دورية أكاديمية
Clinical features and comorbidity pattern of HCV infected migrants compared to native patients in care in Italy: A real-life evaluation of the PITER cohort
| العنوان: | Clinical features and comorbidity pattern of HCV infected migrants compared to native patients in care in Italy: A real-life evaluation of the PITER cohort |
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| المؤلفون: | Quaranta, Maria Giovanna, Ferrigno, Luigina, Tata, Xhimi, D'Angelo, Franca, Massari, Marco, Coppola, Carmine, Biliotti, Elisa, Giorgini, Alessia, Laccabue, Diletta, Ciancio, Alessia, Blanc, Pier Luigi, Margotti, Marzia, Ieluzzi, Donatella, Brunetto, Maurizia Rossana, Barbaro, Francesco, Russo, Francesco Paolo, Beretta, Ilaria, Morsica, Giulia, Verucchi, Gabriella, Saracino, Annalisa, Galli, Massimo, Kondili, Loeta A, Cesare Mazzaro, Manuela Bertola, Ornella Schioppa, Antonio Benedetti, Laura Schiadà, Monica Cucco, Andrea Giacometti, Laura Brescini, Sefora Castelletti, Alessandro Fiorentini, Gioacchino Angarano, Michele Milella, Alfredo Di Leo, Maria Rendina, Fulvio Salvatore D'abramo, Chiara Lillo, Andrea Iannone, Mariano Piazzolla, Gabriella Verucchi, Lorenzo Badia, Fabio Piscaglia, Francesca Benevento, Ilaria Serio, Francesco Castelli, Serena Zaltron, Angiola Spinetti, Silvia Odolini, Raffaele Bruno, Mario Mondelli, Luchino Chessa, Martina Loi, Carlo Torti, Chiara Costa, Maria Mazzitelli, Vincenzo Pisani, Vincenzo Scaglione, Enrico Maria Trecarichi, Anna Linda Zignego, Monica Monti, Francesco Madia, Pier Luigi Blanc, Letizia Attala, Piera Pierotti, Elena Salomoni, Elisa Mariabelli, Teresa Antonia Santantonio, Serena Rita Bruno, Ester Marina Cela, Matteo Bassetti, Giovanni Mazzarello, Anna Ida Alessandrini, Antonio Di Biagio, Laura Ambra Nicolini, Giovanni Raimondo, Roberto Filomia, Alessio Aghemo, Rossella Meli, Adriano Lazzarin, Giulia Morsica, Stefania Salpietro, Massimo Galli, Anna Ludovica Fracanzani, Erika Fatta, Rosa Lombardi, Pietro Lampertico, Marta Borghi, Roberta D'ambrosio, Elisabetta Degasperi, Massimo Puoti, Chiara Baiguera, Federico D'amico, Maria Vinci, Maria Grazia Rumi, Massimo Zuin, Alessia Giorgini, Paola Zermiani, Pietro Andreone, Paolo Caraceni, Marzia Margotti, Valeria Guarneri, Erica Villa, Veronica Bernabucci, Laura Bristot, Maria Luisa Paradiso, Guglielmo Migliorino, Ilaria Beretta, Alessandra Gambaro, Giuseppe Lapadula, Anna Spolti, Alessandro Soria, Pietro Invernizzi, Antonio Ciaccio, Martina LucÀ, Federica Malinverno, Laura Ratti, Carmine Coppola, Daniela Caterina Amoruso, Federica Pisano, Ferdinando Scarano, Laura Staiano, Filomena Morisco, Valentina Cossiga, Ivan Gentile, Antonio Riccardo Buonomo, Maria Foggia, Emanuela Zappulo, Alessandro Federico, Marcello Dallio, Nicola Coppola, Caterina Sagnelli, Salvatore Martini, Caterina Monari, Gerardo Nardone, Costantino Sgamato, Liliana Chemello, Luisa Cavalletto, Daniela Sterrantino, Francesco Paolo Russo, Alberto Zanetto, Paola Zanaga, Francesco Barbaro, Giuseppina Brancaccio, Antonio Craxì, Salvatore Petta, Vincenza Calvaruso, Luciano Crapanzano, Salvatore Madonia, Marco Cannizzaro, Erica Maria Bruno, Anna Licata, Simona Amodeo, Adele Rosaria Capitano, Carlo Ferrari, Diletta Laccabue, Elisa Negri, Alessandra Orlandini, Marco Pesci, Roberto Gulminetti, Layla Pagnucco, Giustino Parruti, Paola Di Stefano, Maurizia Rossana Brunetto, Barbara Coco, Marco Massari, Romina Corsini, Elisa Garlassi, Massimo Andreoni, Elisabetta Teti, Carlotta Cerva, Lorenzo Baiocchi, Xhimi Tata, Giuseppe Grassi, Antonio Gasbarrini, Maurizio Pompili, Martina De Siena, Gloria Taliani, Elisa Biliotti, Martina Spaziante, Marcello Persico, Mario Masarone, Andrea Aglitti, Gemma Calvanese, Marco Anselmo, Pasqualina De Leo, Monica Marturano, Giorgio Maria Saracco, Alessia Ciancio, Donatella Ieluzzi |
| المساهمون: | Maria Giovanna, Quaranta, Luigina, Ferrigno, Xhimi, Tata, Franca, D'Angelo, Marco, Massari, Carmine, Coppola, Elisa, Biliotti, Alessia, Giorgini, Diletta, Laccabue, Alessia, Ciancio, Pier Luigi, Blanc, Marzia, Margotti, Donatella, Ieluzzi, Maurizia Rossana, Brunetto, Francesco, Barbaro, Francesco Paolo, Russo, Ilaria, Beretta, Giulia, Morsica, Gabriella, Verucchi, Annalisa, Saracino, Massimo, Galli, Loeta A, Kondili, Mazzaro, Cesare, Bertola, Manuela, Schioppa, Ornella, Benedetti, Antonio, Schiadà, Laura, Cucco, Monica, Giacometti, Andrea, Brescini, Laura, Castelletti, Sefora, Fiorentini, Alessandro, Angarano, Gioacchino, Milella, Michele, Di Leo, Alfredo, Rendina, Maria, Salvatore D'abramo, Fulvio, Lillo, Chiara, Iannone, Andrea, Piazzolla, Mariano, Verucchi, Gabriella, Badia, Lorenzo, Piscaglia, Fabio, Benevento, Francesca, Serio, Ilaria, Castelli, Francesco, Zaltron, Serena, Spinetti, Angiola, Odolini, Silvia, Bruno, Raffaele, Mondelli, Mario, Chessa, Luchino, Loi, Martina, Torti, Carlo, Costa, Chiara, Mazzitelli, Maria, Pisani, Vincenzo, Scaglione, Vincenzo, Maria Trecarichi, Enrico, Linda Zignego, Anna, Monti, Monica, Madia, Francesco, Luigi Blanc, Pier, Attala, Letizia, Pierotti, Piera, Salomoni, Elena, Mariabelli, Elisa, Antonia Santantonio, Teresa, Rita Bruno, Serena, Marina Cela, Ester, Bassetti, Matteo, Mazzarello, Giovanni, Ida Alessandrini, Anna, Di Biagio, Antonio, Ambra Nicolini, Laura, Raimondo, Giovanni, Filomia, Roberto, Aghemo, Alessio, Meli, Rossella, Lazzarin, Adriano, Morsica, Giulia, Salpietro, Stefania, Galli, Massimo, Ludovica Fracanzani, Anna, Fatta, Erika, Lombardi, Rosa, Lampertico, Pietro, Borghi, Marta, D'Ambrosio, Roberta, Degasperi, Elisabetta, Puoti, Massimo, Baiguera, Chiara, D'Amico, Federico, Vinci, Maria, Grazia Rumi, Maria, Zuin, Massimo, Giorgini, Alessia, Zermiani, Paola, Andreone, Pietro, Caraceni, Paolo |
| بيانات النشر: | ELSEVIER SCIENCE INC |
| سنة النشر: | 2021 |
| المجموعة: | Università degli Studi di Messina: IRIS |
| مصطلحات موضوعية: | Comorbiditie, Direct acting antiviral, HCV Cohort, Linked-to-care patient, Aged, Antiviral Agent, Coinfection, Comorbidity, Female, Hepaciviru, Hepatitis C, Chronic, Human, Italy, Male, Middle Aged, Transients and Migrants |
| الوصف: | Background: Direct-acting antivirals are highly effective for the treatment of hepatitis C virus (HCV) infection, regardless race/ethnicity. We aimed to evaluate demographic, virological and clinical data of HCVinfected migrants vs. natives consecutively enrolled in the PITER cohort. Methods: Migrants were defined by country of birth and nationality that was different from Italy. Mann Whitney U test, Chi-squared test and multiple logistic regression were used. Results: Of 10,669 enrolled patients, 301 (2.8%) were migrants: median age 47 vs. 62 years, ( p < 0.001), females 56.5% vs. 45.3%, ( p < 0.001), HBsAg positivity 3.8% vs. 1.4%, ( p < 0.05). Genotype 1b was prevalent in both groups, whereas genotype 4 was more prevalent in migrants ( p < 0.05). Liver disease severity and sustained virologic response (SVR) were similar. A higher prevalence of comorbidities was reported for natives compared to migrants ( p < 0.05). Liver disease progression cofactors (HBsAg, HIV coinfection, alcohol abuse, potential metabolic syndrome) were present in 39.1% and 47.1% ( p > 0.05) of migrants and natives who eradicated HCV, respectively. Conclusion: Compared to natives, HCV-infected migrants in care have different demographics, HCV geno-types, viral coinfections and comorbidities and similar disease severity, SVR and cofactors for disease progression after HCV eradication. A periodic clinical assessment after HCV eradication in Italians and migrants with cofactors for disease progression is warranted. (c) 2021 The Authors. Published by Elsevier Ltd on behalf of Editrice Gastroenterologica Italiana S.r.l. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0Test/) |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/33893040; info:eu-repo/semantics/altIdentifier/wos/WOS:000723376100012; volume:53; issue:12; firstpage:1603; lastpage:1609; numberofpages:7; journal:DIGESTIVE AND LIVER DISEASE; http://hdl.handle.net/11570/3242117Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85104643713 |
| DOI: | 10.1016/j.dld.2021.03.020 |
| الإتاحة: | https://doi.org/10.1016/j.dld.2021.03.020Test http://hdl.handle.net/11570/3242117Test |
| رقم الانضمام: | edsbas.964350E |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.dld.2021.03.020 |
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