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1Glycolysis and subsequent mevalonate biosynthesis play an important role in Th2 cell differentiation
المؤلفون: Yasushi Imai, Junpei Suzuki, Makoto Kuwahara, Masakatsu Yamashita, Yuichiro Yagi
المصدر: Biochemical and Biophysical Research Communications. 530:355-361
مصطلحات موضوعية: Male, 0301 basic medicine, Pyruvate dehydrogenase kinase, Cellular differentiation, Farnesyltransferase, Biophysics, Mevalonic Acid, Biochemistry, 03 medical and health sciences, Th2 Cells, 0302 clinical medicine, Animals, Anilides, Glycolysis, Receptor, Protein Kinase Inhibitors, Molecular Biology, Transcription factor, Cells, Cultured, biology, Chemistry, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Cell Differentiation, Cell Biology, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Cytokines, Protein prenylation, Protein farnesylation, Female
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c56cee89268f5ada4e30aa089e3c47Test
https://doi.org/10.1016/j.bbrc.2020.08.009Test -
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المؤلفون: Meet Patel, William P. Saunders, Melanie J. Blanden, Walter K. Schmidt, Daniel S. Hardgrove, Kiall F. Suazo, James L. Hougland, Emily R. Hildebrandt, Mark D. Distefano
المصدر: Journal of Biological Chemistry. 293:2770-2785
مصطلحات موضوعية: Models, Molecular, Proteomics, 0301 basic medicine, Saccharomyces cerevisiae Proteins, Recombinant Fusion Proteins, Farnesyltransferase, Amino Acid Motifs, Green Fluorescent Proteins, Protein Prenylation, Saccharomyces cerevisiae, Biochemistry, Substrate Specificity, 03 medical and health sciences, Prenylation, Genes, Reporter, Animals, Humans, Enzyme Inhibitors, Databases, Protein, Molecular Biology, Alkyl and Aryl Transferases, biology, Chemistry, C-terminus, Cell Biology, Rats, Protein Subunits, HEK293 Cells, 030104 developmental biology, Microscopy, Fluorescence, Proteome, Enzymology, Protein geranylgeranyltransferase type I, biology.protein, Protein farnesylation, Protein prenylation, Sequence motif
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ababbda007187fd90bf9ffc2570e8d4aTest
https://doi.org/10.1074/jbc.m117.805770Test -
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المؤلفون: Mackenzie W. Amoroso, Jianwei Hou, Hynek Wichterle, Christopher E. Henderson, Said M. Sebti, Takaaki Kuwajima, Brent R. Stockwell, Wan Seok Yang, Gist F. Croft, Raghavendra Hosur, Derek H. Oakley, Elena Nikulina, Emily Rhodes Lowry, Nuno Jorge Lamas, Hai Li, Marie T. Filbin
المساهمون: Universidade do Minho
المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cell Reports, Vol 16, Iss 2, Pp 545-558 (2016)مصطلحات موضوعية: 0301 basic medicine, Nervous system, Geranylgeranyl Transferase, Neurite, Farnesyltransferase, Medicina Básica [Ciências Médicas], Protein Prenylation, Mevalonic Acid, Cell Enlargement, Inhibitory postsynaptic potential, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Neurites, medicine, Animals, Humans, Amyotrophic lateral sclerosis, lcsh:QH301-705.5, Cells, Cultured, Motor Neurons, Science & Technology, biology, Regeneration (biology), Amyotrophic Lateral Sclerosis, medicine.disease, Nerve Regeneration, 3. Good health, Cell biology, 030104 developmental biology, medicine.anatomical_structure, lcsh:Biology (General), nervous system, Biochemistry, Ciências Médicas::Medicina Básica, biology.protein, Protein prenylation, Hydroxymethylglutaryl-CoA Reductase Inhibitors, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92cc80d9aaa63bb667ec34e9a4a4d305Test
https://doi.org/10.1016/j.celrep.2016.06.013Test -
4
المؤلفون: Amy M. Danowitz, Benjamin C. Jennings, Yen Chih Wang, Mark D. Distefano, Carol A. Fierke, Richard A. Gibbs
المصدر: Bioorganic & Medicinal Chemistry Letters. 26(4):1333-1336
مصطلحات موضوعية: 0301 basic medicine, Farnesyltransferase, Clinical Biochemistry, Protein Prenylation, Pharmaceutical Science, Biochemistry, Article, Substrate Specificity, 03 medical and health sciences, Polyisoprenyl Phosphates, Prenylation, In vivo, Drug Discovery, Reactivity (chemistry), Molecular Biology, Alkyl and Aryl Transferases, 030102 biochemistry & molecular biology, biology, Chemistry, Organic Chemistry, In vitro, Kinetics, 030104 developmental biology, Alkynes, Click chemistry, biology.protein, Protein farnesylation, Protein prenylation, Molecular Medicine, Click Chemistry, Peptides, Sesquiterpenes
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29dc246930862466328636dee6cb130Test
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5
المؤلفون: Joshua E. Elias, Lichao Zhang, Jolyn E. Gisselberg, Ellen Yeh
المصدر: Molecular & Cellular Proteomics. 16:S54-S64
مصطلحات موضوعية: 0301 basic medicine, biology, Farnesyltransferase, Farnesyl Transferase Inhibitor, 030106 microbiology, Prenyltransferase, Plasmodium falciparum, biology.organism_classification, Biochemistry, Analytical Chemistry, 03 medical and health sciences, 030104 developmental biology, Prenylation, Proteome, biology.protein, Protein prenylation, Rab, Molecular Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::25d835f59a20f232ee9fa254477a6c93Test
https://doi.org/10.1074/mcp.m116.064550Test -
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المؤلفون: Wayne A. Johnston, Marta H. Kubala, Sergey Mureev, Guillermo A. Gomez, Kirill Alexandrov, Alpha S. Yap, Alun Jones, Suzanne J. Norwood
المساهمون: Kubala, Marta H, Norwood, Suzanne J, Gomez, Guillermo A, Jones, Alun, Johnston, Wayne, Yap, Alpha S, Mureev, Sergey, Alexandrov, Kirill
المصدر: Biochemical and Biophysical Research Communications. 468:580-586
مصطلحات موضوعية: Biochemistry & Molecular Biology, isoprenylation, Protein subunit, Farnesyltransferase, Biophysics, Endosomes, Biochemistry, oligomerization, Prenylation, trafficking, Farnesyltranstransferase, Humans, Molecular Biology, Adenosine Triphosphatases, Vacuolar protein sorting, Endosomal Sorting Complexes Required for Transport, biology, HEK 293 cells, Cell Biology, VPS4A, Endocytosis, Transport protein, Cell biology, Protein Subunits, Protein Transport, HEK293 Cells, farnesyltransferase, biology.protein, ATPases Associated with Diverse Cellular Activities, Protein prenylation, Subcellular Fractions
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f8ed5b979f8e11104135758e67d92bTest
https://doi.org/10.1016/j.bbrc.2015.10.148Test -
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المؤلفون: Raymond J. Hohl, Sarah A. Holstein
المصدر: Current Opinion in Pharmacology. 12:704-709
مصطلحات موضوعية: Farnesyltransferase, Prenyltransferase, Protein Prenylation, aptX, Antineoplastic Agents, Pharmacology, Bioinformatics, Prenylation, Neoplasms, Drug Discovery, medicine, Animals, Guanine Nucleotide Exchange Factors, Humans, Enzyme Inhibitors, biology, Nuclear Proteins, Myeloid leukemia, Dimethylallyltranstransferase, medicine.disease, DNA-Binding Proteins, Clinical trial, Leukemia, Myeloid, Acute, Leukemia, Genes, ras, Drug Design, biology.protein, Protein prenylation, Protein Processing, Post-Translational
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83964bd5059ae285e4cf4201d0cbca23Test
https://doi.org/10.1016/j.coph.2012.06.013Test -
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المؤلفون: H. Peter Spielmann, Arnold Ganser, Douglas A. Andres, Christoph W. M. Reuter, Thangaiah Subramanian, Michael A. Morgan, Fredrick O. Onono
المصدر: Molecular & Cellular Proteomics. 9:742-751
مصطلحات موضوعية: Proteomics, Proteome, Geranylgeranyl pyrophosphate, Farnesyltransferase, Blotting, Western, Protein Prenylation, Farnesyl pyrophosphate, HL-60 Cells, Biology, Models, Biological, Biochemistry, Substrate Specificity, Analytical Chemistry, chemistry.chemical_compound, Geranylgeranylation, Prenylation, Cell Line, Tumor, Farnesyltranstransferase, Humans, Electrophoresis, Gel, Two-Dimensional, Enzyme Inhibitors, Molecular Biology, Aniline Compounds, Staining and Labeling, Research, organic chemicals, Imidazoles, chemistry, biology.protein, Protein farnesylation, Protein prenylation, lipids (amino acids, peptides, and proteins), K562 Cells
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::917d6b90284735d27ca8bcf8d957d112Test
https://doi.org/10.1074/mcp.m900597-mcp200Test -
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المؤلفون: Lorena S. Beese, Michael A. Hast
المصدر: Journal of Biological Chemistry. 283:31933-31940
مصطلحات موضوعية: Models, Molecular, Farnesyltransferase, Prenyltransferase, Protein Prenylation, GTPase, Crystallography, X-Ray, Biochemistry, Substrate Specificity, Microbiology, Candida albicans, Humans, Protein Structure, Quaternary, Molecular Biology, Alkyl and Aryl Transferases, Binding Sites, biology, C-terminus, Cell Biology, Protein superfamily, Lipid Metabolism, biology.organism_classification, Corpus albicans, Protein Structure, Tertiary, Protein Structure and Folding, biology.protein, Protein prenylation, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a0896ac0eda61899454c510c8d57a8Test
https://doi.org/10.1074/jbc.m805330200Test -
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المؤلفون: Prakash Rao Pendyala, Ratna Chakrabarti, Melissa Schreiber, Debopam Chakrabarti, Connie Pham, David A. Fidock, Lawrence Ayong, Jennifer Eatrides, Charles M. Allen
المصدر: Molecular and Biochemical Parasitology. 158:1-10
مصطلحات موضوعية: Farnesyltransferase, Molecular Sequence Data, Plasmodium falciparum, Phosphatase, Protein Prenylation, Protozoan Proteins, Antigens, Protozoan, Protein tyrosine phosphatase, Endoplasmic Reticulum, Prenylation, parasitic diseases, Animals, Farnesyltranstransferase, Amino Acid Sequence, Enzyme Inhibitors, Molecular Biology, Sequence Homology, Amino Acid, biology, Gene Expression Profiling, Endoplasmic reticulum, Membrane Proteins, Apical membrane, biology.organism_classification, Cell biology, Protein Transport, Biochemistry, Vacuoles, biology.protein, Protein prenylation, Parasitology, Protein Tyrosine Phosphatases, Oligopeptides
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48997e3beaed99d47ed2adbd3c82f18bTest
https://doi.org/10.1016/j.molbiopara.2007.11.006Test