دورية أكاديمية
Prolonged postoperative cerebral oxygen desaturation after cardiac surgery: A prospective observational study.
| العنوان: | Prolonged postoperative cerebral oxygen desaturation after cardiac surgery: A prospective observational study. |
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| المؤلفون: | Cioccari, Luca, Bitker, Laurent, Toh, Lisa, Hacking, Douglas, Cutuli, Salvatore L, Osawa, Eduardo A, Yanase, Fumitaka, Naorungroj, Thummaporn, Luethi, Nora, Michalopoulos, Adrian, Woo, Shanan, Wang, Judy, Eastwood, Glenn M, Weinberg, Laurence, Bellomo, Rinaldo |
| المصدر: | Cioccari, Luca; Bitker, Laurent; Toh, Lisa; Hacking, Douglas; Cutuli, Salvatore L; Osawa, Eduardo A; Yanase, Fumitaka; Naorungroj, Thummaporn; Luethi, Nora; Michalopoulos, Adrian; Woo, Shanan; Wang, Judy; Eastwood, Glenn M; Weinberg, Laurence; Bellomo, Rinaldo (2021). Prolonged postoperative cerebral oxygen desaturation after cardiac surgery: A prospective observational study. European journal of anaesthesiology, 38(9), pp. 966-974. European Society of Anaesthesiology 10.1097/EJA.0000000000001391 |
| بيانات النشر: | European Society of Anaesthesiology |
| سنة النشر: | 2021 |
| المجموعة: | BORIS (Bern Open Repository and Information System, University of Bern) |
| مصطلحات موضوعية: | 610 Medicine & health |
| الوصف: | BACKGROUND Near-infrared spectroscopy (NIRS) is used routinely to monitor cerebral tissue oxygen saturation (SctO2) during cardiopulmonary bypass (CPB) but is rarely employed outside the operating room. Previous studies indicate that patients are at risk of postoperative cerebral oxygen desaturation after cardiac surgery. OBJECTIVES We aimed to assess perioperative and postoperative changes in NIRS-derived SctO2 in cardiac surgery patients. DESIGN Prospective observational study. SETTING The study was conducted in a tertiary referral university hospital in Australia from December 2017 to December 2018. PATIENTS We studied 34 adult patients (70.6% men) undergoing cardiac surgery requiring CPB and a reference group of 36 patients undergoing noncardiac surgical procedures under general anaesthesia. MAIN OUTCOME MEASURES We measured SctO2 at baseline, during and after surgery, and then once daily until hospital discharge, for a maximum of 7 days. We used multivariate linear mixed-effects modelling to adjust for all relevant imbalances between the two groups. RESULTS In the cardiac surgery group, SctO2 was 63.7% [95% confidence interval (CI), 62.0 to 65.5] at baseline and 61.0% (95% CI, 59.1 to 62.9, P = 0.01) on arrival in the ICU. From day 2 to day 7 after cardiac surgery, SctO2 progressively declined. At hospital discharge, SctO2 was significantly lower than baseline, at 53.5% (95% CI, 51.8 to 55.2, P < 0.001). In the reference group, postoperative SctO2 was not significantly different from baseline. On multivariable analysis, cardiac surgery, peripheral vascular disease and time since the operation were associated with greater cerebral desaturation, whereas higher haemoglobin concentrations were associated with slightly better cerebral oxygenation. CONCLUSION After cardiac surgery on CPB, but not after noncardiac surgery, most patients experience prolonged cerebral desaturation. Such postoperative desaturation remained unresolved 7 days after surgery. The underlying mechanisms and time to resolution of such ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://boris.unibe.ch/148384Test/ |
| الإتاحة: | https://doi.org/10.1097/EJA.0000000000001391Test https://boris.unibe.ch/148384/1/2020%20-%20Cioccari%20-%20%20Eur%20J%20Anaesthesiol%20-%20PMID%2033186311.pdfTest https://boris.unibe.ch/148384Test/ |
| حقوق: | info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsbas.1010ECDB |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |