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المؤلفون: Pratima Chowdary, Margareta Holmström, Johnny N. Mahlangu, Margaret C. Ozelo, Ingrid Pabinger, K. John Pasi, Margaret V. Ragni, Amy Shapiro, Chris Barnowski, Stefan Lethagen
المصدر: Research and Practice in Thrombosis and Haemostasis. 6:e12760
مصطلحات موضوعية: factor IX fc fusion protein, factor VIII Fc fusion protein, hemophilia A, hemophilia B, recombinant fusion proteins, safety, surgical procedures, Pediatrik, Hematology, Pediatrics
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1dbc299e18ee716a32cfbf794b52b0Test
https://doi.org/10.1002/rth2.12760Test -
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المؤلفون: John Pasi, Desmond Creagh, D. J. Perry, Ruth Pink, Gregory M. Hayes, Amanda Clark, Sylvia Fong, Sophia Stanford, Gillian C. Lowe, Savita Rangarajan, Kandiah Chandrakumaran, Nicola Curry
المصدر: Research and Practice in Thrombosis and Haemostasis
مصطلحات موضوعية: Original Articles: Haemostasis, Serotype, seroprevalence, biology, business.industry, Genetic enhancement, adeno‐associated viral vectors, Hematology, Virus, Viral vector, Cohort, Immunology, biology.protein, Seroprevalence, Medicine, Original Article, hemophilia A, Vector (molecular biology), Antibody, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2476659e13f941e87501a741ca0983e5Test
https://doi.org/10.1002/rth2.12177Test -
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المؤلفون: Gavin Arno, Keren J. Carss, Sarah Hull, Ceniz Zihni, Anthony G. Robson, Alessia Fiorentino, Alison J. Hardcastle, Graham E. Holder, Michael E. Cheetham, Vincent Plagnol, Anthony T. Moore, F. Lucy Raymond, Karl Matter, Maria S. Balda, Andrew R. Webster, Graeme Black, Georgina Hall, Stuart Ingram, Rachel Gillespie, Forbes Manson, Panagiotis Sergouniotis, Chris Inglehearn, Carmel Toomes, Manir Ali, Martin McKibbin, James Poulter, Kamron Khan, Emma Lord, Andrea Nemeth, Susan Downes, Stephanie Halford, Jing Yu, Stefano Lise, Nikos Ponitkos, Michel Michaelides, Veronica van Heyningen, Timothy Aitman, Hana Alachkar, Sonia Ali, Louise Allen, David Allsup, Gautum Ambegaonkar, Julie Anderson, Richard Antrobus, Ruth Armstrong, Gururaj Arumugakani, Sofie Ashford, William Astle, Antony Attwood, Steve Austin, Chiara Bacchelli, Tamam Bakchoul, Tadbir K. Bariana, Helen Baxendale, David Bennett, Claire Bethune, Shahnaz Bibi, Maria Bitner-Glindzicz, Marta Bleda, Harm Boggard, Paula Bolton-Maggs, Claire Booth, John R. Bradley, Angie Brady, Matthew Brown, Michael Browning, Christine Bryson, Siobhan Burns, Paul Calleja, Natalie Canham, Jenny Carmichael, Keren Carss, Mark Caulfield, Elizabeth Chalmers, Anita Chandra, Patrick Chinnery, Manali Chitre, Colin Church, Emma Clement, Naomi Clements-Brod, Virginia Clowes, Gerry Coghlan, Peter Collins, Nichola Cooper, Amanda Creaser-Myers, Rosa DaCosta, Louise Daugherty, Sophie Davies, John Davis, Minka De Vries, Patrick Deegan, Sri V.V. Deevi, Charu Deshpande, Lisa Devlin, Eleanor Dewhurst, Rainer Doffinger, Natalie Dormand, Elizabeth Drewe, David Edgar, William Egner, Wendy N. Erber, Marie Erwood, Tamara Everington, Remi Favier, Helen Firth, Debra Fletcher, Frances Flinter, James C. Fox, Amy Frary, Kathleen Freson, Bruce Furie, Abigail Furnell, Daniel Gale, Alice Gardham, Michael Gattens, Neeti Ghali, Pavandeep K. Ghataorhe, Rohit Ghurye, Simon Gibbs, Kimberley Gilmour, Paul Gissen, Sarah Goddard, Keith Gomez, Pavel Gordins, Stefan Gräf, Daniel Greene, Alan Greenhalgh, Andreas Greinacher, Sofia Grigoriadou, Detelina Grozeva, Scott Hackett, Charaka Hadinnapola, Rosie Hague, Matthias Haimel, Csaba Halmagyi, Tracey Hammerton, Daniel Hart, Grant Hayman, Johan W.M. Heemskerk, Robert Henderson, Anke Hensiek, Yvonne Henskens, Archana Herwadkar, Simon Holden, Muriel Holder, Susan Holder, Fengyuan Hu, Aarnoud Huissoon, Marc Humbert, Jane Hurst, Roger James, Stephen Jolles, Dragana Josifova, Rashid Kazmi, David Keeling, Peter Kelleher, Anne M. Kelly, Fiona Kennedy, David Kiely, Nathalie Kingston, Ania Koziell, Deepa Krishnakumar, Taco W. Kuijpers, Dinakantha Kumararatne, Manju Kurian, Michael A. Laffan, Michele P. Lambert, Hana Lango Allen, Allan Lawrie, Sara Lear, Melissa Lees, Claire Lentaigne, Ri Liesner, Rachel Linger, Hilary Longhurst, Lorena Lorenzo, Rajiv Machado, Rob Mackenzie, Robert MacLaren, Eamonn Maher, Jesmeen Maimaris, Sarah Mangles, Ania Manson, Rutendo Mapeta, Hugh S. Markus, Jennifer Martin, Larahmie Masati, Mary Mathias, Vera Matser, Anna Maw, Elizabeth McDermott, Coleen McJannet, Stuart Meacham, Sharon Meehan, Karyn Megy, Sarju Mehta, Carolyn M. Millar, Shahin Moledina, Anthony Moore, Nicholas Morrell, Andrew Mumford, Sai Murng, Elaine Murphy, Sergey Nejentsev, Sadia Noorani, Paquita Nurden, Eric Oksenhendler, Willem H. Ouwehand, Sofia Papadia, Soo-Mi Park, Alasdair Parker, John Pasi, Chris Patch, Joan Paterson, Jeanette Payne, Andrew Peacock, Kathelijne Peerlinck, Christopher J. Penkett, Joanna Pepke-Zaba, David J. Perry, Val Pollock, Gary Polwarth, Mark Ponsford, Waseem Qasim, Isabella Quinti, Stuart Rankin, Julia Rankin, Karola Rehnstrom, Evan Reid, Christopher J. Rhodes, Michael Richards, Sylvia Richardson, Alex Richter, Irene Roberts, Matthew Rondina, Elisabeth Rosser, Catherine Roughley, Kevin Rue-Albrecht, Crina Samarghitean, Alba Sanchis-Juan, Richard Sandford, Saikat Santra, Ravishankar Sargur, Sinisa Savic, Sol Schulman, Harald Schulze, Richard Scott, Marie Scully, Suranjith Seneviratne, Carrock Sewell, Olga Shamardina, Debbie Shipley, Ilenia Simeoni, Suthesh Sivapalaratnam, Kenneth Smith, Aman Sohal, Laura Southgate, Simon Staines, Emily Staples, Hans Stauss, Penelope Stein, Jonathan Stephens, Kathleen Stirrups, Sophie Stock, Jay Suntharalingam, R. Campbell Tait, Kate Talks, Yvonne Tan, Jecko Thachil, James Thaventhiran, Ellen Thomas, Moira Thomas, Dorothy Thompson, Adrian Thrasher, Marc Tischkowitz, Catherine Titterton, Cheng-Hock Toh, Mark Toshner, Carmen Treacy, Richard Trembath, Salih Tuna, Wojciech Turek, Ernest Turro, Chris Van Geet, Marijke Veltman, Julie Vogt, Julie von Ziegenweldt, Anton Vonk Noordegraaf, Emma Wakeling, Ivy Wanjiku, Timothy Q. Warner, Evangeline Wassmer, Hugh Watkins, Andrew Webster, Steve Welch, Sarah Westbury, John Wharton, Deborah Whitehorn, Martin Wilkins, Lisa Willcocks, Catherine Williamson, Geoffrey Woods, John Wort, Nigel Yeatman, Patrick Yong, Tim Young, Ping Yu
المساهمون: Pediatric surgery, Molecular cell biology and Immunology, Pulmonary medicine, ACS - Pulmonary hypertension & thrombosis, APH - Quality of Care, Amsterdam Reproduction & Development (AR&D), RS: CARIM - R1.04 - Clinical thrombosis and haemostasis, MUMC+: DA CDL Algemeen (9), Med Microbiol, Infect Dis & Infect Prev
المصدر: UK Inherited Retinal Disease Consortium, NIHR BioResource Rare Diseases Consortium, NIHR BioResource Rare Diseases Consortium & NIHR Bioresource – Rare Diseases Consortium 2017, ' Biallelic Mutation of ARHGEF18, Involved in the Determination of Epithelial Apicobasal Polarity, Causes Adult-Onset Retinal Degeneration ', American journal of human genetics, vol. 100, no. 2, pp. 334-342 . https://doi.org/10.1016/j.ajhg.2016.12.014Test
American journal of human genetics, vol 100, iss 2
American journal of human genetics, 100(2), 334-342. Cell Press
American Journal of Human Genetics, 100(2), 334-342. Cell Pressمصطلحات موضوعية: Male, 0301 basic medicine, Retinal degeneration, Biallelic Mutation, RHOA, PROTEIN, Eye, Medical and Health Sciences, ACTIVATION, chemistry.chemical_compound, 0302 clinical medicine, 2.1 Biological and endogenous factors, Missense mutation, Exome, Aetiology, Genetics (clinical), Genetics & Heredity, Genetics, biology, Retinal Degeneration, Cell Polarity, MOSAIC EYES, Biological Sciences, Middle Aged, Phenotype, inherited retinal dystrophy, Pedigree, UK Inherited Retinal Disease Consortium, Female, apicobasal polarity, Retinal Dystrophies, Adult, NIHR Bioresource - Rare Diseases Consortium, ARHGEF18, Genotype, Mutation, Missense, Nerve Tissue Proteins, Retina, 03 medical and health sciences, Rare Diseases, retinitis pigmentosa, Report, CRB1, Retinitis pigmentosa, medicine, Humans, Amino Acid Sequence, Eye Proteins, Eye Disease and Disorders of Vision, Alleles, Human Genome, Neurosciences, Genetic Variation, Membrane Proteins, Epithelial Cells, Retinal, CELL FEATURES, medicine.disease, NUCLEOTIDE EXCHANGE FACTOR, p114RhoGEF, 030104 developmental biology, INTEGRATIVE GENOMICS VIEWER, OKO-MEDUZY, chemistry, Mutation, MORPHOGENESIS, 030221 ophthalmology & optometry, biology.protein, Missense, rhoA GTP-Binding Protein, Rho Guanine Nucleotide Exchange Factors, Genome-Wide Association Study
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4831e3f022992cabfb6e762b39655afTest
https://doi.org/10.1016/j.ajhg.2016.12.014Test -
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المؤلفون: Glenn F. Pierce, Guy Young, Johnny Mahlangu, Lynda M. Cristiano, Chris Barnes, Roshni Kulkarni, Beatrice Nolan, John Pasi, G. Allen, Srividya Neelakantan, Giulia Gambino, R. Liesner
المصدر: Journal of Thrombosis and Haemostasis. 13:967-977
مصطلحات موضوعية: Male, China, Pediatrics, medicine.medical_specialty, Recombinant Fusion Proteins, Population, Hemophilia A, Severity of Illness Index, Drug Administration Schedule, South Africa, Pharmacokinetics, Risk Factors, Internal medicine, Hemarthrosis, Severity of illness, Clinical endpoint, Humans, Medicine, Child, Infusions, Intravenous, education, Adverse effect, education.field_of_study, Factor VIII, Coagulants, business.industry, Age Factors, Australia, Hematology, Bleed, medicine.disease, Antibodies, Neutralizing, Immunoglobulin Fc Fragments, Europe, Regimen, Treatment Outcome, Child, Preschool, North America, Female, business, Half-Life
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6426bd1f0ecc2973f52f4530a7c57fTest
https://doi.org/10.1111/jth.12911Test -
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المؤلفون: Paul J. Murdock, Henry K. Bayele, K. John Pasi
المصدر: Biochimica et Biophysica Acta (BBA) - General Subjects. 1800:398-404
مصطلحات موضوعية: Blood Platelets, Protein Folding, Isomerase activity, Coenzymes, Biophysics, Biochemistry, Catalysis, Factor IXa, Tissue factor, chemistry.chemical_compound, Thioredoxins, Prothrombinase, Humans, Disulfides, Platelet activation, Blood Coagulation, Molecular Biology, Factor VIII, Chemistry, Factor X, Glutathione, Recombinant Proteins, Coagulation, Factor Xa, Oxidoreductases, Oxidation-Reduction, Tenase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16d95c4281ac923e29677a73753dba9Test
https://doi.org/10.1016/j.bbagen.2009.12.006Test -
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المؤلفون: Jenny Goudemand, Ian R. Peake, John Pasi, Augusto B. Federici, Javier Batlle, Frank Hill, U. Budde, Claudine Mazurier, Jeroen Eikenboom, Reinhard Schneppenheim, David Habart, Anne Goodeve, K. Bertoncello, Zdena Vorlova, Dominique Meyer, F. Rodeghiero, Jørgen Ingerslev, Giancarlo Castaman, M. Bernardi, Stefan Lethagen, Alberto Tosetto, Lars Holmberg
المصدر: Journal of Thrombosis and Haemostasis. 5:715-721
مصطلحات موضوعية: Adult, Male, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Adolescent, Ristocetin cofactor activity, Gastroenterology, Cohort Studies, Sex Factors, Von Willebrand factor, hemic and lymphatic diseases, ABO blood group system, Internal medicine, von Willebrand Factor, Von Willebrand disease, Humans, Medicine, Child, Aged, Aged, 80 and over, biology, business.industry, Age Factors, Infant, Hematology, Middle Aged, medicine.disease, Europe, von Willebrand Diseases, Child, Preschool, Immunology, cardiovascular system, biology.protein, Female, business, circulatory and respiratory physiology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84b3e61b16f787db212f2a257a09724Test
https://doi.org/10.1111/j.1538-7836.2007.02444.xTest -
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المؤلفون: David S. Rampton, K. John Pasi, Peter M. Irving
المصدر: Clinical Gastroenterology and Hepatology. 3:617-628
مصطلحات موضوعية: Crohn's disease, Hepatology, business.industry, digestive, oral, and skin physiology, Gastroenterology, Thrombosis, Inflammation, Disease, Inflammatory Bowel Diseases, Platelet Activation, medicine.disease, Inflammatory bowel disease, Ulcerative colitis, digestive system diseases, Proinflammatory cytokine, Pathogenesis, Immunology, medicine, Humans, medicine.symptom, business, Blood Coagulation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d97f6f2e4a5e8b6d089528d192c5651Test
https://doi.org/10.1016/s1542-3565Test(05)00154-0 -
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المؤلفون: Henry K. Bayele, Martin O'donell, Alexander T. Florence, Christine Lee, Istvan Toth, Andrew F. Wilderspin, K. John Pasi, Thiagarajan Sakthivel
المصدر: Journal of Pharmaceutical Sciences. 94:446-457
مصطلحات موضوعية: Pharmaceutical Science, Peptide, CHO Cells, Biology, Gene delivery, Transfection, Jurkat Cells, Cricetulus, Cell Line, Tumor, Cricetinae, Nucleic Acids, Dendrimer, Chlorocebus aethiops, Animals, Humans, Luciferase, Luciferases, chemistry.chemical_classification, Drug Carriers, Oligonucleotide, RNA, Amino acid, chemistry, Biochemistry, COS Cells, Liposomes, Nucleic acid, RNA Interference, Peptides, HeLa Cells
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9cb9edeb8b5f0a41620f022147d229Test
https://doi.org/10.1002/jps.20230Test -
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المؤلفون: Christina A. Oppenheimer, Karen Dampier, Paramjeet S. Deol, Sue R. Pavord, K. John Pasi, Christopher C. Watson, Fiona Miall, Tim A. Barnes
المصدر: Thrombosis Research. 115:461-467
مصطلحات موضوعية: Adult, medicine.medical_specialty, Time Factors, Whole Blood Coagulation Time, Complications of pregnancy, Adolescent, Pregnancy Trimester, Third, Comorbidity, Thrombophilia, Predictive Value of Tests, Pregnancy, Risk Factors, Factor V Leiden, medicine, Humans, Prospective Studies, Prothrombin time, medicine.diagnostic_test, business.industry, Obstetrics, Antithrombin, Hematology, medicine.disease, United Kingdom, Thrombelastography, Surgery, Pregnancy Complications, Female, Blood Coagulation Tests, business, circulatory and respiratory physiology, medicine.drug, Partial thromboplastin time
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299e7e109e7832036c1f327ef3830e62Test
https://doi.org/10.1016/j.thromres.2004.09.019Test -
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المؤلفون: K. John Pasi, Paula H. B. Bolton-Maggs
المصدر: The Lancet. 361:1801-1809
مصطلحات موضوعية: Male, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Haemophilia A, Disease, Hemophilia A, Infections, Haemophilia, Hemophilia B, hemic and lymphatic diseases, medicine, Coagulopathy, Humans, Haemophilia B, Intensive care medicine, Factor IX, Factor VIII, business.industry, Transfusion Reaction, Genetic Therapy, General Medicine, medicine.disease, Pedigree, Surgery, Coagulation, Factor X, Mutation, Life expectancy, Female, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19e28876ed2d7174dedb809a7a3319aTest
https://doi.org/10.1016/s0140-6736Test(03)13405-8