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المؤلفون: Mohsen Khosravi-Maharlooei, Rachel Madley, Chiara Borsotti, Leonardo M.R. Ferreira, Robert C. Sharp, Michael A. Brehm, Dale L. Greiner, Audrey V. Parent, Mark S. Anderson, Megan Sykes, Remi J. Creusot
المصدر: Molecular Metabolism
مصطلحات موضوعية: Physiology, Autoimmunity, Review, mTEC, medullary thymic epithelial cell, Mice, DC, dendritic cell, BCR, B cell receptor, Humanized mice, Insulin-Secreting Cells, 2.1 Biological and endogenous factors, Aetiology, PI, personalized immune, Pediatric, xGvHD, xenogeneic graft-versus-host disease, TCR, T cell receptor, Diabetes, T1D, Type 1 diabetes, RBC, red blood cell, In vitro models, SNP, single nucleotide polymorphism, HC, healthy control, MPS, microphysiological system, SP, single positive, Type 1 diabetes, Disease modeling, NOD, non-obese diabetic, NK, natural killer, Type 1, DP, double positive, iPSC, induced pluripotent stem cell, PBMC, peripheral blood mononuclear cell, Beta cell destruction, TOC, thymic organ culture, Treg, regulatory T cell, Autoimmune Disease, Clinical Research, HSC, hematopoietic stem cell, Diabetes Mellitus, Genetics, Animals, Humans, Molecular Biology, Metabolic and endocrine, HLA, human leukocyte antigen, Prevention, Inflammatory and immune system, Cell Biology, MHC, major histocompatibility, hPSC, human pluripotent stem cell, Diabetes Mellitus, Type 1, APC, antigen-presenting cell, Immune System, HIS, human immune system, Biochemistry and Cell Biology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cbcfb9a236a8de465abdfc6194c120Test
https://doi.org/10.1016/j.molmet.2021.101417Test -
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المؤلفون: Dale L. Greiner, Cynthia Greer, Florie Borel, Gwladys Gernoux, Mark A. Kay, Adi Barzel, Ziqiong Wang, Christian Mueller, Michael A. Brehm, Leonard D. Shultz, Terence R. Flotte, Qiushi Tang
المصدر: Molecular Therapy
مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_treatment, Genetic enhancement, Mutant, Gene Expression, Mice, Mice, Inbred NOD, shRNA, Mutant protein, Drug Discovery, Transgenes, liver regeneration, Gene Editing, biology, Graft Survival, AAV, Dependovirus, Liver regeneration, liver xenograft, AAT, 3. Good health, medicine.anatomical_structure, α-1 antitrypsin deficiency, Neutrophil elastase, Hepatocyte, Molecular Medicine, Original Article, A1AT, humanized liver mouse model, congenital, hereditary, and neonatal diseases and abnormalities, Xenotransplantation, Genetic Vectors, Transplantation, Heterologous, 03 medical and health sciences, alpha 1-Antitrypsin Deficiency, Genetics, medicine, Animals, Humans, nuclease-free genome editing, Gene silencing, Gene Silencing, Molecular Biology, miRNA, Pharmacology, AATD, Genetic Therapy, Disease Models, Animal, MicroRNAs, 030104 developmental biology, alpha 1-Antitrypsin, RNAi, Mutation, Immunology, Hepatocytes, Cancer research, biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a88330846ed0be913632d8ecb1a96de9Test
https://doi.org/10.1016/j.ymthe.2017.09.020Test -
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المؤلفون: Julia Clemens, Mohit K Verma, Lisa M. Burzenski, Michael A. Brehm, Stephen Byers Sampson, Dale L. Greiner, Leonard D. Shultz
المصدر: Journal of Immunological Methods. 446:47-53
مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Immunology, Mice, SCID, Monoclonal antibody, Article, Antibodies, Monoclonal, Murine-Derived, Mice, 03 medical and health sciences, Mice, Inbred NOD, In vivo, Cell Line, Tumor, hemic and lymphatic diseases, medicine, Animals, Immunology and Allergy, Cytotoxic T cell, Cytotoxicity, CD20, biology, Antibody-Dependent Cell Cytotoxicity, Antibodies, Monoclonal, Complement System Proteins, Antigens, CD20, Molecular biology, Complement system, Disease Models, Animal, 030104 developmental biology, biology.protein, NSG mouse, Cancer research, Heterografts, Immunotherapy, Rituximab, Complement membrane attack complex
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d1657d6d48df74c1ff251a48101e41Test
https://doi.org/10.1016/j.jim.2017.03.021Test -
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المؤلفون: Roger J. Davis, Myoung Sook Han, Tamera Barrett, Michael A. Brehm
المصدر: Cell Reports, Vol 15, Iss 1, Pp 19-26 (2016)
مصطلحات موضوعية: Male, 0301 basic medicine, Carcinoma, Hepatocellular, Myeloid, MAP Kinase Kinase 4, Inflammation, Article, General Biochemistry, Genetics and Molecular Biology, Hepatitis, Mice, 03 medical and health sciences, Liver disease, 0302 clinical medicine, hemic and lymphatic diseases, medicine, Carcinoma, Animals, Myeloid Cells, lcsh:QH301-705.5, Kinase, business.industry, Liver Neoplasms, medicine.disease, 3. Good health, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, lcsh:Biology (General), 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Immunology, medicine.symptom, Signal transduction, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9151e43c01748703a27ec2bed92dc37Test
https://doi.org/10.1016/j.celrep.2016.03.008Test -
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المؤلفون: Laurie L. Kenney, Dale L. Greiner, Michael A. Brehm, Leonard D. Shultz
المصدر: American Journal of Transplantation. 16:389-397
مصطلحات موضوعية: 0301 basic medicine, Transplantation, medicine.medical_specialty, business.industry, chemical and pharmacologic phenomena, Regenerative medicine, Organ transplantation, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Immune system, Allograft rejection, Immunology, Humanized mouse, Immunology and Allergy, Medicine, Pharmacology (medical), Stem cell, Available drugs, business, 030215 immunology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8c216650e5ef8e0bb3d351a284e5c688Test
https://doi.org/10.1111/ajt.13520Test -
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المؤلفون: Michael A. Brehm, Terence R. Flotte, Shaoyong Li, Mengxin Li, Dale L. Greiner, Li Zhong, Qiushi Tang, Arun Srivastava, Qin Su, Ran He, Chen Ling, Guangping Gao, Leonard D. Shultz, Christian Mueller
المصدر: Molecular Therapy. 23:1867-1876
مصطلحات موضوعية: Liver cytology, Genetic enhancement, Genetic Vectors, Green Fluorescent Proteins, Virus, Green fluorescent protein, Mice, 03 medical and health sciences, Transduction (genetics), 0302 clinical medicine, Transduction, Genetic, Cell Line, Tumor, Drug Discovery, Genetics, Animals, Humans, Molecular Biology, 030304 developmental biology, Pharmacology, 0303 health sciences, biology, Liver Neoplasms, Genetic Therapy, Dependovirus, Macaca mulatta, Molecular biology, 3. Good health, Gene Expression Regulation, Neoplastic, Disease Models, Animal, Liver, Cell culture, RHCG, 030220 oncology & carcinogenesis, Cancer cell, Hepatocytes, biology.protein, Molecular Medicine, Original Article, Capsid Proteins, Neoplasm Transplantation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ba44837839c69a6324299edb731c88Test
https://doi.org/10.1038/mt.2015.174Test -
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المؤلفون: Alexander R. Schmidt, Vinzenz Lange, Geoffrey A. Behrens, Michael A. Brehm, Tatjana Wehde, Gerhard Schöfl, Rita Groß, Jana Heider, Santina Castriciano
المصدر: Human Immunology. 80:130
مصطلحات موضوعية: CMV status, business.industry, Immunology, Buccal swab, Immunology and Allergy, Medicine, General Medicine, Donor registration, business, Throughput (business), Virology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::abff2da726cd474f8269caec641746cbTest
https://doi.org/10.1016/j.humimm.2019.07.158Test -
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المصدر: Virology. :213-217
مصطلحات موضوعية: Male, Cross Protection, viruses, T cell, Epitopes, T-Lymphocyte, Heterologous, chemical and pharmacologic phenomena, CD8-Positive T-Lymphocytes, Cross Reactions, Biology, Immunity, Heterologous, Lymphocytic choriomeningitis, Major histocompatibility complex, Article, Epitope, Virus, Major Histocompatibility Complex, Mice, Epitopes, Heterologous immunity, Immunity, Virology, medicine, Animals, Arenaviridae Infections, Humans, Lymphocytic choriomeningitis virus, Pichinde virus, Pathogen, biochemical phenomena, metabolism, and nutrition, medicine.disease, Arenaviruses, Mice, Inbred C57BL, medicine.anatomical_structure, Cross-reactivity CD8 T cell, Immunology, biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a52c850942a7a8a45b08bfcacb78d67Test
https://doi.org/10.1016/j.virol.2014.07.012Test -
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المؤلفون: Johann Bauersachs, Michael-Ulrich Brehm, Jan-Thorben Sieweke, Mechthild Westhoff-Bleck, Andreas Schäfer, L.C. Napp, Murat Avsar, Jens Vogel-Claussen
المصدر: International Journal of Cardiology. 203:138-140
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Ejection fraction, medicine.diagnostic_test, Heart disease, business.industry, Disease progression, Electrocardiography in myocardial infarction, 030204 cardiovascular system & hematology, medicine.disease, Pericardial effusion, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Heart failure, Internal medicine, medicine, Cardiology, Myocardial infarction, Cardiology and Cardiovascular Medicine, business, Electrocardiography
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::80ad491074e259dacf32a3f818627043Test
https://doi.org/10.1016/j.ijcard.2015.10.020Test -
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المؤلفون: Michael A. Brehm, Dale L. Greiner, Leonard D. Shultz, Nathalie Jouvet
المصدر: Current Opinion in Immunology. 25:428-435
مصطلحات موضوعية: Extramural, Immunology, Human pathogen, Biology, Communicable Diseases, Virology, Article, Translational Research, Biomedical, Pathogenesis, Disease Models, Animal, Mice, In vivo, Small animal, Animals, Humans, Immunology and Allergy
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1697670451402083b33aa67babcc2439Test
https://doi.org/10.1016/j.coi.2013.05.012Test