Vegan Diet and Bone Health—Results from the Cross-Sectional RBVD Study
| العنوان: | Vegan Diet and Bone Health—Results from the Cross-Sectional RBVD Study |
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| المؤلفون: | Matthias B. Schulze, Juliane Menzel, Klaus Abraham, Cornelia Weikert, Isabelle Herter-Aeberli, Tanja Schwerdtle, Rima Obeid, Per Magne Ueland, Gabriele I. Stangl |
| المصدر: | Nutrients Volume 13 Issue 2 Nutrients, Vol 13, Iss 685, p 685 (2021) Nutrients, 13 (2) |
| بيانات النشر: | ETH Zurich, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, 0301 basic medicine, vegan, RRR, Body Mass Index, bone health, BUA, SOS, QUS, diet, biomarker, reduced rank regression, chemistry.chemical_compound, 0302 clinical medicine, Bone Density, Ultrasonography, Nutrition and Dietetics, Selenoprotein P, Vegan Diet, Middle Aged, Urinary calcium, Female, lcsh:Nutrition. Foods and food supply, Adult, Vitamin, Diet, Vegan, medicine.medical_specialty, Nutritional Status, chemistry.chemical_element, lcsh:TX341-641, 030209 endocrinology & metabolism, Calcium, Bone health, Article, 03 medical and health sciences, Internal medicine, medicine, Humans, 030109 nutrition & dietetics, business.industry, Glutamine, Calcaneus, Fibroblast Growth Factor-23, Cross-Sectional Studies, Endocrinology, chemistry, business, Biomarkers, Food Science, Hormone |
| الوصف: | Scientific evidence suggests that a vegan diet might be associated with impaired bone health. Therefore, a cross-sectional study (n = 36 vegans, n = 36 omnivores) was used to investigate the associations of veganism with calcaneal quantitative ultrasound (QUS) measurements, along with the investigation of differences in the concentrations of nutrition- and bone-related biomarkers between vegans and omnivores. This study revealed lower levels in the QUS parameters in vegans compared to omnivores, e.g., broadband ultrasound attenuation (vegans: 111.8 ± 10.7 dB/MHz, omnivores: 118.0 ± 10.8 dB/MHz, p = 0.02). Vegans had lower levels of vitamin A, B2, lysine, zinc, selenoprotein P, n-3 fatty acids, urinary iodine, and calcium levels, while the concentrations of vitamin K1, folate, and glutamine were higher in vegans compared to omnivores. Applying a reduced rank regression, 12 out of the 28 biomarkers were identified to contribute most to bone health, i.e., lysine, urinary iodine, thyroid-stimulating hormone, selenoprotein P, vitamin A, leucine, α-klotho, n-3 fatty acids, urinary calcium/magnesium, vitamin B6, and FGF23. All QUS parameters increased across the tertiles of the pattern score. The study provides evidence of lower bone health in vegans compared to omnivores, additionally revealing a combination of nutrition-related biomarkers, which may contribute to bone health. Further studies are needed to confirm these findings. Nutrients, 13 (2) ISSN:2072-6643 |
| وصف الملف: | application/pdf; application/application/pdf |
| اللغة: | English |
| تدمد: | 2072-6643 |
| DOI: | 10.3929/ethz-b-000472648 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d278662d236e115636a68e65235f6fTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b5d278662d236e115636a68e65235f6f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20726643 |
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| DOI: | 10.3929/ethz-b-000472648 |