التفاصيل البيبلوغرافية
| العنوان: |
Effect of acupuncture on electroencephalographic responses to noxious stimuli in halothane-anesthetized dogs. |
| المؤلفون: |
Moriyasu, Sa1, Greene, Sa2, Moore, Mp1 |
| المصدر: |
Veterinary Anaesthesia & Analgesia. Apr2001, Vol. 28 Issue 2, p100-100. 0p. |
| مصطلحات موضوعية: |
*VETERINARY electroencephalography, *ACUPUNCTURE anesthesia |
| مستخلص: |
Quantitative electroencephalography (QEEG) of anesthetized dogs has been used to humanely measure morphine's attenuation of CNS responses to noxious stimuli (STIM). The purpose of this study was to similarly determine the effect of acupuncture on responses to STIM as characterized by changes in QEEG. Six mixed-breed dogs were studied; mean ± SD weight and age of 32.8 ± 7.3 kg and 5 ± 0.8 years, respectively. Dogs were mask-induced with halothane (HAL) in oxygen and maintained at 1.7% end-tidal HAL concentration with controlled ventilation. Three treatments, each with and without electrical STIM, were studied in the following order: HAL alone, HAL with low frequency (1.4 Hz) electroacupuncture (LFA), and HAL with high frequency (150 Hz) electroacupuncture (HFA). Alternating current electroacupuncture was performed using needles placed in two acupuncture points on each pelvic limb (Stomach 36 and Spleen 6). Ten minutes of QEEG was collected using a Neurometric Analyzer both prior to and 2 minutes after STIM. STIM was twice the electric current needed to elicit a maximal amplitude compound motor unit action potential (10 second-1 for 15 seconds) using a constant-voltage stimulator applied proximal to the tarsus. Absolute power of the EEG was analyzed by repeated measures anova on ranks followed by the Student-Newman-Keuls' test when indicated by significant F-values (p < 0.05). STIM in HAL-anesthetized dogs was associated with significant decreases in δ and α frequencies of the EEG at 14 of 21 electrode sites. During LFA, significant decreases in δ alone were observed at only four of 21 sites following STIM. During HFA, significant decreases in δ, α, and β frequencies were observed at only six of 21 sites following STIM. Heart rate, arterial blood pressure, and end-tidal CO2 tension were unchanged throughout the study. We conclude that both LFA and HFA attenuate the QEEG response to STIM during 1.7% HAL anesthesia suggesting electroacupuncture-induced alteration in CNS pain processing. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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