المؤلفون: Drouin-Ouellet, Janelle, Legault, Emilie M, Nilsson, Fredrik, Pircs, Karolina, Bouquety, Julie, Petit, Florence, Shrigley, Shelby, Birtele, Marcella, Pereira, Maria, Storm, Petter, Sharma, Yogita, Bruzelius, Andreas, Vuono, Romina, Kele, Malin, Stoker, Thomas B, Ottosson, Daniella Rylander, Falk, Anna, Jakobsson, Johan, Barker, Roger A, Parmar, Malin

المصدر: essn: 2213-6711 ; nlmid: 101611300

مصطلحات موضوعية: Parkinson's disease, alpha-synuclein, autophagy, direct neural reprogramming, dopaminergic neurons, induced neurons, induced pluripotent stem cells, Adult, Humans, Parkinson Disease

وصف الملف: application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/342455Test

الإتاحة: https://doi.org/10.17863/CAM.89875Test
https://www.repository.cam.ac.uk/handle/1810/342455Test

المؤلفون: Amy J. Hulme, Simon Maksour, Mitchell St-Clair Glover, Sara Miellet, Mirella Dottori

المصدر: Stem Cell Reports

مصطلحات موضوعية: Pluripotent Stem Cells, neural differentiation, Neurogenesis, Cell Culture Techniques, Cell- and Tissue-Based Therapy, neural progenitors, Nerve Tissue Proteins, Review, Biochemistry, NGN2, Neural Stem Cells, Basic Helix-Loop-Helix Transcription Factors, Genetics, Animals, Humans, Cell Lineage, Neurogenin-2, transcription factor, Neurons, Cell Differentiation, Cell Biology, High-Throughput Screening Assays, induced neurons, nervous system, Gene Expression Regulation, Biomarkers, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6bf7d67c04d8714593365188d750920Test
https://doi.org/10.1016/j.stemcr.2021.11.015Test

المؤلفون: Shauna H. Yuan, Johannes C. M. Schlachetzki, Fred H. Gage, Dylan A. Reid, Apuã C. M. Paquola, Raffaella Lucciola, Shani Stern, Attila Szücs, Larissa Traxler, Steve Horvath, Lena Böhnke, Douglas Galasko, Simon T. Schafer, Frank Edenhofer, Christopher K. Glass, Dina Zangwill, Lukas Karbacher, Jerome Mertens, Diana P. Fernandes, Lucia Zhou-Yang, Lawrence S.B. Goldstein, Manching Ku, Hyungjun Lee, Joseph R. Herdy, Ravi K. Agarwal

المصدر: Cell Stem Cell

مصطلحات موضوعية: Aging, Ontogeny, Induced Pluripotent Stem Cells, rejuvenation, neuronal cell cycle re-entry, Age dependent, Biology, induced neurons (iNs), Article, Malignant transformation, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Alzheimer Disease, Genetics, Humans, Epigenetics, Aged, 030304 developmental biology, Neurons, 0303 health sciences, de-differentiation, Cell Biology, Alzheimer's disease, Fibroblasts, Cell cycle, nervous system, Molecular Medicine, Signal transduction, Neuroscience, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee680604bac20b52230ab834cd93afcTest
https://doi.org/10.1016/j.stem.2021.04.004Test

المؤلفون: Sonia Levi, Valeria Tiranti, Sabrina Dusi, Michela Guaraldo, Barbara Garavaglia, Vania Broccoli, Paolo Santambrogio, Luisa Ida Rotundo

المساهمون: Santambrogio, Paolo, Dusi, Sabrina, Guaraldo, Michela, Rotundo, Luisa Ida, Broccoli, Vania, Garavaglia, Barbara, Tiranti, VALERIA SONIA, Levi, Sonia, Santambrogio, P, Dusi, S, Guaraldo, M, Rotundo, Li, Broccoli, V, Garavaglia, B, Tiranti, V, Levi, SONIA MARIA ROSA

المصدر: Neurobiology of Disease
Neurobiology of Disease, Vol 81, Iss, Pp 144-153 (2015)

مصطلحات موضوعية: FAC, ferric ammonium citrate, TMRM, tetramethylrhodamine methyl ester, PKAN, pantothenate kinase associated neurodegeneration, Mitochondrion, 0302 clinical medicine, Adenosine Triphosphate, Cells, Cultured, chemistry.chemical_classification, Aconitate Hydratase, Membrane Potential, Mitochondrial, Neurons, DFO, deferoxamine, RPA, rhodamine B-[(1,10-phenanthroline-5-yl)-aminocarbonyl]benzyl ester, 0303 health sciences, NBIA, Neurodegeneration, PIH, pyridoxal isonicotinoyl hydrazone, Neurodegenerative Diseases, Iron metabolism, Glutathione, Cell biology, Mitochondria, Phosphotransferases (Alcohol Group Acceptor), Biochemistry, Neurology, NBIA, neurodegeneration with brain iron accumulation, Reactive oxygen specie, Fibroblast, IRP1, iron regulatory protein 1, Oxidation-Reduction, Human, Adult, LIP, labile iron pool, Iron, Oxidative phosphorylation, Biology, RPAC, rhodamine B-[(phenanthren-9-yl)-aminocarbonyl]-benzylester, Aconitase, Pantothenate kinase-associated neurodegeneration, Article, lcsh:RC321-571, 03 medical and health sciences, ROS, reactive oxygen species, iNs, induced neurons, Induced neuron, medicine, Humans, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, 030304 developmental biology, Reactive oxygen species, Analysis of Variance, Neurodegenerative Disease, DHR-123, dihydrorhodamine 123, Induced neurons, Infant, Newborn, Neuron, Fibroblasts, medicine.disease, PANK2, Lip, Cytosol, chemistry, DCF, dichlorofluorescein, Mutation, Energy Metabolism, 030217 neurology & neurosurgery

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47111460d6c550971554646d7eadd0e6Test