دورية أكاديمية
Xenograft rejection: IgG1, complement and NK cells team up to activate and destroy the endothelium
العنوان: | Xenograft rejection: IgG1, complement and NK cells team up to activate and destroy the endothelium |
---|---|
المؤلفون: | Rieben, Robert, Seebach, Jörg D |
المصدر: | Rieben, Robert; Seebach, Jörg D (2005). Xenograft rejection: IgG1, complement and NK cells team up to activate and destroy the endothelium. Trends in immunology, 26(1), pp. 2-5. Oxford: Elsevier Current Trends 10.1016/j.it.2004.11.011 |
بيانات النشر: | Elsevier Current Trends |
سنة النشر: | 2005 |
المجموعة: | BORIS (Bern Open Repository and Information System, University of Bern) |
الوصف: | Acute vascular rejection represents a formidable barrier to clinical xenotransplantation and it is known that this type of rejection can also be initiated by xenoreactive antibodies that have limited complement-activating ability. Using a sophisticated mouse model, a recent study has provided in vivo evidence for the existence of an IgG(1)-mediated vascular rejection, which uniquely depends on both the activation of complement and interactions with FcgammaRIII on natural killer (NK) cells. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
العلاقة: | https://boris.unibe.ch/31677Test/ |
الإتاحة: | https://doi.org/10.1016/j.it.2004.11.011Test https://boris.unibe.ch/31677Test/ |
حقوق: | info:eu-repo/semantics/restrictedAccess |
رقم الانضمام: | edsbas.76AFA745 |
قاعدة البيانات: | BASE |
الوصف غير متاح. |