المؤلفون: Fumiya Tao, Sanshiro Hanada, Kazuya Matsushima, Hiroshi Arakawa, Naoki Ishida, Yukio Kato, Saya Okimura, Tomohisa Watanabe, Nobuhiko Kojima

المصدر: Journal of Bioscience and Bioengineering. 135:134-142

مصطلحات موضوعية: Bioengineering, Applied Microbiology and Biotechnology, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f398befef5979d85de055f675cb09bb0Test
https://doi.org/10.1016/j.jbiosc.2022.10.006Test

المؤلفون: Yusuke Masuo, Hiroshi Arakawa, Yukio Kato, Noritaka Nakamichi, Takumi Kawanishi

المصدر: Journal of Pharmaceutical Sciences. 108:3130-3137

مصطلحات موضوعية: Male, ATP Binding Cassette Transporter, Subfamily B, medicine.drug_class, Administration, Oral, Pharmaceutical Science, 02 engineering and technology, Pharmacology, digestive system, 030226 pharmacology & pharmacy, Intestinal absorption, Tyrosine-kinase inhibitor, Mice, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Oral administration, medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, Animals, Humans, Intestinal Mucosa, Cholestasis, Intestinal permeability, Microvilli, Chemistry, Bile duct, Cell Membrane, Imatinib, 021001 nanoscience & nanotechnology, medicine.disease, Up-Regulation, Disease Models, Animal, medicine.anatomical_structure, Intestinal Absorption, Imatinib Mesylate, Administration, Intravenous, 0210 nano-technology, Tyrosine kinase, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4379142fc0d1120bf3cd16514e184426Test
https://doi.org/10.1016/j.xphs.2019.05.017Test

المؤلفون: Ikumi Tamai, Shiho Nedachi, Ikumi Washio, Naoki Ishiguro, Takeo Nakanishi, Angelina Yukiko Staub, Hiroshi Arakawa, Hikaru Kubo

المصدر: Journal of Pharmaceutical Sciences. 108:2798-2804

مصطلحات موضوعية: Male, ATP Binding Cassette Transporter, Subfamily B, Organic Cation Transport Proteins, Pharmaceutical Science, 02 engineering and technology, Pharmacology, Kidney, Peptide Transporter 1, 030226 pharmacology & pharmacy, Kidney Tubules, Proximal, 03 medical and health sciences, chemistry.chemical_compound, Sodium-Glucose Transporter 1, 0302 clinical medicine, medicine, Animals, Humans, Pharmacokinetics, Carnitine, Rats, Wistar, Zosuquidar, Symporters, Reabsorption, Biological Transport, Transporter, Apical membrane, 021001 nanoscience & nanotechnology, Rats, HEK293 Cells, medicine.anatomical_structure, Pharmaceutical Preparations, chemistry, Ergothioneine, Efflux, 0210 nano-technology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773f701e332e9832876352ae3b400ed3Test
https://doi.org/10.1016/j.xphs.2019.03.031Test

المؤلفون: Mathieu Danoy, Stéphane Poulain, Benedikt Scheidecker, Rachid Jellali, Yannick Tauran, Marjorie Leduc, Johanna Bruce, Francoise Gilard, Bertrand Gakiere, Hiroshi Arakawa, Yukio Kato, Soo Hyeon Kim, Taketomo Kido, Atsushi Miyajima, Yasuyuki Sakai, Eric Leclerc

المساهمون: Institute of Industrial Science (IIS), The University of Tokyo (UTokyo), Graduate School of Engineering [The Univ of Tokyo] (UTokyo), Biomécanique et Bioingénierie (BMBI), Université de Technologie de Compiègne (UTC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire des Multimatériaux et Interfaces (LMI), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Plateforme protéomique 3P5 [Institut Cochin] (3P5), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut des Sciences des Plantes de Paris-Saclay (IPS2 (UMR_9213 / UMR_1403)), Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Kanazawa University (KU), Laboratory for Integrated Micro Mechatronics Systems (LIMMS), The University of Tokyo (UTokyo)-Centre National de la Recherche Scientifique (CNRS), Japan Society for the Promotion of Science (JSPS) Grant-in-aid for Scientific Research (S) 16H06328., ANR-16-RHUS-0005,iLite,iLite(2016), Université Paris Cité, Equipe HAL, iLite - - iLite2016 - ANR-16-RHUS-0005 - RHUS - VALID

المصدر: Biochemical Engineering Journal
Biochemical Engineering Journal, 2022, 181, pp.108408. ⟨10.1016/j.bej.2022.108408⟩

مصطلحات موضوعية: Proteomics, Environmental Engineering, Biomedical Engineering, Bioengineering, Hepatocyte like cells, Nanocage, Induced pluripotent stem cells, Liver, Carboxypeptidase M, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, Metabolomics, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Transcriptomics, Organ on chip, Biotechnology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c11551f21a74a4e7508a12ffe69d5fTest
https://doi.org/10.1016/j.bej.2022.108408Test

المؤلفون: Ikumi Tamai, Hiroshi Arakawa, Saki Omote

المصدر: Journal of Pharmaceutical Sciences. 106:2899-2903

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Pyridines, medicine.drug_class, Pharmaceutical Science, Renal function, Kidney, Tyrosine-kinase inhibitor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Crizotinib, Internal medicine, medicine, Humans, Secretion, Protein Kinase Inhibitors, Creatinine, Organic cation transport proteins, biology, HEK 293 cells, Organic Cation Transporter 2, Biological Transport, Transporter, Kinetics, HEK293 Cells, 030104 developmental biology, Endocrinology, chemistry, 030220 oncology & carcinogenesis, biology.protein, Pyrazoles, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f26ee572da1825321c06138c0ba0597Test
https://doi.org/10.1016/j.xphs.2017.03.013Test

المؤلفون: Hiroshi Arakawa, Miki Nakajima, Kenji Mishiro, Yongjie Zhang, Masataka Nakano, Hiroki Hashizume, Kanji Mishima, Tatsuki Fukami

المصدر: Biochemical Pharmacology. 183:114303

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Ketoprofen, Adolescent, Mefenamic acid, Coenzyme A, Flurbiprofen, Glucuronidation, Spodoptera, Pharmacology, Biochemistry, Gene Expression Regulation, Enzymologic, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Coenzyme A Ligases, Sf9 Cells, medicine, Animals, Humans, Aged, Liver injury, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Loxoprofen, Middle Aged, medicine.disease, Isoenzymes, 030104 developmental biology, Liver, 030220 oncology & carcinogenesis, Female, Glucuronide, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010e70df300ff96b9b6eebce68f6c88dTest
https://doi.org/10.1016/j.bcp.2020.114303Test

المؤلفون: Nobuhiro Nitta, Kentaro Yano, Takumi Kawanishi, Takuya Kumamoto, Yukio Kato, Hiroyuki Yamada, Eiko Matsumoto, Hiroshi Arakawa, Kazutaka Arai, Takuo Ogihara, Ichio Aoki, Sayaka Shibata

المصدر: International Journal of Pharmaceutics. 586:119575

مصطلحات موضوعية: Tumor imaging, chemistry.chemical_classification, Biodistribution, Trifluoromethyl, medicine.diagnostic_test, Chemistry, Pharmaceutical Science, Magnetic resonance imaging, Peptide, Transporter, 02 engineering and technology, 021001 nanoscience & nanotechnology, Cleavage (embryo), 030226 pharmacology & pharmacy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, medicine, Biophysics, 0210 nano-technology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::65baa48cc3197f00796c2b1b50a7484cTest
https://doi.org/10.1016/j.ijpharm.2020.119575Test

المؤلفون: Takuo Ogihara, Kaori Morimoto, Taichi Ohmachi, Kiko Ichiba, Yoko Idota, Masahiko Kanagawa, Hiroki Kamioka, Takumi Tomono, Yasuko Hatano, Kentaro Yano, Hiroshi Arakawa

المصدر: Journal of Pharmaceutical Sciences. 105:339-342

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Nifedipine, Sensory Receptor Cells, Cmax, Glutamic Acid, Pharmaceutical Science, Peptide Transporter 1, Intestinal absorption, 03 medical and health sciences, chemistry.chemical_compound, D-Glucose, Oral administration, Internal medicine, medicine, Animals, Mannitol, Channel blocker, Rats, Wistar, Cephalexin, Membranes, Symporters, biology, Chemistry, digestive, oral, and skin physiology, Peptide transporter 1, Glutamic acid, Calcium Channel Blockers, Taste Buds, Rats, Protein Transport, Glucose, Jejunum, 030104 developmental biology, Endocrinology, Intestinal Absorption, biology.protein, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0656ce915a6a7b9bafc2c6450537c0Test
https://doi.org/10.1016/j.xphs.2015.11.024Test

المؤلفون: Yukio Kato, Takumi Kawanishi, Hiroshi Arakawa, Yusuke Masuo

المصدر: Drug Metabolism and Pharmacokinetics. 35:S92

مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Cholestasis, business.industry, Internal medicine, medicine, Pharmaceutical Science, Pharmacology (medical), Imatinib, medicine.disease, business, Gastroenterology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c9c3619be2573daeed1690a7eff936b4Test
https://doi.org/10.1016/j.dmpk.2020.04.231Test

المؤلفون: Masayuki Seki, Takuya Abe, Masamichi Ishiai, Takemi Enomoto, Minoru Takata, Hiroshi Arakawa, Weidong Wang, Yutaka Ishii, Shunichi Takeda, M. Nurul Islam, Yoshifumi Hosono

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1843(5):1002-1012

مصطلحات موضوعية: ICL repair, genetic processes, RAD51, Article, Cell Line, RecQL5, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Animals, Rad51 filament, Genes, Tumor Suppressor, Gene conversion, Gene, Molecular Biology, Gene knockout, 030304 developmental biology, Recombination, Genetic, 0303 health sciences, RecQ Helicases, biology, Helicase, Tumor suppressor, DNA, Cell Biology, BRCA2, Molecular biology, 3. Good health, enzymes and coenzymes (carbohydrates), chemistry, Cell culture, Fanconi anemia, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, health occupations, biology.protein, Homologous recombination, Chickens

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483cfebf99c7df5b34073dd146b93c3cTest