نتائج البحث - "Glucagon-Like Peptide-1 Receptor"

1

Glucagon-Like Peptide-1 Receptor Agonism Improves Nephrotoxic Serum Nephritis by Inhibiting T-Cell Proliferation

المؤلفون: Foteini Moschovaki Filippidou, Alexander R. Rosenkranz, Alexander H. Kirsch, Akos Heinemann, Kathrin Eller, Corinna Schabhüttl, Thomas R. Pieber, Daniel J. Drucker, Máté Kétszeri, Andreas Meinitzer, Philipp Eller, Tobias Niedrist, Marion J. Pollheimer, Agnes A. Mooslechner, Katharina Artinger, Ida Aringer, Matthias Thelen, Bianca Frauscher

المصدر: The American Journal of Pathology. 190:400-411

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9043816c6c717b6649b7ff5df5fa461fTest
https://doi.org/10.1016/j.ajpath.2019.10.008Test

2

Mono-PEGylates of exenatide in branched and dimeric structures can improve in vivo stability and hypoglycemic bioactivity

المؤلفون: Eun-Yong Lee, Su Jin Jung, Ngoc-Thanh Thi Nguyen, Ok-Nam Bae, Seung Hwan Lee

المصدر: Journal of Biotechnology. 306:89-96

مصطلحات موضوعية: Blood Glucose, 0106 biological sciences, 0301 basic medicine, Agonist, medicine.drug_class, Stereochemistry, Mice, Nude, Mice, Obese, Bioengineering, CHO Cells, Conjugated system, 01 natural sciences, Applied Microbiology and Biotechnology, Glucagon-Like Peptide-1 Receptor, Polyethylene Glycols, Maleimides, Mice, 03 medical and health sciences, Cricetulus, In vivo, 010608 biotechnology, PEG ratio, Cyclic AMP, medicine, Animals, Hypoglycemic Agents, Amino Acid Sequence, chemistry.chemical_classification, Molecular mass, Chemistry, General Medicine, In vitro, Amino acid, Molecular Weight, Disease Models, Animal, 030104 developmental biology, Diabetes Mellitus, Type 2, Exenatide, Half-Life, Biotechnology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d3ebff56321b48372ec018ce320cc7Test
https://doi.org/10.1016/j.jbiotec.2019.09.016Test

3

The novel GLP-1/GIP dual receptor agonist DA3-CH is neuroprotective in the pilocarpine-induced epileptogenesis rat model

المؤلفون: Guo-Fang Xue, Dongfang Li, Miao-Jing Tian, Ru-Lin Mi, Zhen-Yu Yuan, Rui-Fang Wang, Christian Hölscher

المصدر: Epilepsy Research. 154:97-106

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c533584193b5934c85f0098afd6c53Test
https://doi.org/10.1016/j.eplepsyres.2019.05.008Test

4

Dulaglutide ameliorates STZ induced AD-like impairment of learning and memory ability by modulating hyperphosphorylation of tau and NFs through GSK3β

المؤلفون: Yanqiu Deng, Peng Peng, Zhongya Gu, Gang Zhao, Shuyi Chen, Mei Zhou, Jing Yu

المصدر: Biochemical and Biophysical Research Communications. 511:154-160

مصطلحات موضوعية: Male, 0301 basic medicine, Agonist, medicine.medical_specialty, medicine.drug_class, Recombinant Fusion Proteins, Glucagon-Like Peptides, Intermediate Filaments, Biophysics, Hyperphosphorylation, Morris water navigation task, tau Proteins, Biochemistry, Glucagon-Like Peptide-1 Receptor, Streptozocin, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, Memory, Internal medicine, medicine, Animals, Hypoglycemic Agents, Memory impairment, Phosphorylation, Maze Learning, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Memory Disorders, Glycogen Synthase Kinase 3 beta, biology, business.industry, Cell Biology, Immunoglobulin Fc Fragments, Mice, Inbred C57BL, Insulin receptor, 030104 developmental biology, Endocrinology, 030220 oncology & carcinogenesis, biology.protein, Dulaglutide, business, Signal Transduction, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d1346a6a3ba632ac556437a2839d1eTest
https://doi.org/10.1016/j.bbrc.2019.01.103Test

5

Evidence of metabolic memory-induced neurodegeneration and the therapeutic effects of glucagon-like peptide-1 receptor agonists via Forkhead box class O

المؤلفون: Su-Ting Chen, Song Chen, Yan Sun, Ying Wang, Qian Tang, Zheng Xu, Xiangdong Gao, Wenbing Yao

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1865:371-377

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, Agonist, endocrine system, medicine.drug_class, tau Proteins, FOXO1, Pharmacology, Models, Biological, PC12 Cells, Glucagon-Like Peptide-1 Receptor, 03 medical and health sciences, 0302 clinical medicine, Sirtuin 1, Memory, In vivo, Glycation, Diabetes mellitus, Diabetes Mellitus, medicine, Animals, Molecular Biology, Neurons, Amyloid beta-Peptides, Forkhead Box Protein O1, business.industry, digestive, oral, and skin physiology, Neurodegeneration, Neurotoxicity, Acetylation, medicine.disease, Rats, Metformin, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Nerve Degeneration, Molecular Medicine, business, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebaec3ed64c8b24ffd457ec827eb8d60Test
https://doi.org/10.1016/j.bbadis.2018.11.012Test

6

Inhibition of DPP4 enhances inhibitory synaptic transmission through activating the GLP-1/GLP-1R signaling pathway in a rat model of febrile seizures

المؤلفون: Biwen Peng, Fang Yu, Yusong Zhang, Yunli Liu, Zheman Xiao, Song Han, Jun Yin, Xiaohua He, Jian Xu, Wanhong Liu, Jia Cheng, Qi Sun

المصدر: Biochemical Pharmacology. 156:78-85

مصطلحات موضوعية: Male, 0301 basic medicine, endocrine system, Dipeptidyl Peptidase 4, Pharmacology, Neurotransmission, Inhibitory postsynaptic potential, Hippocampus, Biochemistry, Glucagon-Like Peptide-1 Receptor, Seizures, Febrile, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Glucagon-Like Peptide 1, In vivo, medicine, Animals, Receptor, Dipeptidyl-Peptidase IV Inhibitors, Gene knockdown, Chemistry, Neurturin, Sitagliptin Phosphate, digestive, oral, and skin physiology, Rats, 030104 developmental biology, Gene Expression Regulation, Sitagliptin, Female, RNA Interference, Signal transduction, 030217 neurology & neurosurgery, Signal Transduction, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7619b0a4ce1294c627155ca93bd1009bTest
https://doi.org/10.1016/j.bcp.2018.08.004Test

7

Sitagliptin attenuates intestinal ischemia/reperfusion injury via cAMP/PKA, PI3K/Akt pathway in a glucagon-like peptide 1 receptor-dependent manner

المؤلفون: Rehab M. Khedr, Rehab Kamel, Amany A.E. Ahmed, Eman M. Raafat

المصدر: Life Sciences. 211:31-39

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Apoptosis, Glucagon-Like Peptide-1 Receptor, General Biochemistry, Genetics and Molecular Biology, Rats, Sprague-Dawley, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, 0302 clinical medicine, Glucagon-Like Peptide 1, Internal medicine, Cyclic AMP, medicine, Animals, Hypoglycemic Agents, Intestinal Mucosa, General Pharmacology, Toxicology and Pharmaceutics, Receptor, Protein kinase B, Glucagon-like peptide 1 receptor, PI3K/AKT/mTOR pathway, Inflammation, Akt/PKB signaling pathway, Chemistry, Sitagliptin Phosphate, General Medicine, medicine.disease, Cyclic AMP-Dependent Protein Kinases, Glucagon-like peptide-1, Rats, Intestines, Intestinal Diseases, 030104 developmental biology, Endocrinology, Gene Expression Regulation, Reperfusion Injury, 030220 oncology & carcinogenesis, Sitagliptin, Inflammation Mediators, Proto-Oncogene Proteins c-akt, Reperfusion injury, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ad04e8b54d4809f17ef649701b8589Test
https://doi.org/10.1016/j.lfs.2018.09.013Test

8

The effect of glucagon-like peptide 1 and glucagon-like peptide 1 receptor agonists on energy expenditure: A systematic review and meta-analysis

المؤلفون: Angélica Amorim Amato, Fernanda Cerqueira Barroso de Oliveira, Michella Soares Coelho, Francisco de Assis Rocha Neves, Michel Garcia Maciel, Carolina Martins Ribeiro, Bruna Teles Soares Beserra

المصدر: Diabetes Research and Clinical Practice. 142:222-235

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, endocrine system, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Glucagon-Like Peptide-1 Receptor, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Glucagon-Like Peptide 1, Weight loss, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, Hypoglycemic Agents, business.industry, Liraglutide, digestive, oral, and skin physiology, General Medicine, medicine.disease, Glucagon-like peptide-1, Clinical trial, 030104 developmental biology, Diabetes Mellitus, Type 2, Meta-analysis, Female, medicine.symptom, Energy Metabolism, business, Exenatide, Thermogenesis, hormones, hormone substitutes, and hormone antagonists, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2254da4de7293f2284552ae6c70d6ddeTest
https://doi.org/10.1016/j.diabres.2018.05.034Test

9

GLP-1 receptor agonists stimulate ANGPTL8 production through the PI3K/Akt pathway in a GLP-1 receptor-dependent manner

المؤلفون: Jin Yang, Tianpei Hong, Rui Wei, Junling Liu, Jingjing Zhang, Shan Lang, Kun Yang, Wenhua Xiao, Yunyi Le

المصدر: Peptides. 106:83-90

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Agonist, China, medicine.medical_specialty, endocrine system diseases, Physiology, medicine.drug_class, Peptide Hormones, Type 2 diabetes, Biochemistry, Glucagon-Like Peptide-1 Receptor, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, Cellular and Molecular Neuroscience, Endocrinology, Angiopoietin-Like Protein 8, Internal medicine, medicine, Humans, Hypoglycemic Agents, Receptor, Glucagon-like peptide 1 receptor, Aged, Liraglutide, business.industry, Antagonist, nutritional and metabolic diseases, Hep G2 Cells, Middle Aged, medicine.disease, Glucagon-like peptide-1, Angiopoietin-like Proteins, 030104 developmental biology, Diabetes Mellitus, Type 2, Hepatocytes, Exenatide, Female, business, Proto-Oncogene Proteins c-akt, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba81529094f6a6707e97b25e3e1c8c5Test
https://doi.org/10.1016/j.peptides.2018.07.001Test

10

PPG neurons in the nucleus of the solitary tract modulate heart rate but do not mediate GLP-1 receptor agonist-induced tachycardia in mice

المؤلفون: James E. Richards, Daniel R. Cook, Daniel I. Brierley, Stefan Trapp, Nephtali Marina, Alexander V. Gourine, Marie K. Holt, Frank Reimann

المساهمون: Reimann, Frank [0000-0001-9399-6377], Apollo - University of Cambridge Repository

المصدر: Molecular Metabolism, Vol 39, Iss, Pp 101024-(2020)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Tachycardia, medicine.medical_specialty, lcsh:Internal medicine, Sympathetic Nervous System, 030209 endocrinology & metabolism, Mice, Transgenic, Proglucagon, Glucagon-Like Peptide-1 Receptor, 03 medical and health sciences, Electrocardiography, Mice, 0302 clinical medicine, Heart Rate, Internal medicine, medicine, Solitary Nucleus, Premovement neuronal activity, Animals, Sympathetic outflow, Receptor, lcsh:RC31-1245, Molecular Biology, Biotelemetry, Neurons, business.industry, Solitary tract, Muscarinic antagonist, Cell Biology, Spinal cord, Cardiovascular function, Atropine, PPG neurons, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, nervous system, Spinal Cord, Exenatide, Original Article, Neuron, Chemogenetics, medicine.symptom, business, GLP-1, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8195ac1949a952787e48c886f1fe08b1Test

تنقيح النتائج