التفاصيل البيبلوغرافية
| العنوان: |
Systematic review of loperamide : No proof of antibiotics being superior to loperamide in treatment of mild/moderate travellers' diarrhoea |
| المؤلفون: |
Laaveri, Tinja, Sterne, Jesper, Rombo, Lars, Kantele, Anu |
| المساهمون: |
Department of Medicine, Clinicum, Infektiosairauksien yksikkö, Anu Kantele-Häkkinen Research Group |
| بيانات النشر: |
ELSEVIER SCI IRELAND LTD |
| سنة النشر: |
2016 |
| المجموعة: |
Helsingfors Universitet: HELDA – Helsingin yliopiston digitaalinen arkisto |
| مصطلحات موضوعية: |
Adverse drug event, Safety, Antibiotics, Antidiarrhoeals, Antibiotic resistance, IRRITABLE-BOWEL-SYNDROME, LACTAMASE-PRODUCING ENTEROBACTERIACEAE, CLOSTRIDIUM-DIFFICILE INFECTION, RESOURCE-LIMITED DESTINATIONS, US MILITARY PERSONNEL, TOXIC MEGACOLON, ANTIMICROBIAL RESISTANCE, ACUTE-PANCREATITIS, PLUS LOPERAMIDE, RISK-FACTORS, 3142 Public health care science, environmental and occupational health |
| الوصف: |
Looking at the worldwide emergency of antimicrobial resistance, international travellers appear to have a central role in spreading the bacteria across the globe. Travellers' diarrhoea (TD) is the most common disease encountered by visitors to the (sub) tropics. Both TD and its treatment with antibiotics have proved significant independent risk factors of colonization by resistant intestinal bacteria while travelling. Travellers should therefore be given preventive advice regarding TD and cautioned about taking antibiotics: mild or moderate TD does not require antibiotics. Logical alternatives are medications with effects on gastrointestinal function, such as loperamide. The present review explores literature on loperamide in treating TD. Adhering to manufacturer's dosage recommendations, loperamide offers a safe and effective alternative for relieving mild and moderate symptoms. Moreover, loperamide taken singly does no predispose to contracting MDR bacteria. Most importantly, we found no proof that would show antibiotics to be significantly more effective than loperamide in treating mild/moderate TD. (C) 2016 The Authors. Published by Elsevier Ltd. ; Peer reviewed |
| نوع الوثيقة: |
review |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Laaveri , T , Sterne , J , Rombo , L & Kantele , A 2016 , ' Systematic review of loperamide : No proof of antibiotics being superior to loperamide in treatment of mild/moderate travellers' diarrhoea ' , Travel medicine and infectious disease , vol. 14 , no. 4 , pp. 299-312 . https://doi.org/10.1016/j.tmaid.2016.06.006Test; 84992663659; 918b620f-e3cf-4cf3-84e2-77d9c8c1cdd2; http://hdl.handle.net/10138/167666Test; 000382235000003 |
| الإتاحة: |
http://hdl.handle.net/10138/167666Test |
| حقوق: |
cc_by_nc_nd ; openAccess ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.897CD10 |
| قاعدة البيانات: |
BASE |
