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1
المؤلفون: Xi Lu, Xiaohong Sang, Han Wu, Wei Hong, Jing Pang, Peng Wang, Yue Li, Ouyang Yifan, Tongying Nie, Hong-Tong Chen, Xue Li, Yu Huang, Yu Sun, Congran Li, Xinxin Hu, Luyao Dong, Ian C. Paterson, Guoqing Li, Xinyi Yang, Xuefu You, Yun Lu, Jian-Dong Jiang, Dong Wenting, Hao Wang, Xiukun Wang
المصدر: European Journal of Medicinal Chemistry. 228:113979
مصطلحات موضوعية: Acinetobacter baumannii, Methicillin-Resistant Staphylococcus aureus, DHPS, Microbial Sensitivity Tests, Thymidylate synthase, Vancomycin-Resistant Enterococci, Structure-Activity Relationship, chemistry.chemical_compound, Folic Acid, Enterobacteriaceae, Drug Discovery, Dihydrofolate reductase, medicine, Quinazoline, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, biology, Sulfamethoxazole, Organic Chemistry, General Medicine, Antimicrobial, Trimethoprim, Anti-Bacterial Agents, Biochemistry, chemistry, biology.protein, Folic Acid Antagonists, Dihydropteroate synthase, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa251e9d3e38beee68634889acfbc0fTest
https://doi.org/10.1016/j.ejmech.2021.113979Test -
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المؤلفون: Xiaohong Sang, Yucheng Wang, Wei Hong, Hao Wang, Xinyi Yang, Xuefu You, Meiling Chen, Ian C. Paterson
المصدر: European Journal of Medicinal Chemistry. 191:112154
مصطلحات موضوعية: Ligands, 01 natural sciences, Small Molecule Libraries, Serine, 03 medical and health sciences, Drug Development, Transforming Growth Factor beta, Drug Discovery, Animals, Humans, Receptor, 030304 developmental biology, Pharmacology, 0303 health sciences, Molecular Structure, 010405 organic chemistry, Kinase, Chemistry, Organic Chemistry, General Medicine, Ligand (biochemistry), Small molecule, 0104 chemical sciences, Cell biology, Pyrazoles, Signal transduction, Receptors, Transforming Growth Factor beta, Function (biology), Transforming growth factor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d929c29c68aee6a03860d25e180d5deTest
https://doi.org/10.1016/j.ejmech.2020.112154Test -
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المؤلفون: Hao Wang, Xuefu You, Ian C. Paterson, Yu Huang, Xinyi Yang, Yu Sun, Wei Hong, Jingyang Li, Wee Lin Wong, Han Wu, Jiajia Cui, Lee Fah Yap
المصدر: European Journal of Medicinal Chemistry. 189:112042
مصطلحات موضوعية: Benzylamines, Epithelial-Mesenchymal Transition, Ligands, 01 natural sciences, Transforming Growth Factor beta1, 03 medical and health sciences, Cell Movement, Drug Discovery, Humans, Epithelial–mesenchymal transition, Receptor, 030304 developmental biology, Pharmacology, 0303 health sciences, 010405 organic chemistry, Kinase, Chemistry, Organic Chemistry, Cell migration, General Medicine, Ligand (biochemistry), 0104 chemical sciences, Cell biology, Molecular Docking Simulation, A549 Cells, Drug Design, Phosphorylation, Signal transduction, Receptors, Transforming Growth Factor beta, Protein Binding, Signal Transduction, Transforming growth factor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962fe6db02f17aabce86e47d600985adTest
https://doi.org/10.1016/j.ejmech.2020.112042Test -
4
المؤلفون: Ian C. Paterson, Anas Saeed, Paul Murray, Victor Lopes, Stephen S. Prime, Andrew H. Sims
المصدر: Oral Oncology. 51:237-246
مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Alcohol Drinking, Microarray, Population, Gene Expression, Disease, Biology, Bioinformatics, Risk Factors, Internal medicine, medicine, Humans, education, Gene, Areca, Aged, Sri Lanka, Aged, 80 and over, education.field_of_study, Genetic heterogeneity, Gene Expression Profiling, Smoking, Middle Aged, medicine.disease, Head and neck squamous-cell carcinoma, Phenotype, United Kingdom, Gene expression profiling, Carcinoma, Squamous Cell, Mastication, Female, Mouth Neoplasms, Oral Surgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31804c0011de61cf39c4601fe6e4101Test
https://doi.org/10.1016/j.oraloncology.2014.12.004Test -
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المؤلفون: Hao Wang, Charles A. Laughton, Wei Hong, Lee Fah Yap, Ian C. Paterson, Jingyang Li
المصدر: Journal of Molecular Graphics and Modelling. 51:193-202
مصطلحات موضوعية: Protein-Arginine N-Methyltransferases, Methyltransferase, Arginine, Stereochemistry, Molecular Dynamics Simulation, Ligands, Methylation, Protein Structure, Secondary, chemistry.chemical_compound, Catalytic Domain, Materials Chemistry, Side chain, Humans, Enzyme Inhibitors, Physical and Theoretical Chemistry, Guanidine, Spectroscopy, biology, Active site, Hydrogen Bonding, Computer Graphics and Computer-Aided Design, Small molecule, Molecular Docking Simulation, Repressor Proteins, chemistry, Biochemistry, Structural Homology, Protein, biology.protein, Thermodynamics, Arginine binding, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e53374a4578dd741adc17ea9759819fcTest
https://doi.org/10.1016/j.jmgm.2014.05.010Test -
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المؤلفون: John W. Eveson, Miranda Pring, Anu Ganapathy, Nicky Price, Stephen S. Prime, Ian C. Paterson, Maria Davies, Suzy P. Threadgold
المصدر: Cancer Letters. 298:107-118
مصطلحات موضوعية: Inhibitor of Differentiation Protein 1, Cancer Research, Pathology, medicine.medical_specialty, Skin Neoplasms, Cellular differentiation, Mice, Nude, Transfection, medicine.disease_cause, Metastasis, Mice, Transforming Growth Factor beta, medicine, Animals, Humans, Neoplasm Metastasis, biology, Cancer, Cell Differentiation, Transforming growth factor beta, medicine.disease, Immunohistochemistry, Up-Regulation, Transplantation, medicine.anatomical_structure, Oncology, Carcinoma, Squamous Cell, biology.protein, Cancer research, Signal transduction, Carcinogenesis, Keratinocyte, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16739d42089aafc279052df3f7a3d8b7Test
https://doi.org/10.1016/j.canlet.2010.06.008Test -
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المؤلفون: Suzy Huntley, Stephen S. Prime, Maria Davies, Lee Fah Yap, Ian C. Paterson, C. Max Robinson, Eswary Thirthagiri
المصدر: Cancer Letters. 258:276-285
مصطلحات موضوعية: Cancer Research, Cdc20 Proteins, Blotting, Western, Cell, Aneuploidy, Cell Cycle Proteins, Spindle Apparatus, CDC20, Biology, Cell Line, Tumor, Chromosomal Instability, Chromosome instability, Mitotic Index, medicine, Humans, Centrosome, Calcium-Binding Proteins, Mouth Mucosa, Cancer, Flow Cytometry, HCT116 Cells, medicine.disease, Cell biology, Repressor Proteins, stomatognathic diseases, Spindle checkpoint, medicine.anatomical_structure, Oncology, Cell culture, Mad2 Proteins, Mouth Neoplasms, Caco-2 Cells
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f201d0e8e2dad6e165eb138f353f5b3Test
https://doi.org/10.1016/j.canlet.2007.09.008Test -
8
المصدر: Oral Oncology. 43:263-271
مصطلحات موضوعية: Male, Cancer Research, Epithelial dysplasia, Pathology, medicine.medical_specialty, Free flap, Surgical Flaps, Biomarkers, Tumor, medicine, Carcinoma, Humans, Oral mucosa, Aged, Aged, 80 and over, business.industry, Mouth Mucosa, Soft tissue, Epithelial Cells, Middle Aged, Plastic Surgery Procedures, medicine.disease, Immunohistochemistry, Ki-67 Antigen, medicine.anatomical_structure, Oncology, Dysplasia, Face, Carcinoma, Squamous Cell, Resection margin, Female, Mouth Neoplasms, Tumor Suppressor Protein p53, Oral Surgery, business, Precancerous Conditions, Stratum basale
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1713a2bf6aa66498c2bde929cb4529Test
https://doi.org/10.1016/j.oraloncology.2006.03.013Test -
9
المؤلفون: Gary J. Macfarlane, Susanne M. Gollin, Edwina McGlinn, Chelsee Hewitt, Peter R. Wilson, Nalin Thakker, Kenneth K Parkinson, R.T.M. Woodwards, Ian C. Paterson, Anne Papageorgiou, Philip Sloan, Andrew P. Read
المصدر: Cancer Letters. 209:207-213
مصطلحات موضوعية: Cancer Research, Tumor suppressor gene, Loss of Heterozygosity, Locus (genetics), Biology, Loss of heterozygosity, Tumor Cells, Cultured, medicine, Humans, Gene silencing, Gene, Polymorphism, Genetic, Tumor Suppressor Proteins, GTPase-Activating Proteins, medicine.disease, Head and neck squamous-cell carcinoma, Molecular biology, Oncology, Head and Neck Neoplasms, Chromosome Arm, Mutation, Carcinoma, Squamous Cell, DLC1, Chromosome Deletion, Chromosomes, Human, Pair 8, Microsatellite Repeats
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13af4e0eec04c00618c10fae31cc407eTest
https://doi.org/10.1016/j.canlet.2003.12.018Test -
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المؤلفون: Stephen S. Prime, Ian C. Paterson, David Dawbarn, Mark S. Fahey, Shelley J Allen
المصدر: Analytical Biochemistry. 290:272-276
مصطلحات موضوعية: TGF alpha, Biophysics, Enzyme-Linked Immunosorbent Assay, Protein Serine-Threonine Kinases, Biology, Binding, Competitive, Polymerase Chain Reaction, Biochemistry, law.invention, Transforming Growth Factor beta1, Transforming Growth Factor beta3, Transforming Growth Factor beta, law, Extracellular, Humans, Receptor, Molecular Biology, Protease-activated receptor 2, Receptor, Transforming Growth Factor-beta Type II, Cell Biology, TGF beta receptor 2, Fusion protein, Recombinant Proteins, Protein Structure, Tertiary, Kinetics, Recombinant DNA, Receptors, Transforming Growth Factor beta, Transforming growth factor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927181d2e2dd30c3fe5830e559d35ca9Test
https://doi.org/10.1006/abio.2000.4948Test