المؤلفون: Francesco Musumeci, Antonio Giovanni Cammardella, Andrea Montalto, Carmine Musto, Vincenzo Polizzi, Federico Ranocchi, Mauro Cassese, Antonio Lio, Marina Comisso, Vitaliano Buffa

المصدر: The Annals of Thoracic Surgery. 110:e365-e367

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Premature aging, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Transcatheter aortic, medicine.medical_treatment, Disease, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Valve replacement, Internal medicine, medicine, Progeria, integumentary system, business.industry, nutritional and metabolic diseases, medicine.disease, Stenosis, 030228 respiratory system, Aortic valve stenosis, Cardiology, Surgery, Cardiology and Cardiovascular Medicine, business, Hutchinson Gilford Progeria Syndrome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a6bd7b95b5906cc5039fb7e952d1f7f0Test
https://doi.org/10.1016/j.athoracsur.2020.03.067Test

المؤلفون: Hanne Leysen, Jhana O. Hendrickx, Paula Santos-Otte, Stuart Maudsley, Jaana van Gastel, Bronwen Martin

المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 1265-1277 (2019)

مصطلحات موضوعية: Aging, Review Article, Disease, Aging disorders, Biochemistry, vascular smooth muscle cells, (VSMC), cyclin-dependent kinase inhibitor 1, (cdkn1A/p21), 0302 clinical medicine, Structural Biology, Hutchinson–Gilford progeria syndrome, (HGPS), purinergic receptors family, (P2Y), protein kinases, (PK), beta2-adrenergic receptor, (β2AR), Receptor, endothelial cell differentiation gene, (Edg), nuclear factor kappa-light-chain-enhancer of activated B cells, (NF- κβ), senescence associated secretory phenotype, (SASP), 0303 health sciences, Relaxin family receptor 3, (RXFP3), tumor suppressor gene PTEN, (PTEN), transcription factor E2F3, (E2F3), Computer Science Applications, Cell biology, retinoblastoma, (RB), Chemistry, 030220 oncology & carcinogenesis, G protein-coupled receptor kinase, (GRK), latent semantic indexing, (LSI), Lysophosphatidic acid, (LPA), G protein-coupled receptors (GPCRs), G protein-coupled receptor kinase interacting protein 2 (GIT2), mitogen-activated protein kinase, (MAPK), Regulator of G-protein signaling, (RGS), Engineering sciences. Technology, AT1R blockers, (ARB), Biotechnology, Cell signaling, lcsh:Biotechnology, renin-angiotensin system, (RAS), Biophysics, Cellular senescence, tumor suppressor protein 53, (p53), Biology, 03 medical and health sciences, Cell surface receptor, lcsh:TP248.13-248.65, angiotensin type 2 receptor, (AT2R), Genetics, G protein-coupled receptor kinase interacting protein 2, (GIT2), Ataxia telangiectasia mutated, (ATM), Angiotensin II, (Ang II), 030304 developmental biology, G protein-coupled receptor, inactive state, (R), angiotensin type 1 receptor, (AT1R), G protein-coupled receptors, (GPCRs), β-Arrestin, ADP-ribosylation factor GTPase-activating protein, (Arf-GAP), cyclin-dependent kinase 2, (CDK2), Apoptosis, transmembrane, (TM), stress-induced premature senescence, (SIPS), active state, (R*)

وصف الملف: pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df108c2d57f738f31f95e73a11100b3Test
https://doi.org/10.1016/j.csbj.2019.08.005Test

المؤلفون: Isotta Cainero, Nicholas Anthony, Alberta Trianni, Alberto Diaspro

المصدر: Biophysical Journal. 120:180a-181a

مصطلحات موضوعية: Pathology, medicine.medical_specialty, business.industry, Biophysics, Medicine, business, Hutchinson Gilford Progeria Syndrome, Ptychography

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b948ff2355629d9ab8f4d04c97c3a24Test
https://doi.org/10.1016/j.bpj.2020.11.1258Test

المؤلفون: Gesson, Kevin, Vidak, Sandra, Foisner, Roland

المصدر: Seminars in Cell & Developmental Biology

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, BAF, barrier-to-autointegration factor, MDPSC, muscle-derived stem/progenitor cells, animal structures, ESC, embryonic stem cell, LEM, LAP2-Emerin-Man1, MSC, mesenchymal stem cell, Review, Nuclear envelopathies, FPLD, familial partial lipodystrophy, Retinoblastoma Protein, Muscular Dystrophies, Nuclear envelope, LAD, lamina-associated domain, Mice, Progeria, LAP, lamina-associated polypeptide, Animals, Humans, Nucleoplasmins, Dam, DNA adenine methyltransferase, DCM, dilated cardiomyopathy, Cell Proliferation, Adult stem cells, pRb, retinoblastoma protein, integumentary system, Laminopathies, INM, inner nuclear membrane, Membrane Proteins, Aging, Premature, Cell Differentiation, Cell Biology, Lamin Type A, Chromatin, Lamins, HGPS, Hutchinson–Gilford Progeria Syndrome, DNA-Binding Proteins, stomatognathic diseases, EDMD, Emery Dreifuss muscular dystrophy, Gene Expression Regulation, iPS, induced pluripotent stem cell, embryonic structures, ASC, (somatic) adult stem cell, NE, nuclear envelope, Self-renewal, LRD, lamin rich domain, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fb352e8dfe077ede289c26cbbb47c377Test

المؤلفون: Pablo Cabezas-Sanchez, Jose L. Luque-Garcia, José Antonio Enríquez, Diego Megias, Carlos López-Otín, Fernando G. Osorio, Vicente Andrés, José Rivera-Torres, Carmen Cámara, Rebeca Acín-Pérez, Cristina González-Gómez

المساهمون: Ministerio de Economía y Competitividad (España), Instituto de Salud Carlos III, Progeria Research Foundation, Comunidad de Madrid (España), Ministerio de Educación (España), Fundación ProCNIC, Fundación Cajastur

المصدر: Repisalud
Instituto de Salud Carlos III (ISCIII)

مصطلحات موضوعية: Male, Proteomics, Ribosomal protein S6 kinase, 70kDa, polypeptide 1, ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide, ATP5B, Molecular biology of aging, ENO2, Pyruvate kinase, muscle, ATP5F1, Zoledronic Acid, SILAC, Biochemistry, Progerin, LMNA, Mice, Adenosine Triphosphate, Methionine, Progeria, cytochrome c oxidase, Amino Acids, Stable isotope labeling with amino acids in cell culture, Child, p70S6K, Pravastatin, Skin, Mammalian target of rapamycin, Diphosphonates, integumentary system, Imidazoles, ATP5O, Nuclear Proteins, Lamin Type A, MAF, OXPHOS, PKM, Mitochondria, Cell biology, ATP5A1, FTI, mTOR, HGPS, eIF2, Female, eIF4, Flavoprotein subunit of succinate dehydrogenase, CS, Accelerated aging, Premature aging, Senescence, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, Biophysics, Mouse adult fibroblast, ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide, Biology, ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit, ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1, Oxygen Consumption, Eukaryotic translation initiation factor 2, Zinc metalloproteinase STE24 homolog, Eukaryotic translation initiation factor 4, ATP5C1, medicine, Animals, Humans, Zmpste24, Oxidative phosphorylation, Protein Precursors, Hutchinson–Gilford progeria syndrome, Enolase 2, COX, Galactose, nutritional and metabolic diseases, Fibroblasts, medicine.disease, Molecular biology, Glucose, ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, Farnesyltransferase inhibitor, Gene Expression Regulation, Mutation, Lamin A, FpSDH, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Mitochondrial dysfunction, citrate synthase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24117d78cec99c4c6de03d292e120926Test
https://doi.org/10.1016/j.jprot.2013.08.008Test

المؤلفون: Marina Mahynski, Tom Misteli

المصدر: Biophysical Journal. 114:445a

مصطلحات موضوعية: 0301 basic medicine, Premature aging, medicine.medical_specialty, Mitochondrial DNA, business.industry, Biophysics, Disease, 03 medical and health sciences, 030104 developmental biology, Endocrinology, Internal medicine, Medicine, business, Hutchinson Gilford Progeria Syndrome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::9ce8c2ec0a79e0d510cafe031c66614cTest
https://doi.org/10.1016/j.bpj.2017.11.2462Test

المؤلفون: J.A. Stockman

المصدر: Yearbook of Pediatrics. 2009:485-487

مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.industry, Internal medicine, Disease progression, Medicine, business, Hutchinson Gilford Progeria Syndrome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0be58ec749a8adeb67dee8a8bae03fa6Test
https://doi.org/10.1016/s0084-3954Test(08)79188-7

المؤلفون: Li Tang, Hui Zhang, Jianying Liang, Xilan Chen, Yifeng Guo, Zhirong Yao, Hong Yu

المصدر: Journal of the American Academy of Dermatology. 69:e175-e176

مصطلحات موضوعية: LMNA, Genetics, business.industry, Mutation (genetic algorithm), Medicine, Dermatology, business, Hutchinson Gilford Progeria Syndrome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e63aadd63ce0add7949473e3b1999515Test
https://doi.org/10.1016/j.jaad.2011.07.002Test

المؤلفون: B.H. Thiers

المصدر: Yearbook of Dermatology and Dermatologic Surgery. 2007:227-228

مصطلحات موضوعية: Genetics, business.industry, Mutation (genetic algorithm), Farnesyltransferase inhibitor, Cancer research, Medicine, Clinical phenotype, business, Hutchinson Gilford Progeria Syndrome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::547663bf20c990224d08bc863694163aTest
https://doi.org/10.1016/s0093-3619Test(08)70518-5

المؤلفون: Samim Özen, Aslihan Kiraz

المصدر: Current Opinion in Biotechnology. 22:S105

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Biomedical Engineering, Medicine, Bioengineering, business, Hutchinson Gilford Progeria Syndrome, Dermatology, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2f076df5c154cf4598d4627d562ae0dbTest
https://doi.org/10.1016/j.copbio.2011.05.332Test