Occupational asthma due to heated polypropylene
| العنوان: | Occupational asthma due to heated polypropylene |
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| المؤلفون: | Malo, Jl, Cartier, A., Pineault, L., Martin Dugas, Desjardins, A. |
| المصدر: | Web of Science |
| بيانات النشر: | European Respiratory Society (ERS), 1994. |
| سنة النشر: | 1994 |
| مصطلحات موضوعية: | Pulmonary and Respiratory Medicine |
| الوصف: | A 35 year-old nonatopic woman was referred to the hospital for possible work-related asthma. She had worked as an operator, at a plant producing polypropylene bags, for the previous four yrs. Her main complaint was a productive cough with dyspnoea and wheezing, as well as rhinitis over the past 3 yrs. She had been absent from work for 6 months on maternity leave, and had improved greatly. She was on a beta 2-adrenergic agent and had to take it at least four times daily. Baseline spirometry whilst at work showed marked airflow obstruction (forced expiratory volume in one second (FEV1) of 43% predicted (pred). After two months away from work FEV1 improved to 89% pred; provocative concentration of histamine causing a 25% fall in FEV1 (PC20) was 3.6 mg.ml-1 (mild airway hyperresponsiveness). Return to work resulted in a marked deterioration in FEV1, and serial peak expiratory flow (PEFR) values. PC20 was 0.11 mg.ml-1 (severe airway hyperresponsiveness) one week after she had returned to work. Specific inhalation challenges with polypropylene heated to 250 degrees C resulted in a late asthmatic reaction. As formaldehyde is one of the degradation products of heating polypropylene, we exposed her to it for up to 2 h, but we elicited no bronchospastic reaction. We conclude that heated polypropylene should be listed as one of the agents that causes occupational asthma. |
| تدمد: | 1399-3003 0903-1936 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39c186ebccd03dae8dd8a4cc41d70dbTest https://doi.org/10.1183/09031936.94.07020415Test |
| رقم الانضمام: | edsair.doi.dedup.....c39c186ebccd03dae8dd8a4cc41d70db |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13993003 09031936 |
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