دورية أكاديمية

Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017

التفاصيل البيبلوغرافية
العنوان: Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017
المؤلفون: Gillessen, Silke, Attard, Gerhardt, Beer, Tomasz M., Beltran, Himisha, Bossi, Alberto, Bristow, Rob, Carver, Brett, Castellano, Daniel, Chung, Byung Ha, Clarke, Noel, Daugaard, Gedske, Davis, Ian D., de Bono, Johann, dos Reis, Rodolfo Borges, Drake, Charles G., Eeles, Ros, Efstathiou, Eleni, Evans, Christopher P., Fanti, Stefano, Feng, Felix, Fizazi, Karim, Frydenberg, Mark, Gleave, Martin, Halabi, Susan, Heidenreich, Axel, Higano, Celestia S., James, Nicolas, Kantoff, Philip, Kellokumpu-Lehtinen, Pirkko-Liisa, Khauli, Raja B., Kramer, Gero, Logothetis, Chris, Maluf, Fernando, Morgans, Alicia K., Morris, Michael J., Mottet, Nicolas, Murthy, Vedang, Oh, William, Ost, Piet, Padhani, Anwar R., Parker, Chris, Pritchard, Colin C., Roach, Mack, Rubin, Mark A., Ryan, Charles, Saad, Fred, Sartor, Oliver, Scher, Howard, Sella, Avishay, Shore, Neal, Smith, Matthew, Soule, Howard, Sternberg, Cora N., Suzuki, Hiroyoshi, Sweeney, Christopher, Sydes, Matthew R., Tannock, Ian, Tombal, Bertrand, Valdagni, Riccardo, Wiegel, Thomas, Omlin, Aurelius
بيانات النشر: ELSEVIER SCIENCE BV
سنة النشر: 2018
المجموعة: Cologne University: KUPS
مصطلحات موضوعية: ddc:no
الوصف: Backgr(o)und: In advanced prostate cancer (APC), successful drug development as well as advances in imaging and molecular characterisation have resulted in multiple areas where there is lack of evidence or low level of evidence. The Advanced Prostate Cancer Consensus Conference (APCCC) 2017 addressed some of these topics. Objective: To present the report of APCCC 2017. Design, setting, and participants: Ten important areas of controversy in APC management were identified: high-risk localised and locally advanced prostate cancer; oligometastatic'' prostate cancer; castration-naive and castration-resistant prostate cancer; the role of imaging in APC; osteoclast-targeted therapy; molecular characterisation of blood and tissue; genetic counselling/testing; side effects of systemic treatment(s); global access to prostate cancer drugs. A panel of 60 international prostate cancer experts developed the program and the consensus questions. Outcome measurements and statistical analysis: The panel voted publicly but anonymously on 150 predefined questions, which have been developed following a modified Delphi process. Results and limitations: Voting is based on panellist opinion, and thus is not based on a standard literature review or meta-analysis. The outcomes of the voting had varying degrees of support, as reflected in the wording of this article, as well as in the detailed voting results recorded in Supplementary data. Conclusions: The presented expert voting results can be used for support in areas of management of men with APC where there is no high-level evidence, but individualised treatment decisions should as always be based on all of the data available, including disease extent and location, prior therapies regardless of type, host factors including comorbidities, as well as patient preferences, current and emerging evidence, and logistical and economic constraints. Inclusion of men with APC in clinical trials should be strongly encouraged. Importantly, APCCC 2017 again identified important areas in need of ...
نوع الوثيقة: article in journal/newspaper
اللغة: English
العلاقة: Gillessen, Silke orcid:0000-0001-5746-6555 , Attard, Gerhardt, Beer, Tomasz M., Beltran, Himisha, Bossi, Alberto, Bristow, Rob, Carver, Brett, Castellano, Daniel, Chung, Byung Ha, Clarke, Noel, Daugaard, Gedske orcid:0000-0002-9618-9180 , Davis, Ian D., de Bono, Johann, dos Reis, Rodolfo Borges, Drake, Charles G., Eeles, Ros, Efstathiou, Eleni, Evans, Christopher P., Fanti, Stefano, Feng, Felix, Fizazi, Karim, Frydenberg, Mark, Gleave, Martin orcid:0000-0003-4235-0167 , Halabi, Susan orcid:0000-0003-4135-2777 , Heidenreich, Axel, Higano, Celestia S., James, Nicolas, Kantoff, Philip orcid:0000-0001-7275-0597 , Kellokumpu-Lehtinen, Pirkko-Liisa, Khauli, Raja B., Kramer, Gero, Logothetis, Chris, Maluf, Fernando, Morgans, Alicia K., Morris, Michael J. orcid:0000-0002-9454-0096 , Mottet, Nicolas, Murthy, Vedang, Oh, William orcid:0000-0001-5113-8147 , Ost, Piet, Padhani, Anwar R., Parker, Chris, Pritchard, Colin C., Roach, Mack, Rubin, Mark A., Ryan, Charles, Saad, Fred, Sartor, Oliver, Scher, Howard, Sella, Avishay, Shore, Neal, Smith, Matthew, Soule, Howard, Sternberg, Cora N., Suzuki, Hiroyoshi, Sweeney, Christopher, Sydes, Matthew R., Tannock, Ian, Tombal, Bertrand, Valdagni, Riccardo orcid:0000-0001-5140-9728 , Wiegel, Thomas and Omlin, Aurelius (2018). Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017. Eur. Urol., 73 (2). S. 178 - 212. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1873-7560
الإتاحة: https://kups.ub.uni-koeln.de/19645Test/
رقم الانضمام: edsbas.4FD14366
قاعدة البيانات: BASE