يعرض 1 - 8 نتائج من 8 نتيجة بحث عن '"Poller Birk"', وقت الاستعلام: 0.90s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Examining P-gp efflux kinetics guided by the BDDCS – Rational selection of in vitro assay designs and mathematical models

    المؤلفون: Riede, Julia, Umehara, Ken-Ichi, Schweigler, Patrick, Huth, Felix, Schiller, Hilmar, Camenisch, Gian P., Poller, Birk

    العلاقة: Riede, Julia, Umehara, Ken-Ichi, Schweigler, Patrick, Huth, Felix, Schiller, Hilmar, Camenisch, Gian P. and Poller, Birk (2019) Examining P-gp efflux kinetics guided by the BDDCS – Rational selection of in vitro assay designs and mathematical models. European Journal of Pharmaceutical Sciences, 132. pp. 132-141. ISSN 18790720

    الإتاحة: https://doi.org/10.1016/j.ejps.2019.03.005Test
    https://oak.novartis.com/38363Test/

    View record in BASE

    أضف إلى المفضلة
  2. 2
    دورية أكاديمية
    Novel insights into bile acid detoxification via CYP, UGT and SULT enzymes.

    المؤلفون: Kastrinou Lampou, Vlasia1,2,3 (AUTHOR), Poller, Birk1 (AUTHOR), Huth, Felix1 (AUTHOR), Fischer, Audrey2 (AUTHOR), Kullak-Ublick, Gerd A.3,4 (AUTHOR), Arand, Michael5 (AUTHOR), Schadt, Heiko S.2 (AUTHOR), Camenisch, Gian1 (AUTHOR) gian.camenisch@novartis.com

    المصدر: Toxicology in Vitro. Mar2023, Vol. 87, pN.PAG-N.PAG. 1p.

    مصطلحات موضوعية: *BILE acids, *ENZYMES, *METABOLIC detoxification, *HOMEOSTASIS, *LIVER microsomes, *SULFATION, *CYTOCHROME P-450 CYP3A


    أضف إلى المفضلة
  3. 3
    دورية أكاديمية
    New IVIVE method for the prediction of total human clearance and relative elimination pathway contributions from in vitro hepatocyte and microsome data.

    المؤلفون: Riede, Julia1,2, Poller, Birk1, Umehara, Ken-ichi1, Huwyler, Jörg2, Camenisch, Gian1 gian.camenisch@novartis.com

    المصدر: European Journal of Pharmaceutical Sciences. Apr2016, Vol. 86, p96-102. 7p.

    مصطلحات موضوعية: *LIVER cells, *PHARMACOKINETICS, *MICROSOMES, *DRUG side effects, *DATA analysis


    أضف إلى المفضلة
  4. 4
    دورية أكاديمية
    Predicting Oral Absorption for Compounds Outside the Rule of Five Property Space.

    المؤلفون: Huth, Felix1 (AUTHOR) felix.huth@novartis.com, Domange, Norbert1 (AUTHOR), Poller, Birk1 (AUTHOR), Vapurcuyan, Arpine2 (AUTHOR), Durrwell, Alexandre1 (AUTHOR), Hanna, Imad D.3 (AUTHOR), Faller, Bernard1 (AUTHOR)

    المصدر: Journal of Pharmaceutical Sciences. Jun2021, Vol. 110 Issue 6, p2562-2569. 8p.

    مصطلحات موضوعية: *MOLECULAR weights, *ABSORPTION, *DRUG absorption, *PHARMACEUTICAL chemistry, *PERMEABILITY


    أضف إلى المفضلة
  5. 5
    دورية أكاديمية
    In Vitro- In Vivo Extrapolation Method to Predict Human Renal Clearance of Drugs.

    المؤلفون: Kunze, Annett1,2, Huwyler, Jörg2, Poller, Birk1, Gutmann, Heike1, Camenisch, Gian1

    المصدر: Journal of Pharmaceutical Sciences. Mar2014, Vol. 103 Issue 3, p994-1001. 8p. 3 Charts, 2 Graphs.

    مصطلحات موضوعية: *EXTRAPOLATION, *KIDNEY physiology, *GLOMERULAR filtration rate, *BIOPHARMACEUTICS, *DRUG absorption, *IN vitro studies


    أضف إلى المفضلة
  6. 6
    دورية أكاديمية
    In vitro P-glycoprotein efflux inhibition by atypical antipsychotics is in vivo nicely reflected by pharmacodynamic but less by pharmacokinetic changes

    المؤلفون: Schmitt, Ulrich1 schmitt@psychiatrie.klinik.uni-mainz.de, Kirschbaum, Katrin M.1, Poller, Birk2, Kusch-Poddar, Manisha2, Drewe, Jürgen2, Hiemke, Christoph1, Gutmann, Heike2

    المصدر: Pharmacology, Biochemistry & Behavior. Aug2012, Vol. 102 Issue 2, p312-320. 9p.

    مصطلحات موضوعية: *GLYCOPROTEINS, *ANTIPSYCHOTIC agents, *PHARMACODYNAMICS, *PHARMACOKINETICS, *BLOOD-brain barrier, *RHODAMINES, *STATISTICAL correlation


    أضف إلى المفضلة
  7. 7
    دورية أكاديمية
    Current In Vitro Methods to Determine Hepatic Kpuu: A Comparison of Their Usefulness and Limitations.

    المؤلفون: Riede, Julia1,2, Camenisch, Gian1, Huwyler, Jörg2, Poller, Birk1 birk.poller@novartis.com

    المصدر: Journal of Pharmaceutical Sciences. Sep2017, Vol. 106 Issue 9, p2805-2814. 10p.

    مصطلحات موضوعية: *DRUG interactions, *PHARMACOKINETICS, *LIVER cells, *HEMODIALYSIS, *DRUG toxicity


    أضف إلى المفضلة
  8. 8
    دورية أكاديمية
    Cytokine signaling in the human brain capillary endothelial cell line hCMEC/D3

    المؤلفون: Fasler-Kan, Elizaveta1, Suenderhauf, Claudia2, Barteneva, Natasha3, Poller, Birk4, Gygax, Daniel1, Huwyler, Jörg2,4 joerg.huwyler@unibas.ch

    المصدر: Brain Research. Oct2010, Vol. 1354, p15-22. 8p.

    مصطلحات موضوعية: *CYTOKINES, *CELLULAR signal transduction, *CELL lines, *BLOOD-brain barrier, *BRAIN blood-vessels, *INFLAMMATION, *MAJOR histocompatibility complex, *NF-kappa B


    أضف إلى المفضلة
أدوات البحث: أحصل على تغذية RSS — أرسل هذا البحث بالبريد الإلكتروني — حفظ البحث