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1

SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment

المصدر: Cell Metabolism
Cell metabolism, vol 33, iss 8

مصطلحات موضوعية: 0301 basic medicine, Male, Physiology, type 1 diabetes, Cell, ACE2, Apoptosis, Medical Biochemistry and Metabolomics, neuropilin 1, 0302 clinical medicine, Insulin-Secreting Cells, Receptors, 80 and over, Insulin, 2.1 Biological and endogenous factors, Aetiology, Receptor, Lung, Serine Endopeptidases, Diabetes, Transferrin, apoptosis, phosphoproteomics, Middle Aged, Spike Glycoprotein, Virus, CD, SARS-CoV-2 spike protein, Cell killing, medicine.anatomical_structure, Infectious Diseases, Host-Pathogen Interactions, Pneumonia & Influenza, Female, Angiotensin-Converting Enzyme 2, Adult, Cell signaling, insulin, Biology, Autoimmune Disease, 03 medical and health sciences, Endocrinology & Metabolism, Clinical Research, medicine, Diabetes Mellitus, Humans, Secretion, Antigens, Molecular Biology, Metabolic and endocrine, Aged, A549 cell, Type 1 diabetes, SARS-CoV-2, Prevention, fungi, COVID-19, Cell Biology, Pneumonia, Virus Internalization, Clinical and Translational Report, medicine.disease, Neuropilin-1, Coronavirus, 030104 developmental biology, Emerging Infectious Diseases, Good Health and Well Being, A549 Cells, Case-Control Studies, Cancer research, pancreatic beta cell, Biochemistry and Cell Biology, Apoptosis Regulatory Proteins, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29dfd8b903035a419ccf9d57cbd7e975Test
http://europepmc.org/articles/PMC8130512Test

2

Infiltrating T lymphocytes and programmed cell death protein-1/programmed death-ligand 1 expression in endometriosis-associated ovarian cancer

المؤلفون: Alessia Romito, Alessandra De Cicco Nardone, Ursula Catena, Anna Fagotti, Gianfranco Zannoni, Camilla Nero, Giovanni Scambia, Maria De Ninno, L.C. Turco, Rossana Moroni, Saveria Spadola, Ilaria Romito, Francesco Cosentino

مصطلحات موضوعية: Adult, PD-L1, medicine.medical_specialty, T-Lymphocytes, Programmed Cell Death 1 Receptor, Endometriosis, Carcinoma, Ovarian Epithelial, medicine.disease_cause, Gastroenterology, B7-H1 Antigen, endometriosis-associated ovarian cancer, Cell Movement, Internal medicine, PD-1, medicine, Humans, infiltrating lymphocytes, Retrospective Studies, Ovarian Neoplasms, biology, business.industry, Obstetrics and Gynecology, Cancer, Middle Aged, medicine.disease, Immunohistochemistry, Chemotaxis, Leukocyte, Settore MED/40 - GINECOLOGIA E OSTETRICIA, Reproductive Medicine, Italy, Case-Control Studies, Ovarian Endometriosis, biology.protein, Female, Atypical Endometriosis, Ovarian cancer, business, Carcinogenesis, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98bed499751b8487fb92a060e6805390Test
http://hdl.handle.net/10807/193861Test

3

Phase 2 Trial of Nivolumab Combined With Stereotactic Body Radiation Therapy in Patients With Metastatic or Locally Advanced Inoperable Melanoma

المؤلفون: Annabel Meireson, Piet Ost, Teofila Seremet, Jo Van Dorpe, Liesbeth Ferdinande, Nora Sundahl, Bart Neyns, Lieve Brochez, Vibeke Kruse

المساهمون: Clinical sciences, Medical Oncology, Laboratory for Medical and Molecular Oncology, Laboratory of Molecullar and Cellular Therapy

مصطلحات موضوعية: Oncology, Male, Cancer Research, Radiosurgery/adverse effects, Skin Neoplasms, Melanoma/blood, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Programmed Cell Death 1 Receptor/blood, Pembrolizumab, Kaplan-Meier Estimate, Chemoradiotherapy/adverse effects, 030218 nuclear medicine & medical imaging, GTP Phosphohydrolases, 0302 clinical medicine, Antineoplastic Agents, Immunological, Clinical endpoint, Melanoma, Skin Neoplasms/blood, Medicine(all), Radiation, GTP Phosphohydrolases/blood, Chemoradiotherapy, DNA, Neoplasm, Middle Aged, Progression-Free Survival, Nivolumab, Response Evaluation Criteria in Solid Tumors, 030220 oncology & carcinogenesis, Female, medicine.drug, Proto-Oncogene Proteins B-raf, Adult, Antineoplastic Agents, Immunological/adverse effects, medicine.medical_specialty, DNA, Neoplasm/blood, Ipilimumab, Radiosurgery, Drug Administration Schedule, 03 medical and health sciences, Internal medicine, medicine, Biomarkers, Tumor, Humans, Radiology, Nuclear Medicine and imaging, Progression-free survival, Aged, Proto-Oncogene Proteins B-raf/blood, business.industry, Membrane Proteins/blood, Membrane Proteins, medicine.disease, Nivolumab/adverse effects, Radiation therapy, Biomarkers, Tumor/blood, business, Progressive disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f6019cfc276207deb92a753bddb0b2Test
https://biblio.vub.ac.be/vubir/phase-2-trial-of-nivolumab-combined-with-stereotactic-body-radiation-therapy-in-patients-with-metastatic-or-locally-advanced-inoperable-melanomaTest(707a28c4-923a-46bd-96f3-69c0fb0f2a41).html

4

A decade-long telemedicine screening program for diabetic retinopathy in the north-east of Italy

المؤلفون: Edoardo Midena, Porzia Pucci, Stela Vujosevic, Fabiano Cavarzeran, Margherita Casciano, Angelo Avogaro, Annarita Daniele, Silvia Bini, Marianna Berton, Annunziata Lapolla

مصطلحات موضوعية: Male, Diabetic maculopathy, Diabetic retinopathy screening, Epidemiology, Sight threatening diabetic retinopathy, Telemedicine, Internal Medicine, Endocrinology, Diabetes and Metabolism, Endocrinology, Cohort Studies, 0302 clinical medicine, Risk Factors, Prevalence, Mass Screening, Longitudinal Studies, Aged, 80 and over, Incidence (epidemiology), Incidence, Diabetic retinopathy, Middle Aged, Diabetes and Metabolism, Italy, Disease Progression, Female, Cohort study, Adult, medicine.medical_specialty, Adolescent, 030209 endocrinology & metabolism, Sensitivity and Specificity, 03 medical and health sciences, Young Adult, Diabetes mellitus, Ophthalmology, Internal medicine, medicine, Humans, Risk factor, Aged, Diabetic Retinopathy, business.industry, Type 2 Diabetes Mellitus, medicine.disease, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, 030221 ophthalmology & optometry, Maculopathy, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d651592ca59da713923d4971180b0aTest
http://hdl.handle.net/11577/3240219Test

5

GPR119 expression in normal human tissues and islet cell tumors: evidence for its islet-gastrointestinal distribution, expression in pancreatic beta and alpha cells, and involvement in islet function

المؤلفون: Ken Ebihara, Kyoichi Takaori, Shinji Odori, Junji Fujikura, Ryuichiro Doi, Yoshiharu Sakai, Yoshiya Kawaguchi, Shinji Uemoto, Kiminori Hosoda, Tsutomu Tomita, Kazuwa Nakao, Toru Kusakabe

المصدر: Metabolism: clinical and experimental. 62(1):70-78

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, endocrine system, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Glucagonoma, Biology, Receptors, G-Protein-Coupled, Mice, Young Adult, Endocrinology, Free fatty acid receptor 1, Internal medicine, Insulin-Secreting Cells, Gene expression, medicine, Animals, Humans, RNA, Messenger, Gastrointestinal hormones, Insulinoma, Aged, geography, geography.geographical_feature_category, Reverse Transcriptase Polymerase Chain Reaction, Pancreatic islets, Insulin secretion, Middle Aged, Islet, medicine.disease, Gastrointestinal Tract, Gene Expression Regulation, Neoplastic, Mice, Inbred C57BL, Pancreatic Neoplasms, medicine.anatomical_structure, Glucagon-Secreting Cells, Duodenum, Regression Analysis, Female, Pancreas

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e1e50872c91fa16aa0fcb1e2e65483Test
http://hdl.handle.net/2433/171382Test

6

Wilms Tumor 1 Expression and Pre-emptive Immunotherapy in Patients with Acute Myeloid Leukemia Undergoing an Allogeneic Hemopoietic Stem Cell Transplantation

مصطلحات موضوعية: Male, Oncology, Premedication, medicine.medical_treatment, Hematopoietic stem cell transplantation, urologic and male genital diseases, Immunotherapy, Adoptive, Wilms tumor 1 (WT1), 0302 clinical medicine, hemic and lymphatic diseases, Allogeneic hemopoietic stem cell transplantation, Cumulative incidence, Hematopoietic Stem Cell Transplantation, Myeloid leukemia, Hematology, Middle Aged, female genital diseases and pregnancy complications, Leukemia, Myeloid, Acute, Lymphocyte Transfusion, 030220 oncology & carcinogenesis, Female, Immunotherapy, Adult, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Adolescent, Bone Marrow Cells, Donor lymphocyte infusion, Young Adult, 03 medical and health sciences, Internal medicine, medicine, Humans, Transplantation, Homologous, WT1 Proteins, Aged, Transplantation, Acute myeloid leukemia, urogenital system, business.industry, Wilms' tumor, medicine.disease, Minimal residual disease, Settore MED/15 - MALATTIE DEL SANGUE, Immunology, business, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daef28452e7ad76e1d76dd8e3f2bd143Test
http://hdl.handle.net/11567/873430Test

7

Long-term human coronavirus-myelin cross-reactive T-cell clones derived from multiple sclerosis patients

المؤلفون: Pierre Duquette, Pierre J. Talbot, Annie Boucher, Marc Desforges

المصدر: Clinical Immunology (Orlando, Fla.)

مصطلحات موضوعية: Male, Proteolipid protein 1, Time Factors, Receptors, Antigen, T-Cell, alpha-beta, T-Lymphocytes, Autoimmunity, T-Cell Antigen Receptor Specificity, medicine.disease_cause, Lymphocyte Activation, Myelin, Epitopes, 0302 clinical medicine, Immunology and Allergy, Coronaviridae, Antigens, Viral, Myelin Sheath, Coronavirus, 0303 health sciences, biology, Reverse Transcriptase Polymerase Chain Reaction, virus diseases, Middle Aged, Multiple Sclerosis, Chronic Progressive, 3. Good health, Molecular mimicry, medicine.anatomical_structure, Female, Human, Adult, Multiple Sclerosis, Immunology, T lymphocytes, Antigen-Presenting Cells, Article, 03 medical and health sciences, Multiple Sclerosis, Relapsing-Remitting, medicine, Humans, Amino Acid Sequence, Myelin Proteolipid Protein, 030304 developmental biology, Aged, Cell Proliferation, Multiple sclerosis, Myelin Basic Protein, biology.organism_classification, medicine.disease, Virology, Myelin basic protein, Clone Cells, biology.protein, Viral neuroimmunology, T cell receptor, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53618b284dd8abd6fc6437360f815dc3Test
http://europepmc.org/articles/PMC7106099Test

8

IFIH1 gene polymorphisms in type 1 diabetes

المؤلفون: Jan Van Autreve, Ilse Weets, Bart Van Der Auwera, Folefac Aminkeng, Frans Gorus, Chris Van Schravendijk, Erik Quartier

المساهمون: Medical Biochemistry, Pathologic Biochemistry and Physiology, Clinical Biology, Beta Cell Neogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e745a973e74621cd1af52b893cdc22c7Test
https://hdl.handle.net/20.500.14017/39787f42-7ea9-409b-8fa0-04398be1f455Test

9

Integrated molecular analysis suggests a three-class model for low-grade gliomas: A proof-of-concept study

المؤلفون: Nicholas F. Marko, Richard A. Prayson, Gene H. Barnett, Robert J. Weil

المصدر: Genomics. (1):16-24

مصطلحات موضوعية: Adult, Male, Mixed Glioma, Adolescent, Population, Genomics, Computational biology, Biology, Microarray, Bioinformatics, Central Nervous System Neoplasms, Glioma, Genetics, medicine, Humans, Child, education, Grading (tumors), neoplasms, Oligonucleotide Array Sequence Analysis, Electronic Data Processing, education.field_of_study, Genome, Human, Gene Expression Profiling, Class model, Low grade, Middle Aged, medicine.disease, Classification, Immunohistochemistry, Molecular analysis, nervous system diseases, Gene Expression Regulation, Neoplastic, Gene expression profiling, Chromosomes, Human, Pair 1, RNA, Female, Gene expression, Chromosome Deletion, Chromosomes, Human, Pair 19, Algorithms

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74eb32cded536a29f17cca8609ad8598Test

10

Role of adiponectin in human skeletal muscle bioenergetics

المؤلفون: Matthew W. Hulver, Anthony E. Civitarese, Lawrence J. Mandarino, Stacy Carling, Steve R. Smith, Eric Ravussin, Barbara Ukropcova, Ralph A. DeFronzo

المصدر: Cell Metabolism. (1):75-87

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Physiology, HUMDISEASE, Receptors, Cell Surface, Mitochondrion, DNA, Mitochondrial, Article, Mice, Insulin resistance, Internal medicine, medicine, Animals, Humans, Myocyte, Citrate synthase, Muscle, Skeletal, Molecular Biology, Cells, Cultured, Mice, Knockout, Adiponectin receptor 1, Muscle Cells, Adiponectin, biology, Skeletal muscle, Cell Biology, medicine.disease, Mitochondria, Mice, Inbred C57BL, medicine.anatomical_structure, Endocrinology, Diabetes Mellitus, Type 2, Mitochondrial biogenesis, SIGNALING, biology.protein, Female, Insulin Resistance, Receptors, Adiponectin, Energy Metabolism, Reactive Oxygen Species, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7100afafd5805f36923a53b03b7f70e5Test

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