دورية أكاديمية
Persistence of long-term {COVID}-19 sequelae in patients with cancer: An analysis from the {OnCovid} registry
| العنوان: | Persistence of long-term {COVID}-19 sequelae in patients with cancer: An analysis from the {OnCovid} registry |
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| المؤلفون: | Alessio Cortellini, Ramon Salazar, Alessandra Gennari, Juan Aguilar-Company, Mark Bower, Alexia Bertuzzi, Joan Brunet, Matteo Lambertini, Clara Maluquer, Paolo Pedrazzoli, Alvin JX. Lee, MCarmen Carmona-Garc('(i))a, Thomas Newsom-Davis, Mieke Van Hemelrijck, Andrea Plaja, Alberto Zambelli, Carlo Tondini, Daniele Generali, Rossella Bertulli, Nikolaos Diamantis, Uma Mukherjee, Gianpiero Rizzo, Tamara Yu, Federica Zoratto, Riccardo Bruna, Anna Sureda, Clara Martinez-Vila, Luca Cantini, Francesca Mazzoni, Federica Grosso, Alessandro Parisi, Maristella Saponara, Aleix Prat, David J. Pinato |
| المساهمون: | Cortellini, Alessio, Salazar, Ramon, Gennari, Alessandra, Aguilar-Company, Juan, Bower, Mark, Bertuzzi, Alexia, Brunet, Joan, Lambertini, Matteo, Maluquer, Clara, Pedrazzoli, Paolo, Lee, Alvin JX., Carmona-Garc('(i))a, Mcarmen, Newsom-Davis, Thoma, Van Hemelrijck, Mieke, Plaja, Andrea, Zambelli, Alberto, Tondini, Carlo, Generali, Daniele, Bertulli, Rossella, Diamantis, Nikolao, Mukherjee, Uma, Rizzo, Gianpiero, Yu, Tamara, Zoratto, Federica, Bruna, Riccardo, Sureda, Anna, Martinez-Vila, Clara, Cantini, Luca, Mazzoni, Francesca, Grosso, Federica, Parisi, Alessandro, Saponara, Maristella, Prat, Aleix, Pinato, David J. |
| بيانات النشر: | ELSEVIER SCI LTD THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND |
| سنة النشر: | 2022 |
| المجموعة: | Università degli Studi di Genova: CINECA IRIS |
| مصطلحات موضوعية: | COVID-19, Long-term, Outcome, SARS-CoV-2, Sequelae |
| الوصف: | Introduction: A significant proportion of patients with cancer who recover from Coronavirus Disease 2019 (COVID-19) may experience COVID-19 sequelae in the early post-infection phase, which negatively affect their continuity of care and oncological outcome. The long-term prevalence and clinical impact of the post-COVID-19 syndrome in patients with cancer are largely unknown. Methods: In this study, we describe the time course of COVID-19 sequelae in patients with non-advanced cancers enrolled in the OnCovid registry. Results: Overall, 186 patients were included, with a median observation period of 9.9 months (95%CI:8,8-11.3) post-COVID-19 resolution. After a median interval of 2.3 months post-COVID-19 (interquartile range: 1.4-3.7), 31 patients (16.6%) reported >1 sequelae, including respiratory complications (14, 7.6%), fatigue (13, 7.1%), neuro-cognitive sequelae (7, 3.8%). The vast majority of the patients were not vaccinated prior to COVID-19. COVID-19-related sequelae persisted in 9.8% and 8% of patients 6 and 12 months after COVID-19 reso-lution. Persistence of sequelae at first oncological follow-up was associated with history of complicated COVID-19 (45.2% vs 24.8%, p Z 0.0223), irrespective of oncological features at COVID-19 diagnosis. Conclusion: This study confirms for the first time that, in a largely unvaccinated population, post-COVID-19 syndrome can affect a significant proportion of patients with non-advanced cancer who recovered from the acute illness. COVID-19 sequelae may persist up to 12 months in some patients, highlighting the need for dedicated prevention and supportive strategies. 2022 Elsevier Ltd. All rights reserved. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | STAMPA |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/35576848; info:eu-repo/semantics/altIdentifier/wos/WOS:000808141900002; volume:170; firstpage:10; lastpage:16; numberofpages:7; journal:EUROPEAN JOURNAL OF CANCER; https://hdl.handle.net/11567/1107199Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85130393555 |
| DOI: | 10.1016/j.ejca.2022.03.019 |
| الإتاحة: | https://doi.org/10.1016/j.ejca.2022.03.019Test https://hdl.handle.net/11567/1107199Test |
| رقم الانضمام: | edsbas.B3FFA47 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.ejca.2022.03.019 |
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