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المؤلفون: Brian S. J. Blagg, Michael A. Serwetnyk
المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1446-1468 (2021)مصطلحات موضوعية: MD, middle domain, Review, SUMO, small ubiquitin-like modifier, TPR2A, tetratricopeptide-containing repeat 2A, chemistry.chemical_compound, 0302 clinical medicine, Immunophilins, polycyclic compounds, General Pharmacology, Toxicology and Pharmaceutics, Natural products, 0303 health sciences, biology, Small molecules, HIF-1α, hypoxia-inducing factor-1α, HSQC, heteronuclear single quantum coherence, Geldanamycin, Hsp90, CTD, C-terminal domain, Radicicol, Cell biology, 030220 oncology & carcinogenesis, HOP, Hsp70‒Hsp90 organizing protein, SAHA, suberoylanilide hydroxamic acid, Protein folding, ATP, adenosine triphosphate, Cdc37, cell division cycle 37, RM1-950, Protein–protein interaction, 03 medical and health sciences, TROSY, transverse relaxation-optimized spectroscopy, Heat shock protein, SAR, structure–activity relationship, NTD, N-terminal domain, Heat shock, 030304 developmental biology, Disruptors, TRAP1, Hsp75tumor necrosis factor receptor associated protein 1, Hsp90, 90-kD heat shock protein, Her-2, human epidermal growth factor receptor-2, Aha1, activator of Hsp90 ATPase homologue 1, HIP, Hsp70-interaction protein, hERG, human ether-à-go-go-related gene, PPI, protein−protein interaction, ADP, adenosine diphosphate, chemistry, Grp94, 94-kD glucose-regulated protein, biology.protein, Protein−protein interactions, Therapeutics. Pharmacology, Peptidomimetics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d551031a93c74226093f0f0844e22506Test
https://doi.org/10.1016Test/j .apsb.2020.11.015 -
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المؤلفون: Brian S. J. Blagg, Mark S. Cohen, Derek Ge, Chitra Subramanian, Nina Zhang, Rebecca Gorney, Ton Wang, Ang Zuo
المصدر: Surgery
مصطلحات موضوعية: Aminocoumarins, Antineoplastic Agents, 030230 surgery, Heat Shock Protein Inhibitor, Article, Inhibitory Concentration 50, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Western blot, Cell Line, Tumor, Heat shock protein, Adenocarcinoma, Follicular, medicine, Humans, Glycolysis, HSP90 Heat-Shock Proteins, Thyroid Neoplasms, medicine.diagnostic_test, business.industry, Phenylurea Compounds, Cell biology, Metabolic pathway, Real-time polymerase chain reaction, chemistry, Drug Resistance, Neoplasm, Thyroid Epithelial Cells, 030220 oncology & carcinogenesis, Quinolines, Surgery, Drug Screening Assays, Antitumor, Lenvatinib, business, Pyruvate kinase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d760782125c29dca019d237afaa2b438Test
https://doi.org/10.1016Test/j .surg.2020.06.009 -
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المؤلفون: Mark S. Cohen, Chitra Subramanian, Brian S. J. Blagg, Ton Wang
المصدر: Surgery. 167:233-240
مصطلحات موضوعية: Cell Survival, Cellular homeostasis, Antineoplastic Agents, Apoptosis, 030230 surgery, Hsp90 inhibitor, Inhibitory Concentration 50, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Cell Movement, Cell Line, Tumor, Adrenocortical Carcinoma, medicine, Humans, Adrenocortical carcinoma, HSP90 Heat-Shock Proteins, Viability assay, Cell Proliferation, business.industry, RNA, medicine.disease, Adrenal Cortex Neoplasms, Long non-coding RNA, Up-Regulation, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Cancer research, RNA, Long Noncoding, Surgery, Drug Screening Assays, Antitumor, GAS5, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e2e32010bf6ff7ba6116aaaba2a8c7Test
https://doi.org/10.1016Test/j .surg.2019.06.052 -
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المؤلفون: M.W. Sim, K.J. Kovatch, Mark E. Prince, Brian S. J. Blagg, Mark S. Cohen, Chitra Subramanian, R. Davis, Thomas E. Carey, Grace M. Wang
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 12, Pp 1003-1011 (2017)
Neoplasia (New York, N.Y.)مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Pathology, BMI1, B lymphoma Mo-MLV insertion region 1 homolog, EMT, epithelial to mesenchymal transition, Vimentin, HNSCC, head and neck squamous cell carcinoma, SCC, squamous cell carcinoma, Mice, 0302 clinical medicine, Tumor Cells, Cultured, Cell Self Renewal, HSP, heat shock protein (Hsp90, Hsp70), lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, 3. Good health, Gene Expression Regulation, Neoplastic, WB, Western blot, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, Neoplastic Stem Cells, Signal Transduction, Original article, medicine.medical_specialty, KU, Kansas University (compounds KU757, KU711), Cell Survival, Antineoplastic Agents, Biology, lcsh:RC254-282, 03 medical and health sciences, Cancer stem cell, Cell Line, Tumor, medicine, Animals, Humans, Protein Interaction Domains and Motifs, HSP90 Heat-Shock Proteins, Epithelial–mesenchymal transition, Squamous Cell Carcinoma of Head and Neck, Mesenchymal stem cell, CD44, medicine.disease, Xenograft Model Antitumor Assays, CSC, cancer stem cell, Head and neck squamous-cell carcinoma, Disease Models, Animal, MicroRNAs, ALDH, aldehyde dehydrogenase, 030104 developmental biology, Drug Resistance, Neoplasm, BMI1, Cell culture, Cancer research, biology.protein, UMSCC, University of Michigan Squamous Cell Carcinoma (cell lines UMSCC 22, UMSCC 22B-cis), Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c7acd843e614f5b59079b1412b9eeeTest
https://doi.org/10.1016Test/j .neo.2017.09.003 -
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المصدر: Bioorganic & Medicinal Chemistry Letters. 27:4514-4519
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Ring (chemistry), Biochemistry, Neuroprotection, Article, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Prostate cancer, 0302 clinical medicine, Cell Line, Tumor, Heat shock protein, Drug Discovery, medicine, Humans, HSP90 Heat-Shock Proteins, Benzamide, Molecular Biology, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, biology, Biphenyl Compounds, Organic Chemistry, Cancer, medicine.disease, Hsp90, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Drug Screening Assays, Antitumor, Acetamide
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6a1229accc852bc09fb475146a96f2Test
https://doi.org/10.1016Test/j .bmcl.2017.07.030 -
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المؤلفون: A.L. Heck, Wulf Schneider-Brachert, Sanket J. Mishra, Vinzenz Särchen, E. Achhammer, L. Feulner, Jürgen Fritsch, Brian S. J. Blagg, T. Prenzel, Stefan Schütze
المصدر: Immunobiology. 226:152070
مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Proteome, Endosome, Immunology, 610 Medizin, Cathepsin D, Apoptosis, TNF-Related Apoptosis-Inducing Ligand, 03 medical and health sciences, 0302 clinical medicine, Humans, Immunology and Allergy, HSP90 Heat-Shock Proteins, ddc:610, biology, Tumor Necrosis Factor-alpha, Chemistry, U937 Cells, Hematology, Hypoxia-Inducible Factor 1, alpha Subunit, Hsp90, Cell biology, 030104 developmental biology, Cytoplasm, biology.protein, Tumor necrosis factor alpha, Intracellular, HeLa Cells, 030215 immunology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf35de9dcff9f09e256d7de2f1d5ed7dTest
https://doi.org/10.1016Test/j .imbio.2021.152070 -
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المؤلفون: Sam V. Kaplan, Gaurav Garg, Shea M. Lemley, Michael A. Johnson, Michael J. Sofis, Rachel C. Gehringer, Brian S. J. Blagg, David P. Jarmolowicz
المصدر: Behavioural Brain Research. 329:186-190
مصطلحات موضوعية: medicine.medical_specialty, Time Factors, medicine.medical_treatment, Hippocampal formation, Audiology, Article, Developmental psychology, 03 medical and health sciences, Behavioral Neuroscience, Myelin, 0302 clinical medicine, medicine, Animals, Rats, Wistar, Set (psychology), Saline, Analysis of Variance, Chemotherapy, Cognition, Rats, Disease Models, Animal, Neuroprotective Agents, medicine.anatomical_structure, Fluorouracil, 030220 oncology & carcinogenesis, Animal studies, Cognition Disorders, Psychology, Immunosuppressive Agents, Novobiocin, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4138972f63982dae52f920c8ed3c457Test
https://doi.org/10.1016Test/j .bbr.2017.03.042 -
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المؤلفون: Mark S. Cohen, Qing Zhu, Barbara N. Timmermann, Chitra Subramanian, Peter T. White, Robert J. Gallagher, Brian S. J. Blagg, Huaping Zhang, Huiping Zhao
المصدر: Surgery. 159:142-151
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Thyroid Gland, 03 medical and health sciences, 0302 clinical medicine, Western blot, Cell Movement, Cell Line, Tumor, Internal medicine, medicine, Anticarcinogenic Agents, Humans, Neoplasm Invasiveness, HSP90 Heat-Shock Proteins, Thyroid Neoplasms, Protein kinase B, Thyroid cancer, Cell Proliferation, biology, medicine.diagnostic_test, Cell growth, CD44, Thyroid, Cell migration, medicine.disease, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, biology.protein, Cancer research, Surgery, Stem cell
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697b350852499ba66ae63c62d41f7bc6Test
https://doi.org/10.1016Test/j .surg.2015.07.050