en Informatique et en Automatique (Inria)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Leibniz Institute of Plant Biochemistry (IPB), Innsbruck Medical University = Medizinische Universität Innsbruck (IMU), Universitat Rovira i Virgili, University of Oxford, Centre International de Recherche contre le Cancer - International Agency for Research on Cancer (CIRC - IARC), Organisation Mondiale de la Santé / World Health Organization Office Genève, Suisse (OMS / WHO), University of York York, UK, Universitat Pompeu Fabra Barcelona (UPF), National Technical University of Athens Athens (NTUA), Helmholtz Zentrum für Umweltforschung = Helmholtz Centre for Environmental Research (UFZ), Environmental Institute Kos, Uppsala University, Leiden Academic Center for Drug Research, United States Environmental Protection Agency Cincinnati, Universität Wien = University of Vienna, National Institute of Biology Ljubljana (NIB), This work received funding from the European Union’s Horizon 2020 research infrastrcuture programme via the OpenRiskNet project under grant agreement No. 731075.This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 681002 (EU-ToxRisk).This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 814572.SN acknowledges BMBF funding under grant number 031L0107.This work was supported by OBERON (https://oberon-4eu.comTest), a project funded by the European Union's Horizon 2020 research and innovation program under the grant agreement No. 825712.This work was supported by the European Union,'s Horizon 2020 research and innovation program HBM4EU, grant agreement No. 733032 (https://www.hbm4eu.euTest).Supported by the European Union’s Horizon 2020 programme under the Marie Skłodowska-Curie grant agreement No. 859891.Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article, and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer/World Health Organization.This work was supported by the European Union,'s Horizon 2020 research and innovation program HARMLESS, grant agreement No. 953183.This work was supported by the European Union,'s Horizon 2020 research and innovation program Gov4Nano, grant agreement No. 814401.This work was supported by the Swedish Fund for Research Without Animal Experiments under grant number N2020-0005.This work was supported by the European Union,'s Horizon 2020 research and innovation program NTS-EXPOSURE, Grant agreement ID: 896141.This work was supported by the European Union,'s LIFE program LIFE-APEX, Grant agreement ID: LIFE17 ENV/SK/000355.This study was funded by the German Environment Agency within the PHION project (grant number 3718 674150).The Data Readiness Group is supported, in this ELIXIR Community, by the H2020 Precision Toxicology project (H2020-EU 965406).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome ISA-InterMine project (208381/A/17/Z).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome FAIRsharing project (212930/Z/18/Z).This work received funding from the European Union’s Horizon 2020 research and innovation programme RiskGONE Project under grant agreement No. 814425.NR's research is funded by a Miguel Servet contract (CO19/00060) from Instituto de Salud Carlos III, cofinanced by the European Union.UM (Uni. of Tartu) is grateful for support to Ministry of Education and Research, Republic of Estonia through Estonian Research Council (grant number IUT34-14) and to European Union European Regional Development Fund through Foundation Archimedes (grant number TK143, Centre of Excellence in Molecular Cell Engineering).Development and Implementation of a Sustainable Modelling Platform for NanoInformatics.Linking LRI Ambit chemoinformatic system with the IUCLID substance database to support read-across of substance endpoint data and category formation.This work was supported by the French Ministry of Research and National Research Agency as part of the French MetaboHUB, the national metabolomics and fluxomics infrastructure (Grant ANR-INBS-0010).This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement GOLIATH No. 825489., ANR-11-INBS-0010,METABOHUB,Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation(2011), European Project: 681002,H2020,H2020-PHC-2015-single-stage_RTD,EU-ToxRisk(2016), European Project: 825712,H2020-EU.3.1.1. - Understanding health, wellbeing and disease,H2020-SC1-2018-Single-Stage-RTD,OBERON(2019), European Project: 733032,H2020,HBM4EU(2017), European Project: 814425,H2020,RiskGONE(2019), European Project: 825489,H2020,GOLIATH(2019)

المصدر: ISSN: 2046-1402 ; F1000Research ; https://pasteur.hal.science/pasteur-03680151Test ; F1000Research, 2021, 10, pp.1129. ⟨10.12688/f1000research.74502.1⟩.

مصطلحات موضوعية: Toxicology, ELIXIR, interoperability, FAIR, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], [SDV.TOX]Life Sciences [q-bio]/Toxicology

العلاقة: info:eu-repo/grantAgreement//681002/EU/An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century/EU-ToxRisk; info:eu-repo/grantAgreement//825712/EU/An integrative strategy of testing systems for identification of EDs related to metabolic disorders/OBERON; info:eu-repo/grantAgreement//733032/EU/European Human Biomonitoring Initiative/HBM4EU; info:eu-repo/grantAgreement//814425/EU/Risk Governance of Nanotechnology/RiskGONE; info:eu-repo/grantAgreement//825489/EU/Beating Goliath: Generation Of NoveL, Integrated and Internationally Harmonised Approaches for Testing Metabolism Disrupting Compounds/GOLIATH; pasteur-03680151; https://pasteur.hal.science/pasteur-03680151Test; https://pasteur.hal.science/pasteur-03680151/documentTest; https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

الإتاحة: https://doi.org/10.12688/f1000research.74502.1Test
https://pasteur.hal.science/pasteur-03680151Test
https://pasteur.hal.science/pasteur-03680151/documentTest
https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

المؤلفون: Martens, Marvin, Stierum, Rob, Schymanski, Emma, Evelo, Chris, Aalizadeh, Reza, Aladjov, Hristo, Arturi, Kasia, Audouze, Karine, Babica, Pavel, Berka, Karel, Bessems, Jos, Blaha, Ludek, Bolton, Evan, Cases, Montserrat, Damalas, Dimitrios, Dave, Kirtan, Dilger, Marco, Exner, Thomas, Geerke, Daan, Grafström, Roland, Gray, Alasdair, Hancock, John, Hollert, Henner, Jeliazkova, Nina, Jennen, Danyel, Jourdan, Fabien, Kahlem, Pascal, Klanova, Jana, Kleinjans, Jos, Kondic, Todor, Kone, Boï, Lynch, Iseult, Maran, Uko, Martinez Cuesta, Sergio, Ménager, Hervé, Neumann, Steffen, Nymark, Penny, Oberacher, Herbert, Ramirez, Noelia, Remy, Sylvie, Rocca-Serra, Philippe, Salek, Reza, Sallach, Brett, Sansone, Susanna-Assunta, Sanz, Ferran, Sarimveis, Haralambos, Sarntivijai, Sirarat, Schulze, Tobias, Slobodnik, Jaroslav, Spjuth, Ola, Tedds, Jonathan, Thomaidis, Nikolaos, Weber, Ralf, van Westen, Gerard, Wheelock, Craig, Williams, Antony, Witters, Hilda, Zdrazil, Barbara, Županič, Anže, Willighagen, Egon

المساهمون: Department of Bioinformatics, Maastricht University Medical Center (BiGCaT), The Netherlands Organisation for Applied Scientific Research (TNO), Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg Luxembourg, Maastricht Centre for Systems Biology, Maastricht University Medical Center (MaCSBio), National and Kapodistrian University of Athens (NKUA), Bulgarian Academy of Sciences (BAS), Swiss Federal Institute of Aquatic Science & Technology (EAWA), Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire (T3S - UMR_S 1124), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Research Centre for Toxic Compounds in the Environment Brno (RECETOX / MUNI), Faculty of Science Brno (SCI / MUNI), Masaryk University Brno (MUNI)-Masaryk University Brno (MUNI), Palacky University Olomouc, Flemish Institute for Technological Research (VITO), National Center for Biotechnology Information (NCBI), National Institutes of Health Bethesda, MD, USA (NIH), Chemotargets SL, GSFC University, Forschungs- und Beratungsinstitut Gefahrstoffe GmbH (FoBiG), Seven Past Nine, Vrije Universiteit Amsterdam Amsterdam (VU), Karolinska Institutet Stockholm, Misvik Biology, Heriot-Watt University Edinburgh (HWU), ELIXIR Hub Cambridge, Goethe University Frankfurt, Ideaconsult, Maastricht University Maastricht, ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), MetaboHUB-MetaToul, MetaboHUB-Génopole Toulouse Midi-Pyrénées Auzeville (GENOTOUL), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Faculté de Médecine, de pharmacie et d’Odonto-Stomatologie Bamako, Mali (FMPOS), Université de Bamako, University of Birmingham Birmingham, University of Tartu, AstraZeneca Cambridge, UK, Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Institut Français de Bioinformatique (IFB-CORE), Institut National de Recherche en Informatique et en Automatique (Inria)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Leibniz Institute of Plant Biochemistry (IPB), Innsbruck Medical University = Medizinische Universität Innsbruck (IMU), Universitat Rovira i Virgili, University of Oxford, Centre International de Recherche contre le Cancer - International Agency for Research on Cancer (CIRC - IARC), Organisation Mondiale de la Santé / World Health Organization Office Genève, Suisse (OMS / WHO), University of York York, UK, Universitat Pompeu Fabra Barcelona (UPF), National Technical University of Athens Athens (NTUA), Helmholtz Zentrum für Umweltforschung = Helmholtz Centre for Environmental Research (UFZ), Environmental Institute Kos, Uppsala University, Leiden Academic Center for Drug Research, United States Environmental Protection Agency Cincinnati, Universität Wien = University of Vienna, National Institute of Biology Ljubljana (NIB), This work received funding from the European Union’s Horizon 2020 research infrastrcuture programme via the OpenRiskNet project under grant agreement No. 731075.This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 681002 (EU-ToxRisk).This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 814572.SN acknowledges BMBF funding under grant number 031L0107.This work was supported by OBERON (https://oberon-4eu.comTest), a project funded by the European Union's Horizon 2020 research and innovation program under the grant agreement No. 825712.This work was supported by the European Union,'s Horizon 2020 research and innovation program HBM4EU, grant agreement No. 733032 (https://www.hbm4eu.euTest).Supported by the European Union’s Horizon 2020 programme under the Marie Skłodowska-Curie grant agreement No. 859891.Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article, and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer/World Health Organization.This work was supported by the European Union,'s Horizon 2020 research and innovation program HARMLESS, grant agreement No. 953183.This work was supported by the European Union,'s Horizon 2020 research and innovation program Gov4Nano, grant agreement No. 814401.This work was supported by the Swedish Fund for Research Without Animal Experiments under grant number N2020-0005.This work was supported by the European Union,'s Horizon 2020 research and innovation program NTS-EXPOSURE, Grant agreement ID: 896141.This work was supported by the European Union,'s LIFE program LIFE-APEX, Grant agreement ID: LIFE17 ENV/SK/000355.This study was funded by the German Environment Agency within the PHION project (grant number 3718 674150).The Data Readiness Group is supported, in this ELIXIR Community, by the H2020 Precision Toxicology project (H2020-EU 965406).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome ISA-InterMine project (208381/A/17/Z).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome FAIRsharing project (212930/Z/18/Z).This work received funding from the European Union’s Horizon 2020 research and innovation programme RiskGONE Project under grant agreement No. 814425.NR's research is funded by a Miguel Servet contract (CO19/00060) from Instituto de Salud Carlos III, cofinanced by the European Union.UM (Uni. of Tartu) is grateful for support to Ministry of Education and Research, Republic of Estonia through Estonian Research Council (grant number IUT34-14) and to European Union European Regional Development Fund through Foundation Archimedes (grant number TK143, Centre of Excellence in Molecular Cell Engineering).Development and Implementation of a Sustainable Modelling Platform for NanoInformatics.Linking LRI Ambit chemoinformatic system with the IUCLID substance database to support read-across of substance endpoint data and category formation.This work was supported by the French Ministry of Research and National Research Agency as part of the French MetaboHUB, the national metabolomics and fluxomics infrastructure (Grant ANR-INBS-0010).This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement GOLIATH No. 825489., ANR-11-INBS-0010,METABOHUB,Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation(2011), European Project: 681002,H2020,H2020-PHC-2015-single-stage_RTD,EU-ToxRisk(2016), European Project: 825712,H2020-EU.3.1.1. - Understanding health, wellbeing and disease,H2020-SC1-2018-Single-Stage-RTD,OBERON(2019), European Project: 733032,H2020,HBM4EU(2017), European Project: 814425,H2020,RiskGONE(2019), European Project: 825489,H2020,GOLIATH(2019)

المصدر: ISSN: 2046-1402 ; F1000Research ; https://pasteur.hal.science/pasteur-03680151Test ; F1000Research, 2021, 10, pp.1129. ⟨10.12688/f1000research.74502.1⟩.

مصطلحات موضوعية: Toxicology, ELIXIR, interoperability, FAIR, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], [SDV.TOX]Life Sciences [q-bio]/Toxicology

العلاقة: info:eu-repo/grantAgreement//681002/EU/An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century/EU-ToxRisk; info:eu-repo/grantAgreement//825712/EU/An integrative strategy of testing systems for identification of EDs related to metabolic disorders/OBERON; info:eu-repo/grantAgreement//733032/EU/European Human Biomonitoring Initiative/HBM4EU; info:eu-repo/grantAgreement//814425/EU/Risk Governance of Nanotechnology/RiskGONE; info:eu-repo/grantAgreement//825489/EU/Beating Goliath: Generation Of NoveL, Integrated and Internationally Harmonised Approaches for Testing Metabolism Disrupting Compounds/GOLIATH; pasteur-03680151; https://pasteur.hal.science/pasteur-03680151Test; https://pasteur.hal.science/pasteur-03680151/documentTest; https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

الإتاحة: https://doi.org/10.12688/f1000research.74502.1Test
https://pasteur.hal.science/pasteur-03680151Test
https://pasteur.hal.science/pasteur-03680151/documentTest
https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

المؤلفون: Martens, Marvin, Stierum, Rob, Schymanski, Emma, Evelo, Chris, Aalizadeh, Reza, Aladjov, Hristo, Arturi, Kasia, Audouze, Karine, Babica, Pavel, Berka, Karel, Bessems, Jos, Blaha, Ludek, Bolton, Evan, Cases, Montserrat, Damalas, Dimitrios, Dave, Kirtan, Dilger, Marco, Exner, Thomas, Geerke, Daan, Grafström, Roland, Gray, Alasdair, Hancock, John, Hollert, Henner, Jeliazkova, Nina, Jennen, Danyel, Jourdan, Fabien, Kahlem, Pascal, Klanova, Jana, Kleinjans, Jos, Kondic, Todor, Kone, Boï, Lynch, Iseult, Maran, Uko, Martinez Cuesta, Sergio, Ménager, Hervé, Neumann, Steffen, Nymark, Penny, Oberacher, Herbert, Ramirez, Noelia, Remy, Sylvie, Rocca-Serra, Philippe, Salek, Reza, Sallach, Brett, Sansone, Susanna-Assunta, Sanz, Ferran, Sarimveis, Haralambos, Sarntivijai, Sirarat, Schulze, Tobias, Slobodnik, Jaroslav, Spjuth, Ola, Tedds, Jonathan, Thomaidis, Nikolaos, Weber, Ralf, van Westen, Gerard, Wheelock, Craig, Williams, Antony, Witters, Hilda, Zdrazil, Barbara, Županič, Anže, Willighagen, Egon

المساهمون: Department of Bioinformatics, Maastricht University Medical Center (BiGCaT), The Netherlands Organisation for Applied Scientific Research (TNO), Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg Luxembourg, Maastricht Centre for Systems Biology, Maastricht University Medical Center (MaCSBio), National and Kapodistrian University of Athens (NKUA), Bulgarian Academy of Sciences (BAS), Swiss Federal Institute of Aquatic Science & Technology (EAWA), Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire (T3S - UMR_S 1124), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Research Centre for Toxic Compounds in the Environment Brno (RECETOX / MUNI), Faculty of Science Brno (SCI / MUNI), Masaryk University Brno (MUNI)-Masaryk University Brno (MUNI), Palacky University Olomouc, Flemish Institute for Technological Research (VITO), National Center for Biotechnology Information (NCBI), National Institutes of Health Bethesda, MD, USA (NIH), Chemotargets SL, GSFC University, Forschungs- und Beratungsinstitut Gefahrstoffe GmbH (FoBiG), Seven Past Nine, Vrije Universiteit Amsterdam Amsterdam (VU), Karolinska Institutet Stockholm, Misvik Biology, Heriot-Watt University Edinburgh (HWU), ELIXIR Hub Cambridge, Goethe University Frankfurt, Ideaconsult, Maastricht University Maastricht, ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), MetaboHUB-MetaToul, MetaboHUB-Génopole Toulouse Midi-Pyrénées Auzeville (GENOTOUL), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Faculté de Médecine, de pharmacie et d’Odonto-Stomatologie Bamako, Mali (FMPOS), Université de Bamako, University of Birmingham Birmingham, University of Tartu, AstraZeneca Cambridge, UK, Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Institut Français de Bioinformatique (IFB-CORE), Institut National de Recherche en Informatique et en Automatique (Inria)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Leibniz Institute of Plant Biochemistry (IPB), Innsbruck Medical University = Medizinische Universität Innsbruck (IMU), Universitat Rovira i Virgili, University of Oxford, Centre International de Recherche contre le Cancer - International Agency for Research on Cancer (CIRC - IARC), Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), University of York York, UK, Universitat Pompeu Fabra Barcelona (UPF), National Technical University of Athens Athens (NTUA), Helmholtz Zentrum für Umweltforschung = Helmholtz Centre for Environmental Research (UFZ), Environmental Institute Kos, Uppsala University, Leiden Academic Center for Drug Research, United States Environmental Protection Agency Cincinnati, University of Vienna Vienna, National Institute of Biology Ljubljana (NIB), This work received funding from the European Union’s Horizon 2020 research infrastrcuture programme via the OpenRiskNet project under grant agreement No. 731075.This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 681002 (EU-ToxRisk).This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 814572.SN acknowledges BMBF funding under grant number 031L0107.This work was supported by OBERON (https://oberon-4eu.comTest), a project funded by the European Union's Horizon 2020 research and innovation program under the grant agreement No. 825712.This work was supported by the European Union,'s Horizon 2020 research and innovation program HBM4EU, grant agreement No. 733032 (https://www.hbm4eu.euTest).Supported by the European Union’s Horizon 2020 programme under the Marie Skłodowska-Curie grant agreement No. 859891.Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article, and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer/World Health Organization.This work was supported by the European Union,'s Horizon 2020 research and innovation program HARMLESS, grant agreement No. 953183.This work was supported by the European Union,'s Horizon 2020 research and innovation program Gov4Nano, grant agreement No. 814401.This work was supported by the Swedish Fund for Research Without Animal Experiments under grant number N2020-0005.This work was supported by the European Union,'s Horizon 2020 research and innovation program NTS-EXPOSURE, Grant agreement ID: 896141.This work was supported by the European Union,'s LIFE program LIFE-APEX, Grant agreement ID: LIFE17 ENV/SK/000355.This study was funded by the German Environment Agency within the PHION project (grant number 3718 674150).The Data Readiness Group is supported, in this ELIXIR Community, by the H2020 Precision Toxicology project (H2020-EU 965406).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome ISA-InterMine project (208381/A/17/Z).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome FAIRsharing project (212930/Z/18/Z).This work received funding from the European Union’s Horizon 2020 research and innovation programme RiskGONE Project under grant agreement No. 814425.NR's research is funded by a Miguel Servet contract (CO19/00060) from Instituto de Salud Carlos III, cofinanced by the European Union.UM (Uni. of Tartu) is grateful for support to Ministry of Education and Research, Republic of Estonia through Estonian Research Council (grant number IUT34-14) and to European Union European Regional Development Fund through Foundation Archimedes (grant number TK143, Centre of Excellence in Molecular Cell Engineering).Development and Implementation of a Sustainable Modelling Platform for NanoInformatics.Linking LRI Ambit chemoinformatic system with the IUCLID substance database to support read-across of substance endpoint data and category formation.This work was supported by the French Ministry of Research and National Research Agency as part of the French MetaboHUB, the national metabolomics and fluxomics infrastructure (Grant ANR-INBS-0010).This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement GOLIATH No. 825489., ANR-11-INBS-0010,METABOHUB,Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation(2011), European Project: 681002,H2020,H2020-PHC-2015-single-stage_RTD,EU-ToxRisk(2016), European Project: 825712,H2020-EU.3.1.1. - Understanding health, wellbeing and disease,H2020-SC1-2018-Single-Stage-RTD,OBERON(2019), European Project: 733032,H2020,HBM4EU(2017), European Project: 814425,H2020,RiskGONE(2019), European Project: 825489,H2020,GOLIATH(2019)

المصدر: ISSN: 2046-1402 ; F1000Research ; https://pasteur.hal.science/pasteur-03680151Test ; F1000Research, 2021, 10, pp.1129. ⟨10.12688/f1000research.74502.1⟩.

مصطلحات موضوعية: Toxicology, ELIXIR, interoperability, FAIR, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], [SDV.TOX]Life Sciences [q-bio]/Toxicology

العلاقة: info:eu-repo/grantAgreement//681002/EU/An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century/EU-ToxRisk; info:eu-repo/grantAgreement//825712/EU/An integrative strategy of testing systems for identification of EDs related to metabolic disorders/OBERON; info:eu-repo/grantAgreement//733032/EU/European Human Biomonitoring Initiative/HBM4EU; info:eu-repo/grantAgreement//814425/EU/Risk Governance of Nanotechnology/RiskGONE; info:eu-repo/grantAgreement//825489/EU/Beating Goliath: Generation Of NoveL, Integrated and Internationally Harmonised Approaches for Testing Metabolism Disrupting Compounds/GOLIATH; pasteur-03680151; https://pasteur.hal.science/pasteur-03680151Test; https://pasteur.hal.science/pasteur-03680151/documentTest; https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

الإتاحة: https://doi.org/10.12688/f1000research.74502.1Test
https://pasteur.hal.science/pasteur-03680151Test
https://pasteur.hal.science/pasteur-03680151/documentTest
https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

المؤلفون: Martens, Marvin, Stierum, Rob, Schymanski, Emma, Evelo, Chris, Aalizadeh, Reza, Aladjov, Hristo, Arturi, Kasia, Audouze, Karine, Babica, Pavel, Berka, Karel, Bessems, Jos, Blaha, Ludek, Bolton, Evan, Cases, Montserrat, Damalas, Dimitrios, Dave, Kirtan, Dilger, Marco, Exner, Thomas, Geerke, Daan, Grafström, Roland, Gray, Alasdair, Hancock, John, Hollert, Henner, Jeliazkova, Nina, Jennen, Danyel, Jourdan, Fabien, Kahlem, Pascal, Klanova, Jana, Kleinjans, Jos, Kondic, Todor, Kone, Boï, Lynch, Iseult, Maran, Uko, Martinez Cuesta, Sergio, Ménager, Hervé, Neumann, Steffen, Nymark, Penny, Oberacher, Herbert, Ramirez, Noelia, Remy, Sylvie, Rocca-Serra, Philippe, Salek, Reza, Sallach, Brett, Sansone, Susanna-Assunta, Sanz, Ferran, Sarimveis, Haralambos, Sarntivijai, Sirarat, Schulze, Tobias, Slobodnik, Jaroslav, Spjuth, Ola, Tedds, Jonathan, Thomaidis, Nikolaos, Weber, Ralf, van Westen, Gerard, Wheelock, Craig, Williams, Antony, Witters, Hilda, Zdrazil, Barbara, Županič, Anže, Willighagen, Egon

المساهمون: Department of Bioinformatics, Maastricht University Medical Center (BiGCaT), The Netherlands Organisation for Applied Scientific Research (TNO), Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg Luxembourg, Maastricht Centre for Systems Biology, Maastricht University Medical Center (MaCSBio), National and Kapodistrian University of Athens (NKUA), Bulgarian Academy of Sciences (BAS), Swiss Federal Institute of Aquatic Science & Technology (EAWA), Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire (T3S - UMR_S 1124), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Research Centre for Toxic Compounds in the Environment Brno (RECETOX / MUNI), Faculty of Science Brno (SCI / MUNI), Masaryk University Brno (MUNI)-Masaryk University Brno (MUNI), Palacky University Olomouc, Flemish Institute for Technological Research (VITO), National Center for Biotechnology Information (NCBI), National Institutes of Health Bethesda, MD, USA (NIH), Chemotargets SL, GSFC University, Forschungs- und Beratungsinstitut Gefahrstoffe GmbH (FoBiG), Seven Past Nine, Vrije Universiteit Amsterdam Amsterdam (VU), Karolinska Institutet Stockholm, Misvik Biology, Heriot-Watt University Edinburgh (HWU), ELIXIR Hub Cambridge, Goethe University Frankfurt, Ideaconsult, Maastricht University Maastricht, ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), MetaboHUB-MetaToul, MetaboHUB-Génopole Toulouse Midi-Pyrénées Auzeville (GENOTOUL), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Faculté de Médecine, de pharmacie et d’Odonto-Stomatologie Bamako, Mali (FMPOS), Université de Bamako, University of Birmingham Birmingham, University of Tartu, AstraZeneca Cambridge, UK, Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Institut Français de Bioinformatique (IFB-CORE), Institut National de Recherche en Informatique et en Automatique (Inria)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Leibniz Institute of Plant Biochemistry (IPB), Innsbruck Medical University = Medizinische Universität Innsbruck (IMU), Universitat Rovira i Virgili, University of Oxford, Centre International de Recherche contre le Cancer - International Agency for Research on Cancer (CIRC - IARC), Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), University of York York, UK, Universitat Pompeu Fabra Barcelona (UPF), National Technical University of Athens Athens (NTUA), Helmholtz Zentrum für Umweltforschung = Helmholtz Centre for Environmental Research (UFZ), Environmental Institute Kos, Uppsala University, Leiden Academic Center for Drug Research, United States Environmental Protection Agency Cincinnati, University of Vienna Vienna, National Institute of Biology Ljubljana (NIB), This work received funding from the European Union’s Horizon 2020 research infrastrcuture programme via the OpenRiskNet project under grant agreement No. 731075.This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 681002 (EU-ToxRisk).This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 814572.SN acknowledges BMBF funding under grant number 031L0107.This work was supported by OBERON (https://oberon-4eu.comTest), a project funded by the European Union's Horizon 2020 research and innovation program under the grant agreement No. 825712.This work was supported by the European Union,'s Horizon 2020 research and innovation program HBM4EU, grant agreement No. 733032 (https://www.hbm4eu.euTest).Supported by the European Union’s Horizon 2020 programme under the Marie Skłodowska-Curie grant agreement No. 859891.Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article, and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer/World Health Organization.This work was supported by the European Union,'s Horizon 2020 research and innovation program HARMLESS, grant agreement No. 953183.This work was supported by the European Union,'s Horizon 2020 research and innovation program Gov4Nano, grant agreement No. 814401.This work was supported by the Swedish Fund for Research Without Animal Experiments under grant number N2020-0005.This work was supported by the European Union,'s Horizon 2020 research and innovation program NTS-EXPOSURE, Grant agreement ID: 896141.This work was supported by the European Union,'s LIFE program LIFE-APEX, Grant agreement ID: LIFE17 ENV/SK/000355.This study was funded by the German Environment Agency within the PHION project (grant number 3718 674150).The Data Readiness Group is supported, in this ELIXIR Community, by the H2020 Precision Toxicology project (H2020-EU 965406).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome ISA-InterMine project (208381/A/17/Z).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome FAIRsharing project (212930/Z/18/Z).This work received funding from the European Union’s Horizon 2020 research and innovation programme RiskGONE Project under grant agreement No. 814425.NR's research is funded by a Miguel Servet contract (CO19/00060) from Instituto de Salud Carlos III, cofinanced by the European Union.UM (Uni. of Tartu) is grateful for support to Ministry of Education and Research, Republic of Estonia through Estonian Research Council (grant number IUT34-14) and to European Union European Regional Development Fund through Foundation Archimedes (grant number TK143, Centre of Excellence in Molecular Cell Engineering).Development and Implementation of a Sustainable Modelling Platform for NanoInformatics.Linking LRI Ambit chemoinformatic system with the IUCLID substance database to support read-across of substance endpoint data and category formation.This work was supported by the French Ministry of Research and National Research Agency as part of the French MetaboHUB, the national metabolomics and fluxomics infrastructure (Grant ANR-INBS-0010).This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement GOLIATH No. 825489., ANR-11-INBS-0010,METABOHUB,Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation(2011), European Project: 681002,H2020,H2020-PHC-2015-single-stage_RTD,EU-ToxRisk(2016), European Project: 825712,H2020-EU.3.1.1. - Understanding health, wellbeing and disease,H2020-SC1-2018-Single-Stage-RTD,OBERON(2019), European Project: 733032,H2020,HBM4EU(2017), European Project: 814425,H2020,RiskGONE(2019), European Project: 825489,H2020,GOLIATH(2019)

المصدر: ISSN: 2046-1402 ; F1000Research ; https://pasteur.hal.science/pasteur-03680151Test ; F1000Research, 2021, 10, pp.1129. ⟨10.12688/f1000research.74502.1⟩.

مصطلحات موضوعية: Toxicology, ELIXIR, interoperability, FAIR, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], [SDV.TOX]Life Sciences [q-bio]/Toxicology

العلاقة: info:eu-repo/grantAgreement//681002/EU/An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century/EU-ToxRisk; info:eu-repo/grantAgreement//825712/EU/An integrative strategy of testing systems for identification of EDs related to metabolic disorders/OBERON; info:eu-repo/grantAgreement//733032/EU/European Human Biomonitoring Initiative/HBM4EU; info:eu-repo/grantAgreement//814425/EU/Risk Governance of Nanotechnology/RiskGONE; info:eu-repo/grantAgreement//825489/EU/Beating Goliath: Generation Of NoveL, Integrated and Internationally Harmonised Approaches for Testing Metabolism Disrupting Compounds/GOLIATH; pasteur-03680151; https://pasteur.hal.science/pasteur-03680151Test; https://pasteur.hal.science/pasteur-03680151/documentTest; https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

الإتاحة: https://doi.org/10.12688/f1000research.74502.1Test
https://pasteur.hal.science/pasteur-03680151Test
https://pasteur.hal.science/pasteur-03680151/documentTest
https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

المؤلفون: Martens, Marvin, Stierum, Rob, Schymanski, Emma, Evelo, Chris, Aalizadeh, Reza, Aladjov, Hristo, Arturi, Kasia, Audouze, Karine, Babica, Pavel, Berka, Karel, Bessems, Jos, Blaha, Ludek, Bolton, Evan, Cases, Montserrat, Damalas, Dimitrios, Dave, Kirtan, Dilger, Marco, Exner, Thomas, Geerke, Daan, Grafström, Roland, Gray, Alasdair, Hancock, John, Hollert, Henner, Jeliazkova, Nina, Jennen, Danyel, Jourdan, Fabien, Kahlem, Pascal, Klanova, Jana, Kleinjans, Jos, Kondic, Todor, Kone, Boï, Lynch, Iseult, Maran, Uko, Martinez Cuesta, Sergio, Ménager, Hervé, Neumann, Steffen, Nymark, Penny, Oberacher, Herbert, Ramirez, Noelia, Remy, Sylvie, Rocca-Serra, Philippe, Salek, Reza, Sallach, Brett, Sansone, Susanna-Assunta, Sanz, Ferran, Sarimveis, Haralambos, Sarntivijai, Sirarat, Schulze, Tobias, Slobodnik, Jaroslav, Spjuth, Ola, Tedds, Jonathan, Thomaidis, Nikolaos, Weber, Ralf, van Westen, Gerard, Wheelock, Craig, Williams, Antony, Witters, Hilda, Zdrazil, Barbara, Županič, Anže, Willighagen, Egon

المساهمون: Department of Bioinformatics, Maastricht University Medical Center (BiGCaT), The Netherlands Organisation for Applied Scientific Research (TNO), Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg Luxembourg, Maastricht Centre for Systems Biology, Maastricht University Medical Center (MaCSBio), National and Kapodistrian University of Athens (NKUA), Bulgarian Academy of Sciences (BAS), Swiss Federal Institute of Aquatic Science & Technology (EAWA), Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire (T3S - UMR_S 1124), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Research Centre for Toxic Compounds in the Environment Brno (RECETOX / MUNI), Faculty of Science Brno (SCI / MUNI), Masaryk University Brno (MUNI)-Masaryk University Brno (MUNI), Palacky University Olomouc, Flemish Institute for Technological Research (VITO), National Center for Biotechnology Information (NCBI), National Institutes of Health Bethesda, MD, USA (NIH), Chemotargets SL, GSFC University, Forschungs- und Beratungsinstitut Gefahrstoffe GmbH (FoBiG), Seven Past Nine, Vrije Universiteit Amsterdam Amsterdam (VU), Karolinska Institutet Stockholm, Misvik Biology, Heriot-Watt University Edinburgh (HWU), ELIXIR Hub Cambridge, Goethe University Frankfurt, Ideaconsult, Maastricht University Maastricht, ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), MetaboHUB-MetaToul, MetaboHUB-Génopole Toulouse Midi-Pyrénées Auzeville (GENOTOUL), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Faculté de Médecine, de pharmacie et d’Odonto-Stomatologie Bamako, Mali (FMPOS), Université de Bamako, University of Birmingham Birmingham, University of Tartu, AstraZeneca Cambridge, UK, Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Institut Français de Bioinformatique (IFB-CORE), Institut National de Recherche en Informatique et en Automatique (Inria)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Leibniz Institute of Plant Biochemistry (IPB), Innsbruck Medical University = Medizinische Universität Innsbruck (IMU), Universitat Rovira i Virgili, University of Oxford, Centre International de Recherche contre le Cancer - International Agency for Research on Cancer (CIRC - IARC), Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), University of York York, UK, Universitat Pompeu Fabra Barcelona (UPF), National Technical University of Athens Athens (NTUA), Helmholtz Zentrum für Umweltforschung = Helmholtz Centre for Environmental Research (UFZ), Environmental Institute Kos, Uppsala University, Leiden Academic Center for Drug Research, United States Environmental Protection Agency Cincinnati, University of Vienna Vienna, National Institute of Biology Ljubljana (NIB), This work received funding from the European Union’s Horizon 2020 research infrastrcuture programme via the OpenRiskNet project under grant agreement No. 731075.This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 681002 (EU-ToxRisk).This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 814572.SN acknowledges BMBF funding under grant number 031L0107.This work was supported by OBERON (https://oberon-4eu.comTest), a project funded by the European Union's Horizon 2020 research and innovation program under the grant agreement No. 825712.This work was supported by the European Union,'s Horizon 2020 research and innovation program HBM4EU, grant agreement No. 733032 (https://www.hbm4eu.euTest).Supported by the European Union’s Horizon 2020 programme under the Marie Skłodowska-Curie grant agreement No. 859891.Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article, and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer/World Health Organization.This work was supported by the European Union,'s Horizon 2020 research and innovation program HARMLESS, grant agreement No. 953183.This work was supported by the European Union,'s Horizon 2020 research and innovation program Gov4Nano, grant agreement No. 814401.This work was supported by the Swedish Fund for Research Without Animal Experiments under grant number N2020-0005.This work was supported by the European Union,'s Horizon 2020 research and innovation program NTS-EXPOSURE, Grant agreement ID: 896141.This work was supported by the European Union,'s LIFE program LIFE-APEX, Grant agreement ID: LIFE17 ENV/SK/000355.This study was funded by the German Environment Agency within the PHION project (grant number 3718 674150).The Data Readiness Group is supported, in this ELIXIR Community, by the H2020 Precision Toxicology project (H2020-EU 965406).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome ISA-InterMine project (208381/A/17/Z).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome FAIRsharing project (212930/Z/18/Z).This work received funding from the European Union’s Horizon 2020 research and innovation programme RiskGONE Project under grant agreement No. 814425.NR's research is funded by a Miguel Servet contract (CO19/00060) from Instituto de Salud Carlos III, cofinanced by the European Union.UM (Uni. of Tartu) is grateful for support to Ministry of Education and Research, Republic of Estonia through Estonian Research Council (grant number IUT34-14) and to European Union European Regional Development Fund through Foundation Archimedes (grant number TK143, Centre of Excellence in Molecular Cell Engineering).Development and Implementation of a Sustainable Modelling Platform for NanoInformatics.Linking LRI Ambit chemoinformatic system with the IUCLID substance database to support read-across of substance endpoint data and category formation.This work was supported by the French Ministry of Research and National Research Agency as part of the French MetaboHUB, the national metabolomics and fluxomics infrastructure (Grant ANR-INBS-0010).This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement GOLIATH No. 825489., ANR-11-INBS-0010,METABOHUB,Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation(2011), European Project: 681002,H2020,H2020-PHC-2015-single-stage_RTD,EU-ToxRisk(2016), European Project: 825712,H2020-EU.3.1.1. - Understanding health, wellbeing and disease,H2020-SC1-2018-Single-Stage-RTD,OBERON(2019), European Project: 733032,H2020,HBM4EU(2017), European Project: 814425,H2020,RiskGONE(2019), European Project: 825489,H2020,GOLIATH(2019)

المصدر: ISSN: 2046-1402 ; F1000Research ; https://pasteur.hal.science/pasteur-03680151Test ; F1000Research, 2021, 10, pp.1129. ⟨10.12688/f1000research.74502.1⟩.

مصطلحات موضوعية: Toxicology, ELIXIR, interoperability, FAIR, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], [SDV.TOX]Life Sciences [q-bio]/Toxicology

العلاقة: info:eu-repo/grantAgreement//681002/EU/An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century/EU-ToxRisk; info:eu-repo/grantAgreement//825712/EU/An integrative strategy of testing systems for identification of EDs related to metabolic disorders/OBERON; info:eu-repo/grantAgreement//733032/EU/European Human Biomonitoring Initiative/HBM4EU; info:eu-repo/grantAgreement//814425/EU/Risk Governance of Nanotechnology/RiskGONE; info:eu-repo/grantAgreement//825489/EU/Beating Goliath: Generation Of NoveL, Integrated and Internationally Harmonised Approaches for Testing Metabolism Disrupting Compounds/GOLIATH; pasteur-03680151; https://pasteur.hal.science/pasteur-03680151Test; https://pasteur.hal.science/pasteur-03680151/documentTest; https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

الإتاحة: https://doi.org/10.12688/f1000research.74502.1Test
https://pasteur.hal.science/pasteur-03680151Test
https://pasteur.hal.science/pasteur-03680151/documentTest
https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

المؤلفون: Martens, Marvin, Stierum, Rob, Schymanski, Emma, Evelo, Chris, Aalizadeh, Reza, Aladjov, Hristo, Arturi, Kasia, Audouze, Karine, Babica, Pavel, Berka, Karel, Bessems, Jos, Blaha, Ludek, Bolton, Evan, Cases, Montserrat, Damalas, Dimitrios, Dave, Kirtan, Dilger, Marco, Exner, Thomas, Geerke, Daan, Grafström, Roland, Gray, Alasdair, Hancock, John, Hollert, Henner, Jeliazkova, Nina, Jennen, Danyel, Jourdan, Fabien, Kahlem, Pascal, Klanova, Jana, Kleinjans, Jos, Kondic, Todor, Kone, Boï, Lynch, Iseult, Maran, Uko, Martinez Cuesta, Sergio, Ménager, Hervé, Neumann, Steffen, Nymark, Penny, Oberacher, Herbert, Ramirez, Noelia, Remy, Sylvie, Rocca-Serra, Philippe, Salek, Reza, Sallach, Brett, Sansone, Susanna-Assunta, Sanz, Ferran, Sarimveis, Haralambos, Sarntivijai, Sirarat, Schulze, Tobias, Slobodnik, Jaroslav, Spjuth, Ola, Tedds, Jonathan, Thomaidis, Nikolaos, Weber, Ralf, van Westen, Gerard, Wheelock, Craig, Williams, Antony, Witters, Hilda, Zdrazil, Barbara, Županič, Anže, Willighagen, Egon

المساهمون: Department of Bioinformatics, Maastricht University Medical Center (BiGCaT), The Netherlands Organisation for Applied Scientific Research (TNO), Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg Luxembourg, Maastricht Centre for Systems Biology, Maastricht University Medical Center (MaCSBio), National and Kapodistrian University of Athens (NKUA), Bulgarian Academy of Sciences (BAS), Swiss Federal Institute of Aquatic Science & Technology (EAWA), Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire (T3S - UMR_S 1124), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Research Centre for Toxic Compounds in the Environment Brno (RECETOX / MUNI), Faculty of Science Brno (SCI / MUNI), Masaryk University Brno (MUNI)-Masaryk University Brno (MUNI), Palacky University Olomouc, Flemish Institute for Technological Research (VITO), National Center for Biotechnology Information (NCBI), National Institutes of Health Bethesda, MD, USA (NIH), Chemotargets SL, GSFC University, Forschungs- und Beratungsinstitut Gefahrstoffe GmbH (FoBiG), Seven Past Nine, Vrije Universiteit Amsterdam Amsterdam (VU), Karolinska Institutet Stockholm, Misvik Biology, Heriot-Watt University Edinburgh (HWU), ELIXIR Hub Cambridge, Goethe University Frankfurt, Ideaconsult, Maastricht University Maastricht, ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), MetaboHUB-MetaToul, MetaboHUB-Génopole Toulouse Midi-Pyrénées Auzeville (GENOTOUL), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Faculté de Médecine, de pharmacie et d’Odonto-Stomatologie Bamako, Mali (FMPOS), Université de Bamako, University of Birmingham Birmingham, University of Tartu, AstraZeneca Cambridge, UK, Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Institut Français de Bioinformatique (IFB-CORE), Institut National de Recherche en Informatique et en Automatique (Inria)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Leibniz Institute of Plant Biochemistry (IPB), Innsbruck Medical University = Medizinische Universität Innsbruck (IMU), Universitat Rovira i Virgili, University of Oxford, Centre International de Recherche contre le Cancer - International Agency for Research on Cancer (CIRC - IARC), Organisation Mondiale de la Santé / World Health Organization Office Genève, Suisse (OMS / WHO), University of York York, UK, Universitat Pompeu Fabra Barcelona (UPF), National Technical University of Athens Athens (NTUA), Helmholtz Zentrum für Umweltforschung = Helmholtz Centre for Environmental Research (UFZ), Environmental Institute Kos, Uppsala University, Leiden Academic Center for Drug Research, United States Environmental Protection Agency Cincinnati, Universität Wien = University of Vienna, National Institute of Biology Ljubljana (NIB), This work received funding from the European Union’s Horizon 2020 research infrastrcuture programme via the OpenRiskNet project under grant agreement No. 731075.This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 681002 (EU-ToxRisk).This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 814572.SN acknowledges BMBF funding under grant number 031L0107.This work was supported by OBERON (https://oberon-4eu.comTest), a project funded by the European Union's Horizon 2020 research and innovation program under the grant agreement No. 825712.This work was supported by the European Union,'s Horizon 2020 research and innovation program HBM4EU, grant agreement No. 733032 (https://www.hbm4eu.euTest).Supported by the European Union’s Horizon 2020 programme under the Marie Skłodowska-Curie grant agreement No. 859891.Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article, and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer/World Health Organization.This work was supported by the European Union,'s Horizon 2020 research and innovation program HARMLESS, grant agreement No. 953183.This work was supported by the European Union,'s Horizon 2020 research and innovation program Gov4Nano, grant agreement No. 814401.This work was supported by the Swedish Fund for Research Without Animal Experiments under grant number N2020-0005.This work was supported by the European Union,'s Horizon 2020 research and innovation program NTS-EXPOSURE, Grant agreement ID: 896141.This work was supported by the European Union,'s LIFE program LIFE-APEX, Grant agreement ID: LIFE17 ENV/SK/000355.This study was funded by the German Environment Agency within the PHION project (grant number 3718 674150).The Data Readiness Group is supported, in this ELIXIR Community, by the H2020 Precision Toxicology project (H2020-EU 965406).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome ISA-InterMine project (208381/A/17/Z).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome FAIRsharing project (212930/Z/18/Z).This work received funding from the European Union’s Horizon 2020 research and innovation programme RiskGONE Project under grant agreement No. 814425.NR's research is funded by a Miguel Servet contract (CO19/00060) from Instituto de Salud Carlos III, cofinanced by the European Union.UM (Uni. of Tartu) is grateful for support to Ministry of Education and Research, Republic of Estonia through Estonian Research Council (grant number IUT34-14) and to European Union European Regional Development Fund through Foundation Archimedes (grant number TK143, Centre of Excellence in Molecular Cell Engineering).Development and Implementation of a Sustainable Modelling Platform for NanoInformatics.Linking LRI Ambit chemoinformatic system with the IUCLID substance database to support read-across of substance endpoint data and category formation.This work was supported by the French Ministry of Research and National Research Agency as part of the French MetaboHUB, the national metabolomics and fluxomics infrastructure (Grant ANR-INBS-0010).This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement GOLIATH No. 825489., ANR-11-INBS-0010,METABOHUB,Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation(2011), European Project: 681002,H2020,H2020-PHC-2015-single-stage_RTD,EU-ToxRisk(2016), European Project: 825712,H2020-EU.3.1.1. - Understanding health, wellbeing and disease,H2020-SC1-2018-Single-Stage-RTD,OBERON(2019), European Project: 733032,H2020,HBM4EU(2017), European Project: 814425,H2020,RiskGONE(2019), European Project: 825489,H2020,GOLIATH(2019)

المصدر: ISSN: 2046-1402 ; F1000Research ; https://pasteur.hal.science/pasteur-03680151Test ; F1000Research, 2021, 10, pp.1129. ⟨10.12688/f1000research.74502.1⟩.

مصطلحات موضوعية: Toxicology, ELIXIR, interoperability, FAIR, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], [SDV.TOX]Life Sciences [q-bio]/Toxicology

العلاقة: info:eu-repo/grantAgreement//681002/EU/An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century/EU-ToxRisk; info:eu-repo/grantAgreement//825712/EU/An integrative strategy of testing systems for identification of EDs related to metabolic disorders/OBERON; info:eu-repo/grantAgreement//733032/EU/European Human Biomonitoring Initiative/HBM4EU; info:eu-repo/grantAgreement//814425/EU/Risk Governance of Nanotechnology/RiskGONE; info:eu-repo/grantAgreement//825489/EU/Beating Goliath: Generation Of NoveL, Integrated and Internationally Harmonised Approaches for Testing Metabolism Disrupting Compounds/GOLIATH; pasteur-03680151; https://pasteur.hal.science/pasteur-03680151Test; https://pasteur.hal.science/pasteur-03680151/documentTest; https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

الإتاحة: https://doi.org/10.12688/f1000research.74502.1Test
https://pasteur.hal.science/pasteur-03680151Test
https://pasteur.hal.science/pasteur-03680151/documentTest
https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

المؤلفون: Martens, Marvin, Stierum, Rob, Schymanski, Emma, Evelo, Chris, Aalizadeh, Reza, Aladjov, Hristo, Arturi, Kasia, Audouze, Karine, Babica, Pavel, Berka, Karel, Bessems, Jos, Blaha, Ludek, Bolton, Evan, Cases, Montserrat, Damalas, Dimitrios, Dave, Kirtan, Dilger, Marco, Exner, Thomas, Geerke, Daan, Grafström, Roland, Gray, Alasdair, Hancock, John, Hollert, Henner, Jeliazkova, Nina, Jennen, Danyel, Jourdan, Fabien, Kahlem, Pascal, Klanova, Jana, Kleinjans, Jos, Kondic, Todor, Kone, Boï, Lynch, Iseult, Maran, Uko, Martinez Cuesta, Sergio, Ménager, Hervé, Neumann, Steffen, Nymark, Penny, Oberacher, Herbert, Ramirez, Noelia, Remy, Sylvie, Rocca-Serra, Philippe, Salek, Reza, Sallach, Brett, Sansone, Susanna-Assunta, Sanz, Ferran, Sarimveis, Haralambos, Sarntivijai, Sirarat, Schulze, Tobias, Slobodnik, Jaroslav, Spjuth, Ola, Tedds, Jonathan, Thomaidis, Nikolaos, Weber, Ralf, van Westen, Gerard, Wheelock, Craig, Williams, Antony, Witters, Hilda, Zdrazil, Barbara, Županič, Anže, Willighagen, Egon

المساهمون: Department of Bioinformatics, Maastricht University Medical Center (BiGCaT), The Netherlands Organisation for Applied Scientific Research (TNO), Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg Luxembourg, Maastricht Centre for Systems Biology, Maastricht University Medical Center (MaCSBio), National and Kapodistrian University of Athens (NKUA), Bulgarian Academy of Sciences (BAS), Swiss Federal Institute of Aquatic Science & Technology (EAWA), Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire (T3S - UMR_S 1124), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Research Centre for Toxic Compounds in the Environment Brno (RECETOX / MUNI), Faculty of Science Brno (SCI / MUNI), Masaryk University Brno (MUNI)-Masaryk University Brno (MUNI), Palacky University Olomouc, Flemish Institute for Technological Research (VITO), National Center for Biotechnology Information (NCBI), National Institutes of Health Bethesda, MD, USA (NIH), Chemotargets SL, GSFC University, Forschungs- und Beratungsinstitut Gefahrstoffe GmbH (FoBiG), Seven Past Nine, Vrije Universiteit Amsterdam Amsterdam (VU), Karolinska Institutet Stockholm, Misvik Biology, Heriot-Watt University Edinburgh (HWU), ELIXIR Hub Cambridge, Goethe University Frankfurt, Ideaconsult, Maastricht University Maastricht, ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), MetaboHUB-MetaToul, MetaboHUB-Génopole Toulouse Midi-Pyrénées Auzeville (GENOTOUL), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Faculté de Médecine, de pharmacie et d’Odonto-Stomatologie Bamako, Mali (FMPOS), Université de Bamako, University of Birmingham Birmingham, University of Tartu, AstraZeneca Cambridge, UK, Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Institut Français de Bioinformatique (IFB-CORE), Institut National de Recherche en Informatique et en Automatique (Inria)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Leibniz Institute of Plant Biochemistry (IPB), Innsbruck Medical University = Medizinische Universität Innsbruck (IMU), Universitat Rovira i Virgili, University of Oxford, Centre International de Recherche contre le Cancer - International Agency for Research on Cancer (CIRC - IARC), Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), University of York York, UK, Universitat Pompeu Fabra Barcelona (UPF), National Technical University of Athens Athens (NTUA), Helmholtz Zentrum für Umweltforschung = Helmholtz Centre for Environmental Research (UFZ), Environmental Institute Kos, Uppsala University, Leiden Academic Center for Drug Research, United States Environmental Protection Agency Cincinnati, University of Vienna Vienna, National Institute of Biology Ljubljana (NIB), This work received funding from the European Union’s Horizon 2020 research infrastrcuture programme via the OpenRiskNet project under grant agreement No. 731075.This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 681002 (EU-ToxRisk).This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 814572.SN acknowledges BMBF funding under grant number 031L0107.This work was supported by OBERON (https://oberon-4eu.comTest), a project funded by the European Union's Horizon 2020 research and innovation program under the grant agreement No. 825712.This work was supported by the European Union,'s Horizon 2020 research and innovation program HBM4EU, grant agreement No. 733032 (https://www.hbm4eu.euTest).Supported by the European Union’s Horizon 2020 programme under the Marie Skłodowska-Curie grant agreement No. 859891.Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article, and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer/World Health Organization.This work was supported by the European Union,'s Horizon 2020 research and innovation program HARMLESS, grant agreement No. 953183.This work was supported by the European Union,'s Horizon 2020 research and innovation program Gov4Nano, grant agreement No. 814401.This work was supported by the Swedish Fund for Research Without Animal Experiments under grant number N2020-0005.This work was supported by the European Union,'s Horizon 2020 research and innovation program NTS-EXPOSURE, Grant agreement ID: 896141.This work was supported by the European Union,'s LIFE program LIFE-APEX, Grant agreement ID: LIFE17 ENV/SK/000355.This study was funded by the German Environment Agency within the PHION project (grant number 3718 674150).The Data Readiness Group is supported, in this ELIXIR Community, by the H2020 Precision Toxicology project (H2020-EU 965406).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome ISA-InterMine project (208381/A/17/Z).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome FAIRsharing project (212930/Z/18/Z).This work received funding from the European Union’s Horizon 2020 research and innovation programme RiskGONE Project under grant agreement No. 814425.NR's research is funded by a Miguel Servet contract (CO19/00060) from Instituto de Salud Carlos III, cofinanced by the European Union.UM (Uni. of Tartu) is grateful for support to Ministry of Education and Research, Republic of Estonia through Estonian Research Council (grant number IUT34-14) and to European Union European Regional Development Fund through Foundation Archimedes (grant number TK143, Centre of Excellence in Molecular Cell Engineering).Development and Implementation of a Sustainable Modelling Platform for NanoInformatics.Linking LRI Ambit chemoinformatic system with the IUCLID substance database to support read-across of substance endpoint data and category formation.This work was supported by the French Ministry of Research and National Research Agency as part of the French MetaboHUB, the national metabolomics and fluxomics infrastructure (Grant ANR-INBS-0010).This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement GOLIATH No. 825489., ANR-11-INBS-0010,METABOHUB,Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation(2011), European Project: 681002,H2020,H2020-PHC-2015-single-stage_RTD,EU-ToxRisk(2016), European Project: 825712,H2020-EU.3.1.1. - Understanding health, wellbeing and disease,H2020-SC1-2018-Single-Stage-RTD,OBERON(2019), European Project: 733032,H2020,HBM4EU(2017), European Project: 814425,H2020,RiskGONE(2019), European Project: 825489,H2020,GOLIATH(2019)

المصدر: ISSN: 2046-1402 ; F1000Research ; https://pasteur.hal.science/pasteur-03680151Test ; F1000Research, 2021, 10, pp.1129. ⟨10.12688/f1000research.74502.1⟩.

مصطلحات موضوعية: Toxicology, ELIXIR, interoperability, FAIR, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], [SDV.TOX]Life Sciences [q-bio]/Toxicology

العلاقة: info:eu-repo/grantAgreement//681002/EU/An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century/EU-ToxRisk; info:eu-repo/grantAgreement//825712/EU/An integrative strategy of testing systems for identification of EDs related to metabolic disorders/OBERON; info:eu-repo/grantAgreement//733032/EU/European Human Biomonitoring Initiative/HBM4EU; info:eu-repo/grantAgreement//814425/EU/Risk Governance of Nanotechnology/RiskGONE; info:eu-repo/grantAgreement//825489/EU/Beating Goliath: Generation Of NoveL, Integrated and Internationally Harmonised Approaches for Testing Metabolism Disrupting Compounds/GOLIATH; pasteur-03680151; https://pasteur.hal.science/pasteur-03680151Test; https://pasteur.hal.science/pasteur-03680151/documentTest; https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

الإتاحة: https://doi.org/10.12688/f1000research.74502.1Test
https://pasteur.hal.science/pasteur-03680151Test
https://pasteur.hal.science/pasteur-03680151/documentTest
https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

المؤلفون: Martens, Marvin, Stierum, Rob, Schymanski, Emma, Evelo, Chris, Aalizadeh, Reza, Aladjov, Hristo, Arturi, Kasia, Audouze, Karine, Babica, Pavel, Berka, Karel, Bessems, Jos, Blaha, Ludek, Bolton, Evan, Cases, Montserrat, Damalas, Dimitrios, Dave, Kirtan, Dilger, Marco, Exner, Thomas, Geerke, Daan, Grafström, Roland, Gray, Alasdair, Hancock, John, Hollert, Henner, Jeliazkova, Nina, Jennen, Danyel, Jourdan, Fabien, Kahlem, Pascal, Klanova, Jana, Kleinjans, Jos, Kondic, Todor, Kone, Boï, Lynch, Iseult, Maran, Uko, Martinez Cuesta, Sergio, Ménager, Hervé, Neumann, Steffen, Nymark, Penny, Oberacher, Herbert, Ramirez, Noelia, Remy, Sylvie, Rocca-Serra, Philippe, Salek, Reza, Sallach, Brett, Sansone, Susanna-Assunta, Sanz, Ferran, Sarimveis, Haralambos, Sarntivijai, Sirarat, Schulze, Tobias, Slobodnik, Jaroslav, Spjuth, Ola, Tedds, Jonathan, Thomaidis, Nikolaos, Weber, Ralf, van Westen, Gerard, Wheelock, Craig, Williams, Antony, Witters, Hilda, Zdrazil, Barbara, Županič, Anže, Willighagen, Egon

المساهمون: Department of Bioinformatics, Maastricht University Medical Center (BiGCaT), The Netherlands Organisation for Applied Scientific Research (TNO), Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg Luxembourg, Maastricht Centre for Systems Biology, Maastricht University Medical Center (MaCSBio), National and Kapodistrian University of Athens (NKUA), Bulgarian Academy of Sciences (BAS), Swiss Federal Institute of Aquatic Science & Technology (EAWA), Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire (T3S - UMR_S 1124), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Research Centre for Toxic Compounds in the Environment Brno (RECETOX / MUNI), Faculty of Science Brno (SCI / MUNI), Masaryk University Brno (MUNI)-Masaryk University Brno (MUNI), Palacky University Olomouc, Flemish Institute for Technological Research (VITO), National Center for Biotechnology Information (NCBI), National Institutes of Health Bethesda, MD, USA (NIH), Chemotargets SL, GSFC University, Forschungs- und Beratungsinstitut Gefahrstoffe GmbH (FoBiG), Seven Past Nine, Vrije Universiteit Amsterdam Amsterdam (VU), Karolinska Institutet Stockholm, Misvik Biology, Heriot-Watt University Edinburgh (HWU), ELIXIR Hub Cambridge, Goethe-University Frankfurt am Main, Ideaconsult, Maastricht University Maastricht, ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), MetaboHUB-MetaToul, MetaboHUB-Génopole Toulouse Midi-Pyrénées Auzeville (GENOTOUL), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Faculté de Médecine, de pharmacie et d’Odonto-Stomatologie Bamako, Mali (FMPOS), Université de Bamako, University of Birmingham Birmingham, University of Tartu, AstraZeneca Cambridge, UK, Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Institut Français de Bioinformatique (IFB-CORE), Institut National de Recherche en Informatique et en Automatique (Inria)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Leibniz Institute of Plant Biochemistry (IPB), Innsbruck Medical University = Medizinische Universität Innsbruck (IMU), Universitat Rovira i Virgili, University of Oxford, Centre International de Recherche contre le Cancer - International Agency for Research on Cancer (CIRC - IARC), Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), University of York York, UK, Universitat Pompeu Fabra Barcelona (UPF), National Technical University of Athens Athens (NTUA), Helmholtz Zentrum für Umweltforschung = Helmholtz Centre for Environmental Research (UFZ), Environmental Institute Kos, Uppsala University, Leiden Academic Center for Drug Research, United States Environmental Protection Agency Cincinnati, University of Vienna Vienna, National Institute of Biology Ljubljana (NIB), This work received funding from the European Union’s Horizon 2020 research infrastrcuture programme via the OpenRiskNet project under grant agreement No. 731075.This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 681002 (EU-ToxRisk).This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 814572.SN acknowledges BMBF funding under grant number 031L0107.This work was supported by OBERON (https://oberon-4eu.comTest), a project funded by the European Union's Horizon 2020 research and innovation program under the grant agreement No. 825712.This work was supported by the European Union,'s Horizon 2020 research and innovation program HBM4EU, grant agreement No. 733032 (https://www.hbm4eu.euTest).Supported by the European Union’s Horizon 2020 programme under the Marie Skłodowska-Curie grant agreement No. 859891.Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article, and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer/World Health Organization.This work was supported by the European Union,'s Horizon 2020 research and innovation program HARMLESS, grant agreement No. 953183.This work was supported by the European Union,'s Horizon 2020 research and innovation program Gov4Nano, grant agreement No. 814401.This work was supported by the Swedish Fund for Research Without Animal Experiments under grant number N2020-0005.This work was supported by the European Union,'s Horizon 2020 research and innovation program NTS-EXPOSURE, Grant agreement ID: 896141.This work was supported by the European Union,'s LIFE program LIFE-APEX, Grant agreement ID: LIFE17 ENV/SK/000355.This study was funded by the German Environment Agency within the PHION project (grant number 3718 674150).The Data Readiness Group is supported, in this ELIXIR Community, by the H2020 Precision Toxicology project (H2020-EU 965406).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome ISA-InterMine project (208381/A/17/Z).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome FAIRsharing project (212930/Z/18/Z).This work received funding from the European Union’s Horizon 2020 research and innovation programme RiskGONE Project under grant agreement No. 814425.NR's research is funded by a Miguel Servet contract (CO19/00060) from Instituto de Salud Carlos III, cofinanced by the European Union.UM (Uni. of Tartu) is grateful for support to Ministry of Education and Research, Republic of Estonia through Estonian Research Council (grant number IUT34-14) and to European Union European Regional Development Fund through Foundation Archimedes (grant number TK143, Centre of Excellence in Molecular Cell Engineering).Development and Implementation of a Sustainable Modelling Platform for NanoInformatics.Linking LRI Ambit chemoinformatic system with the IUCLID substance database to support read-across of substance endpoint data and category formation.This work was supported by the French Ministry of Research and National Research Agency as part of the French MetaboHUB, the national metabolomics and fluxomics infrastructure (Grant ANR-INBS-0010).This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement GOLIATH No. 825489., ANR-11-INBS-0010,METABOHUB,Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation(2011), European Project: 681002,H2020,H2020-PHC-2015-single-stage_RTD,EU-ToxRisk(2016), European Project: 825712,H2020-EU.3.1.1. - Understanding health, wellbeing and disease,H2020-SC1-2018-Single-Stage-RTD,OBERON(2019), European Project: 733032,H2020,HBM4EU(2017), European Project: 814425,RiskGONE, European Project: 825489,H2020,GOLIATH(2019)

المصدر: ISSN: 2046-1402 ; F1000Research ; https://pasteur.hal.science/pasteur-03680151Test ; F1000Research, 2021, 10, pp.1129. ⟨10.12688/f1000research.74502.1⟩.

مصطلحات موضوعية: Toxicology, ELIXIR, interoperability, FAIR, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], [SDV.TOX]Life Sciences [q-bio]/Toxicology

العلاقة: info:eu-repo/grantAgreement//681002/EU/An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century/EU-ToxRisk; info:eu-repo/grantAgreement//825712/EU/An integrative strategy of testing systems for identification of EDs related to metabolic disorders/OBERON; info:eu-repo/grantAgreement//733032/EU/European Human Biomonitoring Initiative/HBM4EU; info:eu-repo/grantAgreement//814425/EU/Risk Governance of Nanotechnology/RiskGONE; info:eu-repo/grantAgreement//825489/EU/Beating Goliath: Generation Of NoveL, Integrated and Internationally Harmonised Approaches for Testing Metabolism Disrupting Compounds/GOLIATH; pasteur-03680151; https://pasteur.hal.science/pasteur-03680151Test; https://pasteur.hal.science/pasteur-03680151/documentTest; https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

الإتاحة: https://doi.org/10.12688/f1000research.74502.1Test
https://pasteur.hal.science/pasteur-03680151Test
https://pasteur.hal.science/pasteur-03680151/documentTest
https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

المؤلفون: Martens, Marvin, Stierum, Rob, Schymanski, Emma, Evelo, Chris, Aalizadeh, Reza, Aladjov, Hristo, Arturi, Kasia, Audouze, Karine, Babica, Pavel, Berka, Karel, Bessems, Jos, Blaha, Ludek, Bolton, Evan, Cases, Montserrat, Damalas, Dimitrios, Dave, Kirtan, Dilger, Marco, Exner, Thomas, Geerke, Daan, Grafström, Roland, Gray, Alasdair, Hancock, John, Hollert, Henner, Jeliazkova, Nina, Jennen, Danyel, Jourdan, Fabien, Kahlem, Pascal, Klanova, Jana, Kleinjans, Jos, Kondic, Todor, Kone, Boï, Lynch, Iseult, Maran, Uko, Martinez Cuesta, Sergio, Ménager, Hervé, Neumann, Steffen, Nymark, Penny, Oberacher, Herbert, Ramirez, Noelia, Remy, Sylvie, Rocca-Serra, Philippe, Salek, Reza, Sallach, Brett, Sansone, Susanna-Assunta, Sanz, Ferran, Sarimveis, Haralambos, Sarntivijai, Sirarat, Schulze, Tobias, Slobodnik, Jaroslav, Spjuth, Ola, Tedds, Jonathan, Thomaidis, Nikolaos, Weber, Ralf, van Westen, Gerard, Wheelock, Craig, Williams, Antony, Witters, Hilda, Zdrazil, Barbara, Županič, Anže, Willighagen, Egon

المساهمون: Department of Bioinformatics, Maastricht University Medical Center (BiGCaT), The Netherlands Organisation for Applied Scientific Research (TNO), Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg Luxembourg, Maastricht Centre for Systems Biology, Maastricht University Medical Center (MaCSBio), National and Kapodistrian University of Athens (NKUA), Bulgarian Academy of Sciences (BAS), Swiss Federal Institute of Aquatic Science & Technology (EAWA), Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire (T3S - UMR_S 1124), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Research Centre for Toxic Compounds in the Environment Brno (RECETOX / MUNI), Faculty of Science Brno (SCI / MUNI), Masaryk University Brno (MUNI)-Masaryk University Brno (MUNI), Palacky University Olomouc, Flemish Institute for Technological Research (VITO), National Center for Biotechnology Information (NCBI), National Institutes of Health Bethesda, MD, USA (NIH), Chemotargets SL, GSFC University, Forschungs- und Beratungsinstitut Gefahrstoffe GmbH (FoBiG), Seven Past Nine, Vrije Universiteit Amsterdam Amsterdam (VU), Karolinska Institutet Stockholm, Misvik Biology, Heriot-Watt University Edinburgh (HWU), ELIXIR Hub Cambridge, Goethe University Frankfurt, Ideaconsult, Maastricht University Maastricht, ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), MetaboHUB-MetaToul, MetaboHUB-Génopole Toulouse Midi-Pyrénées Auzeville (GENOTOUL), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Faculté de Médecine, de pharmacie et d’Odonto-Stomatologie Bamako, Mali (FMPOS), Université de Bamako, University of Birmingham Birmingham, University of Tartu, AstraZeneca Cambridge, UK, Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Institut Français de Bioinformatique (IFB-CORE), Institut National de Recherche en Informatique et en Automatique (Inria)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Leibniz Institute of Plant Biochemistry (IPB), Innsbruck Medical University = Medizinische Universität Innsbruck (IMU), Universitat Rovira i Virgili, University of Oxford, Centre International de Recherche contre le Cancer - International Agency for Research on Cancer (CIRC - IARC), Organisation Mondiale de la Santé / World Health Organization Office Genève, Suisse (OMS / WHO), University of York York, UK, Universitat Pompeu Fabra Barcelona (UPF), National Technical University of Athens Athens (NTUA), Helmholtz Zentrum für Umweltforschung = Helmholtz Centre for Environmental Research (UFZ), Environmental Institute Kos, Uppsala University, Leiden Academic Center for Drug Research, United States Environmental Protection Agency Cincinnati, Universität Wien = University of Vienna, National Institute of Biology Ljubljana (NIB), This work received funding from the European Union’s Horizon 2020 research infrastrcuture programme via the OpenRiskNet project under grant agreement No. 731075.This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 681002 (EU-ToxRisk).This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 814572.SN acknowledges BMBF funding under grant number 031L0107.This work was supported by OBERON (https://oberon-4eu.comTest), a project funded by the European Union's Horizon 2020 research and innovation program under the grant agreement No. 825712.This work was supported by the European Union,'s Horizon 2020 research and innovation program HBM4EU, grant agreement No. 733032 (https://www.hbm4eu.euTest).Supported by the European Union’s Horizon 2020 programme under the Marie Skłodowska-Curie grant agreement No. 859891.Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article, and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer/World Health Organization.This work was supported by the European Union,'s Horizon 2020 research and innovation program HARMLESS, grant agreement No. 953183.This work was supported by the European Union,'s Horizon 2020 research and innovation program Gov4Nano, grant agreement No. 814401.This work was supported by the Swedish Fund for Research Without Animal Experiments under grant number N2020-0005.This work was supported by the European Union,'s Horizon 2020 research and innovation program NTS-EXPOSURE, Grant agreement ID: 896141.This work was supported by the European Union,'s LIFE program LIFE-APEX, Grant agreement ID: LIFE17 ENV/SK/000355.This study was funded by the German Environment Agency within the PHION project (grant number 3718 674150).The Data Readiness Group is supported, in this ELIXIR Community, by the H2020 Precision Toxicology project (H2020-EU 965406).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome ISA-InterMine project (208381/A/17/Z).The Data Readiness Group is supported, in this ELIXIR Community, by the Wellcome FAIRsharing project (212930/Z/18/Z).This work received funding from the European Union’s Horizon 2020 research and innovation programme RiskGONE Project under grant agreement No. 814425.NR's research is funded by a Miguel Servet contract (CO19/00060) from Instituto de Salud Carlos III, cofinanced by the European Union.UM (Uni. of Tartu) is grateful for support to Ministry of Education and Research, Republic of Estonia through Estonian Research Council (grant number IUT34-14) and to European Union European Regional Development Fund through Foundation Archimedes (grant number TK143, Centre of Excellence in Molecular Cell Engineering).Development and Implementation of a Sustainable Modelling Platform for NanoInformatics.Linking LRI Ambit chemoinformatic system with the IUCLID substance database to support read-across of substance endpoint data and category formation.This work was supported by the French Ministry of Research and National Research Agency as part of the French MetaboHUB, the national metabolomics and fluxomics infrastructure (Grant ANR-INBS-0010).This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement GOLIATH No. 825489., ANR-11-INBS-0010,METABOHUB,Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation(2011), European Project: 681002,H2020,H2020-PHC-2015-single-stage_RTD,EU-ToxRisk(2016), European Project: 825712,H2020-EU.3.1.1. - Understanding health, wellbeing and disease,H2020-SC1-2018-Single-Stage-RTD,OBERON(2019), European Project: 733032,H2020,HBM4EU(2017), European Project: 814425,H2020,RiskGONE(2019), European Project: 825489,H2020,GOLIATH(2019)

المصدر: ISSN: 2046-1402 ; F1000Research ; https://pasteur.hal.science/pasteur-03680151Test ; F1000Research, 2021, 10, pp.1129. ⟨10.12688/f1000research.74502.1⟩.

مصطلحات موضوعية: Toxicology, ELIXIR, interoperability, FAIR, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], [SDV.TOX]Life Sciences [q-bio]/Toxicology

العلاقة: info:eu-repo/grantAgreement//681002/EU/An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century/EU-ToxRisk; info:eu-repo/grantAgreement//825712/EU/An integrative strategy of testing systems for identification of EDs related to metabolic disorders/OBERON; info:eu-repo/grantAgreement//733032/EU/European Human Biomonitoring Initiative/HBM4EU; info:eu-repo/grantAgreement//814425/EU/Risk Governance of Nanotechnology/RiskGONE; info:eu-repo/grantAgreement//825489/EU/Beating Goliath: Generation Of NoveL, Integrated and Internationally Harmonised Approaches for Testing Metabolism Disrupting Compounds/GOLIATH; pasteur-03680151; https://pasteur.hal.science/pasteur-03680151Test; https://pasteur.hal.science/pasteur-03680151/documentTest; https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

الإتاحة: https://doi.org/10.12688/f1000research.74502.1Test
https://pasteur.hal.science/pasteur-03680151Test
https://pasteur.hal.science/pasteur-03680151/documentTest
https://pasteur.hal.science/pasteur-03680151/file/f61cccea-d930-4df8-b15d-88449bbc3323_74502_-_marvin_martens.pdfTest

المؤلفون: van Rijswijk, M., Beirnaert, C., Caron, C., Cascante, M., Dominguez, V., Dunn, W. B., Ebbels, T. M. D., Giacomoni, Franck, Gonzalez-Beltran, A., Hankemeier, T., Haug, K., Izquierdo-Garcia, J. L., Jimenez, R. C., Jourdan, Fabien, Kale, N., Klapa, M. I., Kohlbacher, O., Koort, K., Kultima, K., Le Corguille, G., Moschonas, N. K., Neumann, S., O'Donovan, C., Reczko, M., Rocca-Serra, P., Rosato, A., Salek, R. M., Sansone, S. A., Satagopam, V., Schober, D., Shimmo, R., Spicer, R. A., Spjuth, O., Thévenot, Etienne A, Viant, M. R., Weber, R. J. M., Willighagen, E. L., Zanetti, G., Steinbeck, C.

المساهمون: Dutch Techcentre for Life Sciences Utrecht, Netherlands Metabolomics Centre, Department of Mathematics and Computer Science, ADReM, University of Antwerp (UA), French Institute of Bioinformatics (ELIXIR-FR), Department of Biochemistry and Molecular Biomedicine, Faculty of Science and Technology, Biochemistry and Molecular Biology, University of Barcelona, Birmingham Metabolomics Training Centre, University of Birmingham, Department of Surgery and Cancer, Imperial College London, Unité de Nutrition Humaine (UNH), Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne 2017-2020 (UCA 2017-2020 ), MetaboHUB, Oxford e-Research Centre, University of Oxford, Leiden Academic Centre for Drug Research (LACDR), Universiteit Leiden = Leiden University, European Bioinformatics Institute Hinxton (EMBL-EBI), EMBL Heidelberg, Centro Nacional de Investigaciones Cardiovasculares, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), ELIXIR Hub Cambridge, Métabolisme et Xénobiotiques (ToxAlim-MeX), ToxAlim (ToxAlim), Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT), Forth ICE-HT, Institute of Chemical Engineering Sciences, Foundation for Research and Technology - Hellas (FORTH), Max Planck Institute for Developmental Biology, Max-Planck-Gesellschaft, Department of Computer Science, Duke University Durham, Center for Bioinformatics, University of Tübingen, The Centre of Excellence in Neural and Behavioural Sciences, Tallinn University, School of Natural Sciences and Health, Department of Medical Sciences (University of Miyasaki), University of Miyasaki, ABiMS - Informatique et bioinformatique = Analysis and Bioinformatics for Marine Science (ABIMS), Fédération de recherche de Roscoff (FR2424), Station biologique de Roscoff = Roscoff Marine Station (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Station biologique de Roscoff = Roscoff Marine Station (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS), Instituto de Ciencias Biologicas Minas Gerais (ICB), Universidade Federal de Minas Gerais = Federal University of Minas Gerais Belo Horizonte, Brazil (UFMG), University of Patras, Department of Stress and Developmental Biology, Leibniz Institute of Plant Biochemistry (IPB), BSRC "Alexander Fleming", Magnetic Resonance Center/Interuniversity Consortium of Magnetic Resonance Metalloproteins, Università degli Studi di Firenze = University of Florence = Université de Florence (UniFI), Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg Luxembourg, Université du Luxembourg (Uni.lu), Department of Pharmaceutical Biosciences, Uppsala University, Laboratoire Sciences des Données et de la Décision (CEA, LIST) (LS2D (CEA, LIST)), Département Métrologie Instrumentation & Information (CEA, LIST) (DM2I (CEA, LIST)), Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Department of Bioinformatics, BiGCaT, Maastricht University Maastricht, NUTRIM, Data-Intensive Computing, CRS4 Bioinformat, Friedrich-Schiller-Universität = Friedrich Schiller University Jena Jena, Germany, ANR-11-INBS-0010,METABOHUB,Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation(2011), European Project: 654241,H2020,H2020-EINFRA-2014-2,PhenoMeNal(2015)

المصدر: ISSN: 2046-1402 ; F1000Research ; https://hal.science/hal-01630635Test ; F1000Research, 2017, 6 (Version 2), ⟨10.12688/f1000research.12342.2⟩ ; https://f1000research.comTest/.

مصطلحات موضوعية: bioinformatics infrastructure, cloud computing, computational workflows, data standards, databases, metabolomics, multi-omics approaches, training, signal processing, statistical analysis, infrastructure en ligne, analyse métabolomique, pipeline, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], [CHIM.ANAL]Chemical Sciences/Analytical chemistry, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], [INFO.INFO-DL]Computer Science [cs]/Digital Libraries [cs.DL]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29043062; info:eu-repo/grantAgreement//654241/EU/PhenoMeNal: A comprehensive and standardised e-infrastructure for analysing medical metabolic phenotype data/PhenoMeNal; hal-01630635; https://hal.science/hal-01630635Test; https://hal.science/hal-01630635/documentTest; https://hal.science/hal-01630635/file/article_MerlijnvanRijswijk_reviewreport.pdfTest; PRODINRA: 411087; PUBMED: 29043062

الإتاحة: https://doi.org/10.12688/f1000research.12342.2Test
https://hal.science/hal-01630635Test
https://hal.science/hal-01630635/documentTest
https://hal.science/hal-01630635/file/article_MerlijnvanRijswijk_reviewreport.pdfTest