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المؤلفون: Yong Sup Lee, Ahmed Elkamhawy, Hwi-Ho Lee, Eun Joo Roh, Ahmed H.E. Hassan, Ji-Sun Shin, Sora Paik, Kyung-Tae Lee
المصدر: Bioorganic Chemistry. 86:112-118
مصطلحات موضوعية: Lipopolysaccharides, Cell Survival, medicine.drug_class, Inflammation, Nitric Oxide, 01 natural sciences, Biochemistry, Anti-inflammatory, Nitric oxide, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Animals, Humans, Benzamide, Protein Kinase Inhibitors, Molecular Biology, IC50, EGFR inhibitors, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Macrophages, Anti-Inflammatory Agents, Non-Steroidal, Organic Chemistry, Cancer, medicine.disease, Amides, 0104 chemical sciences, ErbB Receptors, 010404 medicinal & biomolecular chemistry, Pyrimidines, RAW 264.7 Cells, chemistry, Benzamides, Cancer research, Cytokines, medicine.symptom, Lead compound
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088272dc854baa923e5135c9311a29ebTest
https://doi.org/10.1016/j.bioorg.2019.01.017Test -
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المؤلفون: Taha F.S. Ali, Gamal El-Din A. Abuo-Rahma, Mohamed Ramadan, Mostafa H. Abdelrahman, Syed Nasir Abbas Bukhari, Mahmoud S. Abdelbaset, Mohamed Abdel-Aziz
المصدر: Bioorganic & Medicinal Chemistry. 27:1076-1086
مصطلحات موضوعية: Chalcone, Cell cycle checkpoint, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Allosteric regulation, Pharmaceutical Science, Antineoplastic Agents, Apoptosis, Carboxamide, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Chalcones, Cell Line, Tumor, Neoplasms, Drug Discovery, medicine, Humans, Moiety, Protein Kinase Inhibitors, Molecular Biology, Cell Proliferation, EGFR inhibitors, biology, 010405 organic chemistry, Organic Chemistry, Active site, 0104 chemical sciences, ErbB Receptors, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, chemistry, Drug Design, Quinolines, biology.protein, Molecular Medicine, Erlotinib, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8cef41e4b403a588af9f80a8563bb2Test
https://doi.org/10.1016/j.bmc.2019.02.012Test -
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المؤلفون: Riham F. George, Hatem A. Abdel-Aziz, Safinaz E. Abbas, Eman M. Samir, Mennatullah N. Abdelhamed
المصدر: Bioorganic Chemistry. 83:186-197
مصطلحات موضوعية: Antineoplastic Agents, Pharmacology, 01 natural sciences, Biochemistry, Cell Line, HeLa, Structure-Activity Relationship, chemistry.chemical_compound, Gefitinib, Drug Discovery, medicine, Humans, Cytotoxicity, Fibroblast, Thiazole, Protein Kinase Inhibitors, Molecular Biology, IC50, Cell Proliferation, EGFR inhibitors, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Organic Chemistry, Quinoline, biology.organism_classification, 0104 chemical sciences, ErbB Receptors, Thiazoles, 010404 medicinal & biomolecular chemistry, medicine.anatomical_structure, chemistry, Quinolines, Pyrazoles, Drug Screening Assays, Antitumor, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22f2c283c583645dcc58312799a07e8Test
https://doi.org/10.1016/j.bioorg.2018.10.038Test -
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المؤلفون: Yoshikazu Nakamura, Junko Hamamoto, Masatoshi Fujiwara, Tomoko Betsuyaku, Hiroyuki Yasuda, Yosuke Nonaka, Kenzo Soejima
المصدر: Biochemical and Biophysical Research Communications. 503:1330-1334
مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Aptamer, Biophysics, Apoptosis, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Tumor Cells, Cultured, medicine, Humans, Lung cancer, Cytotoxicity, Molecular Biology, Cell Proliferation, EGFR inhibitors, Dose-Response Relationship, Drug, Chemistry, Cell growth, Cancer, Gefitinib, Cell Biology, Aptamers, Nucleotide, medicine.disease, Receptors, Fibroblast Growth Factor, 030104 developmental biology, 030220 oncology & carcinogenesis, embryonic structures, Cancer cell, Cancer research, Fibroblast Growth Factor 2, Drug Screening Assays, Antitumor, Tyrosine kinase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0052408a8ac93120a58fa9810c8bd58Test
https://doi.org/10.1016/j.bbrc.2018.07.044Test -
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المؤلفون: Kaushal P. Patel, Sanjay Singh, Vishal Unadkat, Paranjay Parikh, Vinod Sanna, Shishir Rohit
المصدر: Bioorganic Chemistry. 117:105459
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Organic Chemistry, Drug Discovery, Rational design, Oxadiazole, Molecular Biology, Biochemistry, Combinatorial chemistry, EGFR inhibitors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::04f153efc6c977ca15ab4c667b968f59Test
https://doi.org/10.1016/j.bioorg.2021.105459Test -
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المصدر: Bioorganic Chemistry. 116:105318
مصطلحات موضوعية: Cell cycle checkpoint, Pyridines, Stereochemistry, Antineoplastic Agents, Apoptosis, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Gefitinib, Cell Line, Tumor, Drug Discovery, medicine, Humans, Cytotoxicity, Protein Kinase Inhibitors, Molecular Biology, Cell Proliferation, EGFR inhibitors, Dose-Response Relationship, Drug, Molecular Structure, biology, Phenyl isothiocyanate, Cell Cycle, Organic Chemistry, Active site, In vitro, ErbB Receptors, Pyrimidines, chemistry, Cell culture, Drug Design, biology.protein, Female, Drug Screening Assays, Antitumor, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57dd37710c3c4676af2a679c4d659993Test
https://doi.org/10.1016/j.bioorg.2021.105318Test -
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المؤلفون: Yi-Ting Tsai, Yung-Jen Chuang, En-Chi Liao, Shing-Jyh Chang, Yu-Shan Wei, Yi-Shiuan Wang, Wen-Hung Kuo, Chuan-Chi Shih, Ying-Jen Chen, Hsin-Yi Chen, Hong-Lin Chan, Chia-Hao Chan, Hsin-Yueh Yeo, Ji-Min Li, Zih-Yin Lai, Hsiu-Chuan Chou
المصدر: Archives of Biochemistry and Biophysics. 647:10-32
مصطلحات موضوعية: Proteomics, 0301 basic medicine, Cell cycle checkpoint, Proteome, DNA repair, Biophysics, Antineoplastic Agents, Apoptosis, Biology, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Gefitinib, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Molecular Biology, Cell Proliferation, EGFR inhibitors, Ovarian Neoplasms, Cell growth, Cancer, Drug Synergism, Proto-Oncogene Proteins c-mdm2, medicine.disease, Tryptamines, ErbB Receptors, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Mdm2, Female, Ovarian cancer, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::397ef69a5c9b9d98394f4dbfb0ced281Test
https://doi.org/10.1016/j.abb.2018.04.004Test -
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المؤلفون: Bo Yan, Weijie Hou, Zhenhua Zhang, Yongfen Ma, Huan Sun, Yan Ren
المصدر: Bioorganic & Medicinal Chemistry. 26:1740-1750
مصطلحات موضوعية: 0301 basic medicine, Cell Survival, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Drug Discovery, Tumor Cells, Cultured, Quinazoline, Humans, Structure–activity relationship, Benzamide, Protein Kinase Inhibitors, Molecular Biology, Cell Proliferation, EGFR inhibitors, Dose-Response Relationship, Drug, Molecular Structure, Kinase, Cell growth, Organic Chemistry, ErbB Receptors, 030104 developmental biology, chemistry, Cell culture, 030220 oncology & carcinogenesis, Benzamides, Quinazolines, Microsome, Molecular Medicine, Drug Screening Assays, Antitumor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8470b5bfe5f51e904b2b0486bc04edddTest
https://doi.org/10.1016/j.bmc.2018.02.022Test -
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المصدر: Bioorganic Chemistry. 115:105226
مصطلحات موضوعية: Lung Neoplasms, Stereochemistry, Allosteric regulation, Protein Data Bank (RCSB PDB), Antineoplastic Agents, Biochemistry, Small Molecule Libraries, Free energy perturbation, Structure-Activity Relationship, T790M, chemistry.chemical_compound, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Drug Discovery, Humans, MTT assay, Protein Kinase Inhibitors, Molecular Biology, Cell Proliferation, EGFR inhibitors, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Quinoline, Small molecule, ErbB Receptors, chemistry, Drug Resistance, Neoplasm, Mutation, Quinolines, Thermodynamics, Drug Screening Assays, Antitumor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fd1ae1b0d6f39d6da4e194579a5c99Test
https://doi.org/10.1016/j.bioorg.2021.105226Test -
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المؤلفون: Xiaodong Ma, Lixue Chen, Qiang Meng, Youjun Xu, Lei Li, Zeyao Tang, Changyuan Wang, Yan Qi, Yunhao Zhang, Yanxia Li, Hunjun Sun
المصدر: Bioorganic Chemistry. 114:105045
مصطلحات موضوعية: Lung Neoplasms, Mutant, Mice, Nude, Hydroxamic Acids, 01 natural sciences, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Cell Movement, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Drug Discovery, Animals, Humans, Protein Kinase Inhibitors, Molecular Biology, IC50, Cell Proliferation, EGFR inhibitors, Biological evaluation, Binding Sites, Hydroxamic acid, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Transfection, Xenograft Model Antitumor Assays, respiratory tract diseases, 0104 chemical sciences, ErbB Receptors, G2 Phase Cell Cycle Checkpoints, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Pyrimidines, Design synthesis, Apoptosis, Drug Design, Mutation, Cancer research, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314056fe405588b33a794f09c55a4105Test
https://doi.org/10.1016/j.bioorg.2021.105045Test