The role of environmental factors in insulin-dependent diabetes mellitus: an unresolved issue
| العنوان: | The role of environmental factors in insulin-dependent diabetes mellitus: an unresolved issue |
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| المؤلفون: | Roland Tisch, Meredith R. Kraine |
| المصدر: | Environmental Health Perspectives |
| بيانات النشر: | Environmental Health Perspectives, 1999. |
| سنة النشر: | 1999 |
| مصطلحات موضوعية: | endocrine system diseases, T-Lymphocytes, Health, Toxicology and Mutagenesis, Disease, Biology, Lymphocyte Activation, medicine.disease_cause, Islets of Langerhans, Diabetes mellitus, Unresolved Issue, medicine, Animals, Humans, Autoimmune disease, Superantigens, Incidence (epidemiology), Molecular Mimicry, Public Health, Environmental and Occupational Health, nutritional and metabolic diseases, Bacterial Infections, Environmental Exposure, Environmental exposure, medicine.disease, Diet, Disease Models, Animal, Molecular mimicry, Diabetes Mellitus, Type 1, Virus Diseases, Insulin dependent diabetes, Immunology, Environmental Health, Research Article |
| الوصف: | Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease characterized by the destruction of the insulin-secreting beta cells found in the islets of Langerhans. Reduced beta-cell mass results in overt diabetes, requiring lifelong exogenous insulin administration and the possibility of numerous sequelae. Incidence and development of IDDM depend upon a variety of genetic and nongenetic factors. Environmental factors such as chemicals, diet, and infection are suspected to influence the development of disease. This review describes the work performed to date to elucidate the role of these environmental factors in IDDM. |
| تدمد: | 1552-9924 0091-6765 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670b3db24eedeb68d742181a8933a71dTest https://doi.org/10.1289/ehp.99107s5777Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....670b3db24eedeb68d742181a8933a71d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15529924 00916765 |
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