Aortic stenosis and cardiac amyloidosis : JACC review topic of the week
| العنوان: | Aortic stenosis and cardiac amyloidosis : JACC review topic of the week |
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| المؤلفون: | Magne, Julien, Krapf, Laura, Mohty, Dania, Côté, Nancy, Pibarot, Philippe, Nguyen, Annabelle, Clavel, Marie-Annick, Galat, Arnault, Ternacle, Julien, Gallet, Romain, Teiger, Emmanuel, Tournoux, François, Damy, Thibaud |
| بيانات النشر: | Elsevier Science |
| سنة النشر: | 2020 |
| المجموعة: | Université Laval: CorpusUL |
| مصطلحات موضوعية: | Aortic stenosis, Cardiac amyloidosis, Doppler echocardiography, Heart failure, Surgical aortic valve replacement, Tafamidis, Transcatheter aortic valve replacement, Transthyretin, Aorte -- Rétrécissement, Amylose (Pathologie), Cœur -- Maladies |
| الوصف: | The prevalence of calcific aortic stenosis (AS) and of cardiac amyloidosis (CA) increases with age, and their association is not uncommon in the elderly. The identification of CA is particularly challenging in patients with AS because these 2 conditions share several features. It is estimated that #15% of the AS population and #30% of the subset with low-flow, low-gradient pattern may have CA. In patients with AS, CA is associated with increased risk of heart failure, mortality, and treatment futility with aortic valve replacement. In case of suspicion of CA, it is thus crucial to confirm the diagnosis to guide therapeutic management of AS and eventually implement recently developed pharmacological treatment dedicated to transthyretin amyloidosis. Given the high surgical risk of patients with AS and concomitant CA, transcatheter aortic valve replacement may be preferred to surgery in these patients. |
| نوع الوثيقة: | other/unknown material |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0735-1097 |
| العلاقة: | http://hdl.handle.net/20.500.11794/39588Test |
| DOI: | 10.1016/j.jacc.2019.09.056 |
| الإتاحة: | https://doi.org/20.500.11794/39588Test https://doi.org/10.1016/j.jacc.2019.09.056Test https://hdl.handle.net/20.500.11794/39588Test |
| حقوق: | http://purl.org/coar/access_right/c_16ecTest |
| رقم الانضمام: | edsbas.C889BA56 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 07351097 |
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| DOI: | 10.1016/j.jacc.2019.09.056 |