المؤلفون: Kazuhiro Ohara, Edward R. Kastenhuber, Piro Lito, Michael Saborowski, Takaaki Miura, Christof Fellmann, Nobuya Ishii, Eric W. Joseph, Neal Rosen, Christine Lukacs, Jingyin Yue, Martha Solomon, Scott W. Lowe, Kenji Morikami, Anna Saborowski, Sunyana Gadal

المصدر: Cancer Cell. (5):697-710

مصطلحات موضوعية: Cancer Research, Indoles, endocrine system diseases, Mutant, MAP Kinase Kinase 1, medicine.disease_cause, Mice, Coumarins, Phosphorylation, RNA, Small Interfering, Vemurafenib, Extracellular Signal-Regulated MAP Kinases, Melanoma, Gene knockdown, Sulfonamides, Oncology, Benzamides, RNA Interference, raf Kinases, KRAS, medicine.drug, Proto-Oncogene Proteins B-raf, MAP Kinase Signaling System, Pyridones, Mice, Nude, Pyrimidinones, Biology, Article, Cell Line, Proto-Oncogene Proteins p21(ras), Proto-Oncogene Proteins, medicine, Animals, Humans, neoplasms, Protein Kinase Inhibitors, Oncogene, TNF Receptor-Associated Factor 3, Diphenylamine, Cell Biology, Surface Plasmon Resonance, medicine.disease, digestive system diseases, HEK293 Cells, Drug Resistance, Neoplasm, Cancer research, ras Proteins, V600E

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c70d2d8328ae21aca4e8bd16c7e2d53Test

المؤلفون: Manjula Santhanakrishnan, Nicholas Theodosakis, Glenn Merlino, David Dankort, Ildiko Erdelyi, David P. Curley, Laura Huang, Goran Micevic, Marcus Bosenberg, Viswanathan Muthusamy, Nabeel Bardeesy, Martin McMahon, William Damsky, Katrina Meeth, Michael A. Davies, M. Raza Zaidi, James T. Platt, Scott Tighe

المصدر: Cancer Cell. (1):41-56

مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, Cancer Research, Skin Neoplasms, Molecular Sequence Data, Melanoma, Experimental, Mechanistic Target of Rapamycin Complex 2, Biology, AMP-Activated Protein Kinases, Mechanistic Target of Rapamycin Complex 1, Protein Serine-Threonine Kinases, mTORC2, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, CDKN2A, Cell Line, Tumor, medicine, Nevus, Animals, Humans, skin and connective tissue diseases, Protein kinase B, neoplasms, PI3K/AKT/mTOR pathway, Cyclin-Dependent Kinase Inhibitor p16, 030304 developmental biology, Cell Proliferation, 0303 health sciences, Melanoma, TOR Serine-Threonine Kinases, Cell Biology, Melanocytic nevus, medicine.disease, digestive system diseases, MicroRNAs, Oncology, 030220 oncology & carcinogenesis, Multiprotein Complexes, Mutation, Cancer research, Melanocytes, V600E, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0044ff3927b36cd5f042454e90436d94Test

المؤلفون: Bonnie E. Gould Rothberg, Manjula Santhanakrishnan, Lara E. Rosenbaum, David Dankort, David L. Rimm, James T. Platt, Marcus Bosenberg, David P. Curley, Makoto Mark Taketo, William Damsky, Martin McMahon

المصدر: Cancer Cell. (6):741-754

مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, Lung Neoplasms, Skin Neoplasms, Transcription, Genetic, Melanoma, Experimental, Kaplan-Meier Estimate, Piperazines, Metastasis, Mice, 0302 clinical medicine, Tumor Cells, Cultured, Phosphorylation, beta Catenin, 0303 health sciences, Protein Stability, Melanoma, Wnt signaling pathway, Cell Transformation, Neoplastic, Oncology, Gene Knockdown Techniques, Lymphatic Metastasis, 030220 oncology & carcinogenesis, Benzamides, Imatinib Mesylate, Melanocytes, Colorectal Neoplasms, Signal Transduction, Proto-Oncogene Proteins B-raf, Mice, 129 Strain, Mice, Transgenic, Biology, Article, 03 medical and health sciences, medicine, Animals, Humans, PTEN, neoplasms, Protein kinase B, PI3K/AKT/mTOR pathway, 030304 developmental biology, Splenic Neoplasms, PTEN Phosphohydrolase, Cell Biology, medicine.disease, Antigens, Differentiation, Enzyme Activation, Mice, Inbred C57BL, Pyrimidines, Imatinib mesylate, Cancer research, biology.protein, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be8670ebdea02852cfac85a39f570a4Test

المؤلفون: Felix Dietlein, Martin R. Sprick, Bastian Kalb, Daniel Rauh, Jirina Bartkova, Elisa M. Noll, Lars Tharun, Allan Bradley, Alessandro Torgovnick, Cornelia Mauch, Reinhard Büttner, Helen Künstlinger, Andreas Trumpp, Winfried Randerath, Kato Kambartel, Roman K. Thomas, Roland Rad, Florian Siedek, André Richters, Anna Schmitt, Jürgen Wolf, Mladen Jokic, Alexander Strong, H. Christian Reinhardt, Thorsten Persigehl, Luka Ozretić, Dieter Saur, Jiri Bartek, Christian Jüngst

المصدر: Cell

مصطلحات موضوعية: Lung Neoplasms, Cell cycle checkpoint, endocrine system diseases, Mutant, Medizin, Apoptosis, Bioinformatics, medicine.disease_cause, Mice, 0302 clinical medicine, Tumor Cells, Cultured, Enzyme Inhibitors, Mitotic catastrophe, 0303 health sciences, Intracellular Signaling Peptides and Proteins, Drug Synergism, 3. Good health, synergism, Chk-1, MK2, Kras, cancer, 030220 oncology & carcinogenesis, Heterografts, Adenocarcinoma, KRAS, Proto-Oncogene Proteins B-raf, DNA damage, Adenocarcinoma of Lung, Antineoplastic Agents, Protein Serine-Threonine Kinases, Biology, General Biochemistry, Genetics and Molecular Biology, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Proto-Oncogene Proteins, medicine, Animals, Humans, CHEK1, neoplasms, 030304 developmental biology, Biochemistry, Genetics and Molecular Biology(all), Cell Cycle Checkpoints, medicine.disease, digestive system diseases, Disease Models, Animal, enzymes and coenzymes (carbohydrates), Checkpoint Kinase 1, Cancer cell, ras Proteins, Cancer research, Protein Kinases, Neoplasm Transplantation, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e292ad27ffc043d2860ae26b51664674Test