نتائج البحث - "PRR, Pattern-Recognition Receptor"

1

Lifestyle-mediated nitric oxide boost to prevent SARS-CoV-2 infection: A perspective

المؤلفون: Jun Kobayashi

المصدر: Nitric Oxide

مصطلحات موضوعية: Cancer Research, ARDS, Physiology, N2O3, dinitrogen trioxide, Clinical Biochemistry, PRR, pattern-recognition receptor, NF-κB, nuclear factor-κB, Physical exercise, Review, Disease, ACE2, angiotensin-converting enzyme 2, medicine.disease_cause, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Biochemistry, 3CL, 3-chymotrypsin-like, Pathogenesis, Immune system, Diabetes mellitus, medicine, Humans, IFN, interferon, 内皮障害, NO+, nitrosonium ion, Endothelial dysfunction, TMPRSS2, transmembrane protease serine 2, Life Style, COVID-19, coronavirus disease, ARDS, acute respiratory distress syndrome, Coronavirus, NO, nitric oxide, SARS-CoV-2, 急性呼吸窮迫症候群, business.industry, COVID-19, eNOS, NO synthase, Nitric oxide, 新型コロナウイルス, Lifestyle, medicine.disease, 生活習慣, Immunology, cGMP, cyclic guanosine-3′,5′-monophosphate, AT1R, Ang-Ⅱ type 1 receptor, 新型コロナウイルス感染症, 一酸化窒素, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97dbc32e2c6c06eab04e000be1c5a1bdTest
https://doi.org/10.1016/j.niox.2021.08.001Test

2

The immune response to SARS-CoV-2 and COVID-19 immunopathology – Current perspectives

المؤلفون: A. Morais, Luís Delgado, Inês Chora, José Laerte Boechat

المصدر: Pulmonology, Vol 27, Iss 5, Pp 423-437 (2021)
Pulmonology

مصطلحات موضوعية: PRR, pattern recognition receptor, Chemokine, ICs, immune complexes, viruses, Review, Adaptive Immunity, medicine.disease_cause, Severity of Illness Index, IRFs, interferon regulatory factors, 0302 clinical medicine, S protein, spike protein, Immunopathology, Medicine, 030212 general & internal medicine, SARS-CoV-2, coronavirus-related second severe acute respiratory syndrome, COVID-19, coronavirus disease 2019, Coronavirus, Innate immunity, Respiratory Distress Syndrome, TNF, tumor necrosis factor, biology, RBD, receptor-binding domain, Middle Aged, Acquired immune system, ICU, intensive care unit, MASP-2, MBL-associated serine protease-2, VEGF, vascular endothelial growth factor, NF-kB, nuclear factor kB, Disease Progression, Immunotherapy, Antibody, Adult, ACE-2, angiotensin-converting enzyme 2, Pulmonary and Respiratory Medicine, ILCs, innate lymphocytes or innate lymphoid cells, Antiviral Agents, Virus, Diseases of the respiratory system, 03 medical and health sciences, Immune system, Humans, IFN, interferon, SARS, severe acute respiratory syndrome, ARDS, acute respiratory distress syndrome, Aged, Inflammation, Innate immune system, RC705-779, SARS-CoV-2, business.industry, COVID-19, biochemical phenomena, metabolism, and nutrition, Respiration, Artificial, Immunity, Innate, IL, interleukin, MAS, macrophage activation syndrome, SARS-CoV-1, coronavirus-related first severe acute respiratory syndrome, IVIG, intravenous immunoglobulin, MERS-CoV, coronavirus-related Middle Eastern Respiratory syndrome, 030228 respiratory system, DAMPs, damage-associated molecular patterns, Immunology, MBL, mannose binding lectin, biology.protein, MoAb, monoclonal antibody, Lung Diseases, Interstitial, C, complement factor (e.g. C3a, C3b, C4, C5, C5a), business, CoV, coronaviruses

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9b7f4bc7b02b1302a387d92564f7baTest
https://doi.org/10.1016/j.pulmoe.2021.03.008Test

3

TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants

المؤلفون: Matija Hedl, Clara Abraham, Rui Sun

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 249-272 (2021)

مصطلحات موضوعية: 0301 basic medicine, FADD, Fas-associated protein with death domain, MDP, muramyl dipeptide, DR3, death receptor 3, Mice, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, Enterococcus faecalis, Cells, Cultured, Original Research, TNF, tumor necrosis factor, IBD, inflammatory bowel disease, TRADD, tumor necrosis factor receptor 1-associated death domain, Gastroenterology, MDM, monocyte-derived macrophages, TACE, tumor necrosis factor converting enzyme, LC3II, light chain 3-II, Autocrine Communication, TNFSF15, TNF superfamily member 15, Receptors, Pattern Recognition, 030211 gastroenterology & hepatology, Tumor necrosis factor alpha, Signal transduction, PI3K, phosphoinositide 3-kinase, Crohn’s Disease, TLR, Toll-like receptor, Signal Transduction, Tumor Necrosis Factor Ligand Superfamily Member 15, MALT1, mucosa-associated lymphoid tissue lymphoma translocation protein 1, Primary Cell Culture, NF-κB, nuclear factor-κB, PRR, pattern-recognition receptor, TRAF2, TNF receptor associated factor 2, Biology, NOD, nucleotide-binding oligomerization domain, RNS, reactive nitrogen species, 03 medical and health sciences, Paracrine signalling, ROS, reactive oxygen species, RIP, receptor-interacting protein kinase, PDK1, pyruvate dehydrogenase kinase 1, Paracrine Communication, Genetics, Escherichia coli, Animals, Humans, Genetic Predisposition to Disease, lcsh:RC799-869, NOS2, nitric oxide synthase 2, Autocrine signalling, Protein kinase A, Receptors, Tumor Necrosis Factor, Member 25, Death domain, Hepatology, NEMO, NF-κB essential modulator, Macrophages, NADPH, nicotinamide adenine dinucleotide phosphate, Inflammatory Bowel Diseases, IL, interleukin, 030104 developmental biology, BMDM, bone marrow–derived macrophage, siRNA, small interfering RNA, Cancer research, lcsh:Diseases of the digestive system. Gastroenterology, JNK, Janus kinase, Cytokine secretion, Pattern Recognition Receptors, Death receptor 3, MAPK, mitogen-activated protein kinase, AIEC, adherent invasive Escherichia coli

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb21b1a8b74b5bc07131da592a5389bdTest
https://doi.org/10.1016/j.jcmgh.2020.08.003Test

4

Deimmunization of protein therapeutics – Recent advances in experimental and computational epitope prediction and deletion

المؤلفون: Martin J. Loessner, Mathias Schmelcher, Noël Stierlin, Léa V. Zinsli

المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 315-329 (2021)
Computational and Structural Biotechnology Journal, 19

مصطلحات موضوعية: HAP, Homo-amino-acid polymer, NMR, Nuclear magnetic resonance, EPO, Erythropoietin, ANN, Artificial neural network, ELP, Elastin-like polypeptide, APC, Antigen-presenting cell, Review, SVM, Support vector machine, Ig, Immunoglobulin, Biochemistry, Epitope, chemistry.chemical_compound, 0302 clinical medicine, Structural Biology, BCR, B cell receptor, IL, Interleukin, PAMP, Pathogen-associated molecular pattern, LPS, Lipopolysaccharide, ADA, Anti-drug antibody, 0303 health sciences, Protein therapeutics, TCR, T cell receptor, Immunogenicity, Protein therapeutic, Anti-drug-antibody, T cell epitope, B cell epitope, GLK, Gelatin-like protein, PBMC, Peripheral blood mononuclear cell, RNN, Recurrent artificial neural network, ABR, Antigen-binding region, DC, Dendritic cell, Computer Science Applications, HLA, Human leukocyte antigen, PD, Pharmacodynamics, TAP, Transporter associated with antigen processing, PEG, Polyethylene glycol, 030220 oncology & carcinogenesis, TLR, Toll-like receptor, Biotechnology, PRR, Pattern recognition receptor, ER, Endoplasmatic reticulum, Glycosylation, Reductive methylation, Biophysics, HMM, Hidden Markov model, Mutagenesis (molecular biology technique), CDR, Complementarity determining region, Computational biology, Biology, PAS, Polypeptide composed of proline, alanine, and/or serine, PSA, Sialic acid polymers, 03 medical and health sciences, CRISPR, Clustered regularly interspaced short palindromic repeats, Genetics, PK, Pharmacokinetics, Deimmunization, ComputingMethodologies_COMPUTERGRAPHICS, 030304 developmental biology, MHC, Major histocompatibility complex, Bab, Binding antibody, XTEN, “Xtended” recombinant polypeptide, Nab, Neutralizing antibody, chemistry, PEGylation, TP248.13-248.65

وصف الملف: application/application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc6eb34d6710e1da9ae4b3df006a799Test
https://doi.org/10.1016/j.csbj.2020.12.024Test

5

IL23 Promotes Antimicrobial Pathways in Human Macrophages, Which Are Reduced With the IBD-Protective IL23R R381Q Variant

المؤلفون: Rui Sun, Clara Abraham

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 4, Pp 673-697 (2020)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, Th, T-helper cell, Interleukin-23, 0302 clinical medicine, MDMs, monocyte-derived macrophages, Macrophage, Cells, Cultured, Original Research, GFP, green fluorescent protein, TNF, tumor necrosis factor, Janus kinase 2, IBD, inflammatory bowel disease, biology, Chemistry, TYK2, Tyrosine kinase 2, Gastroenterology, Nitric oxide synthase 2, PI3K, phosphatidylinositol 3-kinase, Cell biology, LC3II, light chain 3-II, STAT, signal transducer and activator of transcription, Interleukin 12, LPS, lipopolysaccharide, 030211 gastroenterology & hepatology, JAK, Janus kinase, Infection, NK, natural killer, Intracellular, Crohn’s Disease, PRR, pattern-recognition receptor, Cell Line, NOD, nucleotide-binding oligomerization domain, RNS, reactive nitrogen species, 03 medical and health sciences, Paracrine signalling, ROS, reactive oxygen species, Immune system, PDK1, pyruvate dehydrogenase kinase 1, Autophagy, Genetics, Humans, Point Mutation, Ulcerative Colitis, IFN, interferon, lcsh:RC799-869, NOS2, nitric oxide synthase 2, Autocrine signalling, Bacteria, Hepatology, Macrophages, Receptors, Interleukin, NADPH, nicotinamide adenine dinucleotide phosphate, Inflammatory Bowel Diseases, IL, interleukin, 030104 developmental biology, siRNA, small interfering RNA, biology.protein, lcsh:Diseases of the digestive system. Gastroenterology, AIEC, adherent invasive Escherichia coli