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1Glycolysis and subsequent mevalonate biosynthesis play an important role in Th2 cell differentiation
المؤلفون: Yasushi Imai, Junpei Suzuki, Makoto Kuwahara, Masakatsu Yamashita, Yuichiro Yagi
المصدر: Biochemical and Biophysical Research Communications. 530:355-361
مصطلحات موضوعية: Male, 0301 basic medicine, Pyruvate dehydrogenase kinase, Cellular differentiation, Farnesyltransferase, Biophysics, Mevalonic Acid, Biochemistry, 03 medical and health sciences, Th2 Cells, 0302 clinical medicine, Animals, Anilides, Glycolysis, Receptor, Protein Kinase Inhibitors, Molecular Biology, Transcription factor, Cells, Cultured, biology, Chemistry, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Cell Differentiation, Cell Biology, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Cytokines, Protein prenylation, Protein farnesylation, Female
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c56cee89268f5ada4e30aa089e3c47Test
https://doi.org/10.1016/j.bbrc.2020.08.009Test -
2
المؤلفون: Lauren V. Procter, Dominic Esposito, Carissa Grose
المصدر: Protein Expression and Purification. 151:99-105
مصطلحات موضوعية: 0301 basic medicine, Insecta, Genetic Vectors, Protein Prenylation, Protein Engineering, medicine.disease_cause, Cell Line, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Geranylgeranylation, Prenylation, Escherichia coli, medicine, Protein biosynthesis, Animals, Humans, Insect cell, Oncogene, Chemistry, Recombinant Proteins, Cell biology, 030104 developmental biology, Protein prenylation, KRAS, Baculoviridae, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e60534c393f61a9cda053a4739f0219Test
https://doi.org/10.1016/j.pep.2018.06.012Test -
3
المؤلفون: Meet Patel, William P. Saunders, Melanie J. Blanden, Walter K. Schmidt, Daniel S. Hardgrove, Kiall F. Suazo, James L. Hougland, Emily R. Hildebrandt, Mark D. Distefano
المصدر: Journal of Biological Chemistry. 293:2770-2785
مصطلحات موضوعية: Models, Molecular, Proteomics, 0301 basic medicine, Saccharomyces cerevisiae Proteins, Recombinant Fusion Proteins, Farnesyltransferase, Amino Acid Motifs, Green Fluorescent Proteins, Protein Prenylation, Saccharomyces cerevisiae, Biochemistry, Substrate Specificity, 03 medical and health sciences, Prenylation, Genes, Reporter, Animals, Humans, Enzyme Inhibitors, Databases, Protein, Molecular Biology, Alkyl and Aryl Transferases, biology, Chemistry, C-terminus, Cell Biology, Rats, Protein Subunits, HEK293 Cells, 030104 developmental biology, Microscopy, Fluorescence, Proteome, Enzymology, Protein geranylgeranyltransferase type I, biology.protein, Protein farnesylation, Protein prenylation, Sequence motif
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ababbda007187fd90bf9ffc2570e8d4aTest
https://doi.org/10.1074/jbc.m117.805770Test -
4
المؤلفون: Emily B. Askew, Cheryl B. Knudson, Nobunori Takahashi, Michelle Cobb, Warren Knudson, Kenya Terabe
المصدر: Archives of Biochemistry and Biophysics. 665:1-11
مصطلحات موضوعية: 0301 basic medicine, Simvastatin, Biophysics, SOX9, Biochemistry, Bone morphogenetic protein 2, Article, Chondrocyte, 03 medical and health sciences, Chondrocytes, Prenylation, polycyclic compounds, medicine, Animals, Humans, cardiovascular diseases, Molecular Biology, Cells, Cultured, Aggrecan, 030102 biochemistry & molecular biology, biology, Chemistry, nutritional and metabolic diseases, Rats, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Proteoglycan, biology.protein, Protein prenylation, Cattle, lipids (amino acids, peptides, and proteins), medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6324bbf3f886ed89b96c8f4a5d880ce1Test
https://doi.org/10.1016/j.abb.2019.01.038Test -
5
المؤلفون: Hasina Banu, Hui Li, Rong Liu, Qin Pan, Liang Ma
المصدر: Biomedicine & Pharmacotherapy. 99:169-175
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Uterine Cervical Neoplasms, Antineoplastic Agents, Mice, SCID, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Downregulation and upregulation, Cell Line, Tumor, medicine, Animals, Humans, Doxorubicin, Protein Methyltransferases, Enzyme Inhibitors, Pharmacology, Cervical cancer, Chemotherapy, business.industry, Cysmethynil, General Medicine, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, Paclitaxel, chemistry, Apoptosis, 030220 oncology & carcinogenesis, ras Proteins, Cancer research, Protein prenylation, Female, business, Signal Transduction, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d347f809c8533237b905c9fa8de6ed0Test
https://doi.org/10.1016/j.biopha.2018.01.048Test -
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المؤلفون: Li-Lian Yuan, Kyle J. LeBlanc, David A. Hottman, Ling Li, Shaowu Cheng, Andrea L. Gram
المصدر: Neuroscience. 373:207-217
مصطلحات موضوعية: Male, 0301 basic medicine, RHOA, Dendritic spine, Dendritic Spines, Mice, Transgenic, digestive system, Article, GTP Phosphohydrolases, Tissue Culture Techniques, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Maze Learning, Neuroinflammation, Spatial Memory, Alkyl and Aryl Transferases, Neuronal Plasticity, biology, Pyramidal Cells, General Neuroscience, Brain, Excitatory Postsynaptic Potentials, Long-term potentiation, digestive system diseases, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Synaptic plasticity, Forebrain, biology.protein, Protein prenylation, Female, Neuron, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4891e6b173362737733cabb877c1e9f4Test
https://doi.org/10.1016/j.neuroscience.2018.01.026Test -
7
المؤلفون: Bin Xue, Chao-Jun Li, Wen-Jun Jia, Di Shen, Yue Zhao, Yudong Qiu, Shan Jiang, Qiao-Li Tang
المصدر: European Journal of Pharmacology. 814:169-177
مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Zoledronic Acid, Mice, 03 medical and health sciences, Farnesyl diphosphate synthase, Non-alcoholic Fatty Liver Disease, Internal medicine, medicine, Animals, Humans, Pharmacology, Liver injury, Diphosphonates, biology, Chemistry, Lipogenesis, Fatty liver, Imidazoles, Geranyltranstransferase, Lipid metabolism, medicine.disease, Enzyme Activation, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Liver, biology.protein, Protein prenylation, lipids (amino acids, peptides, and proteins), Mevalonate pathway, Steatosis, rhoA GTP-Binding Protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27d01741f31df1bbb1a1a11cf56f9f9Test
https://doi.org/10.1016/j.ejphar.2017.08.010Test -
8
المؤلفون: Hongyan Cui, Akiko Hachisuka, Keisuke Soga, Akihiko Hirose, Kazunari Kondo, Reiko Adachi, Norimasa Tamehiro, Tomoko Nishimaki-Mogami
المصدر: Biochemical Pharmacology. 188:114580
مصطلحات موضوعية: 0301 basic medicine, Statin, Geranylgeranyl pyrophosphate, THP-1 Cells, medicine.drug_class, Atorvastatin, Interleukin-1beta, Farnesyl pyrophosphate, Pharmacology, Biochemistry, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Animals, Humans, Pitavastatin, Mice, Inbred BALB C, Nanotubes, Carbon, Cholesterol, Macrophages, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Protein prenylation, Female, lipids (amino acids, peptides, and proteins), Lovastatin, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Crystallization, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de78a9bbcd729e5d8239b586d8821d4fTest
https://doi.org/10.1016/j.bcp.2021.114580Test -
9
المؤلفون: Mackenzie W. Amoroso, Jianwei Hou, Hynek Wichterle, Christopher E. Henderson, Said M. Sebti, Takaaki Kuwajima, Brent R. Stockwell, Wan Seok Yang, Gist F. Croft, Raghavendra Hosur, Derek H. Oakley, Elena Nikulina, Emily Rhodes Lowry, Nuno Jorge Lamas, Hai Li, Marie T. Filbin
المساهمون: Universidade do Minho
المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cell Reports, Vol 16, Iss 2, Pp 545-558 (2016)مصطلحات موضوعية: 0301 basic medicine, Nervous system, Geranylgeranyl Transferase, Neurite, Farnesyltransferase, Medicina Básica [Ciências Médicas], Protein Prenylation, Mevalonic Acid, Cell Enlargement, Inhibitory postsynaptic potential, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Neurites, medicine, Animals, Humans, Amyotrophic lateral sclerosis, lcsh:QH301-705.5, Cells, Cultured, Motor Neurons, Science & Technology, biology, Regeneration (biology), Amyotrophic Lateral Sclerosis, medicine.disease, Nerve Regeneration, 3. Good health, Cell biology, 030104 developmental biology, medicine.anatomical_structure, lcsh:Biology (General), nervous system, Biochemistry, Ciências Médicas::Medicina Básica, biology.protein, Protein prenylation, Hydroxymethylglutaryl-CoA Reductase Inhibitors, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92cc80d9aaa63bb667ec34e9a4a4d305Test
https://doi.org/10.1016/j.celrep.2016.06.013Test -
10
المؤلفون: Ruslan Medzhitov, Daniel Okin
المصدر: Cell. 165:343-356
مصطلحات موضوعية: Blood Glucose, Lipopolysaccharides, 0301 basic medicine, medicine.medical_specialty, Transcription, Genetic, Protein Prenylation, RhoC, Mevalonic Acid, Mice, Obese, Inflammation, Type 2 diabetes, General Biochemistry, Genetics and Molecular Biology, Hepatitis, Proinflammatory cytokine, Mice, 03 medical and health sciences, Internal medicine, medicine, Animals, Glucose homeostasis, Cholesterol 7-alpha-Hydroxylase, Triglycerides, rho-Associated Kinases, biology, Fasting, medicine.disease, Biosynthetic Pathways, 030104 developmental biology, Endocrinology, rhoC GTP-Binding Protein, Hyperglycemia, ras Proteins, biology.protein, Protein prenylation, Mevalonate pathway, Chemical and Drug Induced Liver Injury, medicine.symptom, RhoC GTP-Binding Protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4cf782d8298164f579574f4c7606715Test
https://doi.org/10.1016/j.cell.2016.02.023Test