دورية أكاديمية
People living with undiagnosed HIV infection and a low CD4 count: Estimates from surveillance data, Italy, 2012 to 2014
| العنوان: | People living with undiagnosed HIV infection and a low CD4 count: Estimates from surveillance data, Italy, 2012 to 2014 |
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| المؤلفون: | Regine, Vincenza, Dorrucci, Maria, Pezzotti, Patrizio, Mammone, Alessia, Quinten, Chantal, Pharris, Anastasia, Suligoi, Barbara, Di Giacomo, Manuela, Faggioni, Viviana, Scancella, Luigi, Locuratolo, Francesco, Cauzillo, Gabriella, Mignuoli, Anna Domenica, Chirico, Daniele Giuseppe, Borgia, Guglielmo, Massimiliani, Erika, Gallo, Tolinda, Braida, Cinzia, Puro, Vincenzo, Scognamiglio, Paola, Icardi, Giancarlo, Lai, Piero Luigi, Gramegna, Maria, Coppola, Liliana, Piatti, Alessandra, Rosa, Annamaria, Cereda, Danilo, Filippetti, Fabio, Prozzo, Alessandra, Pasqualini, Chiara, Mian, Peter, Moling, Oswald, Pagani, Leonardo, Lanzafame, Paolo, Collini, Lucia, Bassetti, Danila, Chironna, Maria, Palmas, Maria Antonietta, Dardanoni, Gabriella, Voller, Fabio, Puglia, Monia, Pecori, Lucia, Tosti, Anna, Papili, Rita, Ruffier, Mauro, Verardo, Marina Giulia, Echarlod, Elisa Francesca, Amoroso, Saveria, Russo, Francesca, Da Re, Filippo |
| المساهمون: | Regine, Vincenza, Dorrucci, Maria, Pezzotti, Patrizio, Mammone, Alessia, Quinten, Chantal, Pharris, Anastasia, Suligoi, Barbara, Di Giacomo, Manuela, Faggioni, Viviana, Scancella, Luigi, Locuratolo, Francesco, Cauzillo, Gabriella, Mignuoli, Anna Domenica, Chirico, Daniele Giuseppe, Borgia, Guglielmo, Massimiliani, Erika, Gallo, Tolinda, Braida, Cinzia, Puro, Vincenzo, Scognamiglio, Paola, Icardi, Giancarlo, Lai, Piero Luigi, Gramegna, Maria, Coppola, Liliana, Piatti, Alessandra, Rosa, Annamaria, Cereda, Danilo, Filippetti, Fabio, Prozzo, Alessandra, Pasqualini, Chiara, Mian, Peter, Moling, Oswald, Pagani, Leonardo, Lanzafame, Paolo, Collini, Lucia, Bassetti, Danila, Chironna, Maria, Palmas, Maria Antonietta, Dardanoni, Gabriella, Voller, Fabio, Puglia, Monia, Pecori, Lucia, Tosti, Anna, Papili, Rita, Ruffier, Mauro, Verardo, Marina Giulia, Echarlod, Elisa Francesca, Amoroso, Saveria, Russo, Francesca, Da Re, Filippo |
| بيانات النشر: | European Centre for Disease Prevention and Control (ECDC) TOMTEBODAVAGEN 11A, STOCKHOLM, 171 83, SWEDEN |
| سنة النشر: | 2018 |
| المجموعة: | Università degli Studi di Genova: CINECA IRIS |
| مصطلحات موضوعية: | HIV infection, low CD4 count, modelling, surveillance data, undiagnosed HIV infection, Epidemiology, Public Health, Environmental and Occupational Health, Virology |
| الوصف: | Background and aims: Late HIV diagnosis is associated with onward HIV transmission, higher morbidity, mortality and healthcare costs. In Italy, more than half of people living with HIV were diagnosed late during the last decade, with a CD4 count < 350 cells/mm3 at diagnosis. We aimed to determine the number and characteristics of people living with undiagnosed HIV infection and low CD4 counts in Italy. Methods: Data on newly reported HIV diagnoses from 2012 –2014 were obtained from the national HIV surveillance system. We used the European Centre for Disease Prevention and Control HIV modelling tool to calculate the undiagnosed prevalence and yearly diagnosed fraction (YDF) in people with low CD4 count. Results: The estimated annual number undiagnosed HIV infections with low CD4 count was on average 6,028 (95% confidence interval (CI): 4,954–8,043) from 2012–2014. In 2014, most of the undiagnosed people with low CD4 count were men (82.8%), a third acquired HIV through sex between men (MSM) (35.0%), and heterosexual transmission (33.4%), respectively. The prevalence of undiagnosed HIV infection was 11.3 (95% CI: 9.3–14.9) per 100,000 residents ranging from 0.7 to 20.8 between Italian regions. Nationally the prevalence rate was 280.4 (95% CI: 173.3–450.2) per 100,000 MSM, 8.3 (95% CI: 4.9–13.6) per 100,000 heterosexual men, and 3.0 (95% CI: 1.4–5.6) per 100,000 women. The YDF was highest among heterosexual women (27.1%; 95% CI: 16.9–45.2%). Conclusions: These findings highlight the importance of improving efforts to identify undiagnosed HIV infections primarily among men, both MSM and heterosexual men. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/29667577; info:eu-repo/semantics/altIdentifier/wos/WOS:000429792300004; volume:23; firstpage:23; lastpage:34; numberofpages:12; journal:EUROSURVEILLANCE; http://hdl.handle.net/11567/917835Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85045995786 |
| DOI: | 10.2807/1560-7917.ES.2018.23.15.17-00240 |
| الإتاحة: | https://doi.org/10.2807/1560-7917.ES.2018.23.15.17-00240Test http://hdl.handle.net/11567/917835Test |
| رقم الانضمام: | edsbas.AA17C590 |
| قاعدة البيانات: | BASE |
| DOI: | 10.2807/1560-7917.ES.2018.23.15.17-00240 |
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