Trends in carbapenemase-producing Enterobacteriaceae, France, 2012 to 2014
| العنوان: | Trends in carbapenemase-producing Enterobacteriaceae, France, 2012 to 2014 |
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| المؤلفون: | Valérie Ponties, Gaelle Cuzon, Patrice Nordmann, Laurent Dortet |
| المصدر: | Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, vol. 22, no. 6, pp. 0 Eurosurveillance |
| بيانات النشر: | European Centre for Disease Control and Prevention (ECDC), 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | 0301 basic medicine, Carbapenemase-Producing Enterobacteriaceae, Epidemiology, 030106 microbiology, NDM, Microbial Sensitivity Tests, Biology, Surveillance and Outbreak Report, Polymerase Chain Reaction, beta-Lactam Resistance, beta-Lactamases, K. pneumoniae, Microbiology, 03 medical and health sciences, Antibiotic resistance, Bacterial Proteins, Enterobacteriaceae, Virology, multidrug resistance, France, polycyclic compounds, Humans, OXA-48, OXA-181, Enterobacteriaceae Infections, Public Health, Environmental and Occupational Health, K pneumoniae, Sequence Analysis, DNA, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, Anti-Bacterial Agents, KPC, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics, Bacterial Proteins/isolation & purification, Bacterial Proteins/secretion, Carbapenems/pharmacology, Enterobacteriaceae/enzymology, Enterobacteriaceae/genetics, Enterobacteriaceae/isolation & purification, Enterobacteriaceae Infections/drug therapy, Enterobacteriaceae Infections/epidemiology, Enterobacteriaceae Infections/microbiology, France/epidemiology, beta-Lactamases/genetics, beta-Lactamases/isolation & purification, beta-Lactamases/secretion, Carbapenems, bacteria, France |
| الوصف: | In 2014, a total of 2,976 Enterobacteriaceae isolates with decreased susceptibility to carbapenems were received at the French Associated National Reference Center for Antibiotic Resistance (NRC) and were characterised for their molecular resistance mechanism to carbapenems and compared with results obtained during 2012 and 2013.The overall number of enterobacterial isolates with decreased susceptibility to carbapenems received at the NRC rapidly increased (more than twofold in two years) with a growing proportion of carbapenemase producers (23.1% in 2012 vs 28.6% in 2013 vs 36.2% in 2014). Between 2012 and 2014, the main carbapenemase type was OXA-48, with an increase in OXA-48 variants (mostly OXA-181) and NDM producers, whereas the number KPC producers decreased. We identified a potential spread of OXA-181 producers in the tropical region of Africa. Finally, OXA-48 and OXA-48-related enzymes remained the predominant carbapenemases in France. The number of carbapenemase-producing Escherischia coli isolates was multiplied by fivefold between 2012 and 2014, suggesting a possible dissemination in the community. |
| وصف الملف: | application/pdf |
| تدمد: | 1560-7917 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01aabd3b812863ab5359e29be137d91Test https://doi.org/10.2807/1560-7917.es.2017.22.6.30461Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b01aabd3b812863ab5359e29be137d91 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15607917 |
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