نتائج البحث - "Activation-induced (cytidine) deaminase"

1

Mechanisms underpinning poor antibody responses to vaccines in ageing

المؤلفون: Jia Le Lee, Michelle A. Linterman

المصدر: Immunology Letters

مصطلحات موضوعية: Aging, Cell type, Stromal cell, Longevity, Immunology, Antibody Affinity, B-Lymphocyte Subsets, T cells, Vaccine Efficacy, Tfh, T follicular helper, FCRL5, Fc receptor-like 5, FRC, Follicular reticular cell, Biology, GC, Germinal centre, Affinity maturation, Immune system, BCR, B cell receptor, Tfr, T follicular regulatory, IgVH, Heavy chain variable domain of immunoglobulin, AID, Activation-induced cytidine deaminase, Humans, Immunology and Allergy, ICOS, Inducible T-cell costimulator, cTfh, Circulating T follicular helper, Aged, MHC, Major histocompatibility complex, IFN-I, Type I interferon, B cells, Invited Review, CRC, CXCL12-producing reticular cell, Germinal centre, Follicular dendritic cells, TCR, T cell receptor, Vaccination, ABC, Atypical/age-associated B cell, Germinal Center, Treg, Regulatory T cell, Vaccine efficacy, Immunity, Humoral, Ageing, CDR3, Complementarity determining 3 region, SHM, Somatic hypermutation, FDC, Follicular dendritic cell, cDC1, Type I conventional dendritic cell, biology.protein, Antibody, Vaccine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323f132317546bf6bbf077cfb9b39d0aTest
https://doi.org/10.1016/j.imlet.2021.11.001Test

2

Aicda deficiency exacerbates high-fat diet-induced hyperinsulinemia but not gut dysbiosis in mice

المؤلفون: Yurika Takase, Takeshi Tsuruta, Shiori Himoto, Kei Sonoyama, Qui D. Nguyen, Emiko Katsumata, Teresia Aluoch Muhomah, Aoi Nishijima, Naoki Nishino

المصدر: Nutrition Research. 93:15-26

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a116ffd73a3a6f2cc2e4739a396474Test
https://doi.org/10.1016/j.nutres.2021.06.009Test

3

AID assists DNMT1 to attenuate BCL6 expression through DNA methylation in diffuse large B-cell lymphoma cell lines

المؤلفون: Mingzhe Zheng, Junna Jiao, Woodvine Otieno Odhiambo, Zhuangwei Lv, Xiaozhuo Yu, Meng Yuan, Yunfeng Ma, Ping Zhang, Yanhong Ji, Hua Zhang, Yang Wang

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 3, Pp 142-153 (2020)

مصطلحات موضوعية: DNA (Cytosine-5-)-Methyltransferase 1, 0301 basic medicine, Original article, Cancer Research, lcsh:RC254-282, Models, Biological, Proto-Oncogene Mas, Mice, 03 medical and health sciences, 0302 clinical medicine, Genes, Reporter, immune system diseases, Cell Line, Tumor, Cytidine Deaminase, hemic and lymphatic diseases, medicine, Activation-induced (cytidine) deaminase, Animals, Humans, Promoter Regions, Genetic, BCL6 repression, DNA methylation, biology, Gene Expression Regulation, Leukemic, Chemistry, DNA methyltransferase 1, Germinal center, Diffuse large B-cell lymphoma, Cytidine deaminase, Methylation, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, BCL6, DNA-Binding Proteins, Disease Models, Animal, 030104 developmental biology, 030220 oncology & carcinogenesis, Proto-Oncogene Proteins c-bcl-6, Cancer research, DNMT1, biology.protein, Lymphoma, Large B-Cell, Diffuse, Activation-induced cytidine deaminase, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2db24087849265dbb989ae25333fc4Test
https://doi.org/10.1016/j.neo.2020.01.002Test

4

IL-21 and IL-5 coordinately induce surface IgA+ cells

المؤلفون: Masaaki Hashiguchi, Tetsuji Kobata, Hidefumi Kojima, Yumiko Kanno, Yuji Kashiwakura

المصدر: Immunology Letters. 224:21-27

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3bfe38951f9499b4e1b3b40288b99917Test
https://doi.org/10.1016/j.imlet.2020.05.004Test

5

Splicing regulator SRSF1-3 that controls somatic hypermutation of IgV genes interacts with topoisomerase 1 and AID

المؤلفون: Anshu Agarwal, Ankit Jaiswal, Amit Kumar Singh, Anubhav Tamrakar, Prashant Kodgire, Prabhanshu Tripathi, Naoki Kanayama

المصدر: Molecular Immunology. 116:63-72

مصطلحات موضوعية: 0301 basic medicine, RNA Splicing, In silico, Immunology, Regulator, Somatic hypermutation, Proximity ligation assay, Cell Line, Mice, 03 medical and health sciences, 0302 clinical medicine, Cytidine Deaminase, Activation-induced (cytidine) deaminase, Animals, Immunoprecipitation, Protein Isoforms, Amino Acid Sequence, Molecular Biology, Cell Nucleus, B-Lymphocytes, Genes, Immunoglobulin, Serine-Arginine Splicing Factors, biology, Cytidine deaminase, Immunoglobulin Class Switching, Cell biology, 030104 developmental biology, DNA Topoisomerases, Type I, RNA splicing, biology.protein, Somatic Hypermutation, Immunoglobulin, Chickens, Nuclear localization sequence, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633df14e91cff02b4d68f15dfaf3173aTest
https://doi.org/10.1016/j.molimm.2019.10.002Test

6

Regulated localization of an AID complex with E2A, PAX5 and IRF4 at the Igh locus

المؤلفون: Ramesh Kumar, Christine Grundström, Jannek Hauser, Thomas Grundström

المصدر: Molecular Immunology. 80:78-90

مصطلحات موضوعية: Transcriptional Activation, 0301 basic medicine, Chromatin Immunoprecipitation, Calmodulin, Genes, Immunoglobulin Heavy Chain, Cell- och molekylärbiologi, B-cell receptor, Immunology, Somatic hypermutation, chemical and pharmacologic phenomena, Biology, Real-Time Polymerase Chain Reaction, Antibodies, E2A, Mice, 03 medical and health sciences, immune system diseases, Cytidine Deaminase, hemic and lymphatic diseases, Basic Helix-Loop-Helix Transcription Factors, Activation-induced (cytidine) deaminase, Transcription factors, Animals, Transcription factor, Molecular Biology, B-Lymphocytes, PAX5 Transcription Factor, breakpoint cluster region, hemic and immune systems, Cytidine deaminase, Flow Cytometry, Immunoglobulin Class Switching, Molecular biology, Class switch recombination, 030104 developmental biology, Interferon Regulatory Factors, biology.protein, PAX5, Somatic Hypermutation, Immunoglobulin, Cell and Molecular Biology, Activation-induced cytidine deaminase

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12d6f15e6d92c8c204a7c99170a34a3Test

7

R-Loop Depletion by Over-expressed RNase H1 in Mouse B Cells Increases Activation-Induced Deaminase Access to the Transcribed Strand without Altering Frequency of Isotype Switching

المؤلفون: Hyongi Chon, Robert W. Maul, Kiran Sakhuja, Robert J. Crouch, Patricia J. Gearhart, Lina A. Gugliotti, Susana M. Cerritelli

المصدر: Journal of Molecular Biology. 429:3255-3263

مصطلحات موضوعية: Male, 0301 basic medicine, R-loop, RNase P, Ribonuclease H, Somatic hypermutation, Mice, Transgenic, Biology, Article, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Structural Biology, Cytidine Deaminase, Activation-induced (cytidine) deaminase, Animals, DNA Breaks, Double-Stranded, RNase H, Molecular Biology, Recombination, Genetic, B-Lymphocytes, Cytidine deaminase, Immunoglobulin Class Switching, Molecular biology, Immunoglobulin Isotypes, Mice, Inbred C57BL, 030104 developmental biology, chemistry, Immunoglobulin class switching, biology.protein, Nucleic Acid Conformation, Female, Somatic Hypermutation, Immunoglobulin, 030217 neurology & neurosurgery, DNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b09f3ad15104c1e5c75bd6f0298a17bTest
https://doi.org/10.1016/j.jmb.2016.12.020Test

8

Do ectothermic vertebrates have a home in which to affinity mature their antibody responses?

المؤلفون: A. Muthupandian, D. Waly, Brad G. Magor

المصدر: Developmental & Comparative Immunology. 119:104021

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177fd719ed4116448523bcc022fc453bTest
https://doi.org/10.1016/j.dci.2021.104021Test

9

The contributory role of lymphocyte subsets, pathophysiology of lymphopenia and its implication as prognostic and therapeutic opportunity in COVID-19

المؤلفون: Atieh Pourbagheri-Sigaroodi, Naeimeh Tavakolinia, Nader Bagheri, Mahda Delshad, Davood Bashash, Ava Safaroghli-Azar

المصدر: International Immunopharmacology

مصطلحات موضوعية: 0301 basic medicine, NKG2D, Natural killer G2D, GrB, Granzyme B, GrA, Granzyme A, Lymphocyte, MAPK, Mitogen-activated protein kinase, FoxP3, Forkhead box P3, Review, Disease, Ig, Immunoglobulin, medicine.disease_cause, 0302 clinical medicine, AID, Activation-induced cytidine deaminase, TNF-α, Tumor necrosis factor-α, Immunology and Allergy, PLR, Platelet to lymphocyte ratio, IL, Interleukin, Lymphocytes, SP, Spike protein, Coronavirus, DI, Dengue infection, TCR, T cell receptor, ALC, Atypical lymphocytes, Prognosis, FACS, Fluorescence-activated cell sorting, Pathophysiology, ICS, Intracellular cytokine staining, NK cell, Natural killer cell, ICU, Intensive care unit, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Bcl-6, B cell lymphoma 6, CRP, C-reactive protein, medicine.symptom, JAK, Janus kinase, ADE, Antibody-dependent enhancement, SOS1, Son of sevenless homolog 1, TIM-3, T cell immunoglobulin and mucin domain-3, BALF, Broncho alveolar lavage fluid, PD-1, Programmed cell death protein 1, CM T cell, Central memory T cells, Immunology, CAR-NK, Chimeric antigen receptor-engineered NK cell, EM T cell, Effector memory T cells, NKG2A, Natural killer G2A, Tregs, Regulatory T cells, SARS-CoV, Severe acute respiratory syndrome coronavirus, cTFH, Circulating follicular helper T cells, WHO, World health organization, 03 medical and health sciences, Immune system, Pharmacotherapy, Lymphopenia, ACE2, Angiotensin-converting enzyme 2, ARDS, Acute respiratory distress syndrome, TH1, T helper type 1, medicine, Humans, TLM, Time to lymphocyte model, AHF, Acute heart failure, SGLT2, Sodium-glucose cotransporter-2, ComputingMethodologies_COMPUTERGRAPHICS, Pharmacology, SARS-CoV-2, STAT, Signal transducer and activator of transcription, Septic shock, business.industry, Organ dysfunction, COVID-19, PB, Peripheral blood, COVID-19, Coronavirus disease-19, MSCs, Mesenchymal stem cells, NLR, Neutrophil to lymphocyte ratio, TFH, T follicular helper cells, medicine.disease, Lymphocyte Subsets, COVID-19 Drug Treatment, FasL, Fas ligand, 030104 developmental biology, MHC-II, Major histocompatibility complex-class II, sCD25, Soluble CD25 (interleukin-2 receptor), RBD, Receptor-binding domain, AIM assays, Analysis of activation induced marker, business, IL-2Ra, Interleukin-2 receptor alpha

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f78f67d0c68b921a80f4b5ea06dea9Test
https://doi.org/10.1016/j.intimp.2021.107586Test

10

Activation of TNF-α-AID axis and co-inhibitory signals in coordination with Th1-type immunity in a mouse model recapitulating hepatitis B

المؤلفون: Shigeru Kawakami, Ken Takahashi, Tadashi Inuzuka, Tomonori Matsumoto, Soo Ki Kim, Tsutomu Chiba, Hiroshi Seno, Hiroyuki Marusawa, Tomoaki Kurosaki

المصدر: Antiviral Research. 139:138-145

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6347cb559df28baaa4dea9c58bae2dTest
https://doi.org/10.1016/j.antiviral.2017.01.004Test

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