Small percentage of anaphylactic reactions treated with epinephrine during food challenges in Dutch children
| العنوان: | Small percentage of anaphylactic reactions treated with epinephrine during food challenges in Dutch children |
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| المؤلفون: | Nicolette Arends, Irene Berends, Hans de Groot, Johanna P. M. van der Valk, Harry J. Wichers, Anthony E.J. Dubois, Maurits S. van Maaren, Roy Gerth van Wijk, Nicolette W. de Jong, Joyce A. M. Emons |
| المساهمون: | Groningen Research Institute for Asthma and COPD (GRIAC), Internal Medicine, Pediatrics |
| المصدر: | Annals of allergy asthma & immunology, 120(3), 300-303. ELSEVIER SCIENCE INC Annals of Allergy, Asthma and Immunology 120 (2018) 3 Annals of Allergy, Asthma and Immunology, 120(3), 300-303 Annals of Allergy Asthma & Immunology, 120(3), 300-303. American College of Allergy, Asthma and Immunology |
| بيانات النشر: | ELSEVIER SCIENCE INC, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, Allergy, Arachis, Eggs, medicine.disease_cause, GUIDELINES, DOUBLE-BLIND, 0302 clinical medicine, Allergen, Immunology and Allergy, Respiratory system, Child, Diagnostic Techniques and Procedures, Netherlands, CLINICAL IMMUNOLOGY, Bronchodilator Agents, Health & Consumer Research, Milk, Epinephrine, Child, Preschool, Anesthesia, Female, Food Hypersensitivity, Anaphylaxis, medicine.drug, Pulmonary and Respiratory Medicine, medicine.medical_specialty, EUROPEAN ACADEMY, Adolescent, Immunology, DIAGNOSIS, 03 medical and health sciences, Corylus, Food allergy, 030225 pediatrics, Internal medicine, medicine, Animals, Humans, Life Science, Anacardium, VLAG, Food, Health & Consumer Research, Asthma, business.industry, Infant, Guideline, Allergens, medicine.disease, 030228 respiratory system, Food, ALLERGIC REACTIONS, business, Chickens |
| الوصف: | Background: Severe allergic reactions, including anaphylaxis, occur during oral food challenges (OFCs) and the first-line treatment of anaphylaxis is epinephrine.Objective: To evaluate the percentage of anaphylactic reactions treated with epinephrine during OFCs and to identify associated factors for the administration of epinephrine.Methods: Children who underwent an OFC with peanut, hazelnut, cow's milk, hen's egg, or cashew nut from 2005 through 2015 in the Netherlands were evaluated. Children with reactions meeting the criteria for anaphylaxis according to the European Academy of Allergy and Clinical Immunology guidelines for food allergy and anaphylaxis were included. Children with an anaphylactic reaction treated with vs without epinephrine were compared. Possible factors associated with the administration of epinephrine, such as age, sex, symptoms consistent with asthma, history of an allergic reaction to the tested allergen, and symptom types during the anaphylactic reaction, were evaluated using logistic regression analysis.Results: Eighty-three children in clinical and research settings (43% boys; median age, 7 years; range, 1-17) who met the criteria for anaphylaxis were included in this study. Thirty-two of 83 children (39%) with anaphylaxis were treated with epinephrine. Respiratory symptoms during the OFC were treated significantly more often with epinephrine than gastrointestinal symptoms (P = .01).Conclusion: Only 39% of children with anaphylaxis, according to the guideline criteria, were treated with epinephrine during the OFC and most of these children had respiratory symptoms. There is need for an easy-to-use international guideline for the treatment of allergic symptoms during OFCs. (C) 2017 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved. |
| وصف الملف: | application/pdf; application/octet-stream |
| اللغة: | English |
| تدمد: | 1081-1206 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a1406067fe06f12adb6dcc831ed656Test https://research.rug.nl/en/publications/4d283e6a-4fcf-4ee5-bfcf-275236a90c1aTest |
| حقوق: | RESTRICTED |
| رقم الانضمام: | edsair.doi.dedup.....23a1406067fe06f12adb6dcc831ed656 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10811206 |
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