التفاصيل البيبلوغرافية
| العنوان: |
Euglycemic Diabetic Ketoacidosis Secondary to Dapagliflozin Use: A Case Report. |
| المؤلفون: |
Brown, Felicity1, McColl, Tamara1 |
| المصدر: |
Journal of Emergency Medicine (0736-4679). Jan2018, Vol. 54 Issue 1, p109-111. 3p. |
| مصطلحات موضوعية: |
*DIABETIC acidosis, *DAPAGLIFLOZIN, *GLYCEMIC index, *EMERGENCY physicians, *SODIUM-glucose cotransporters, *DIAGNOSIS, *THERAPEUTICS |
| مستخلص: |
Background: Sodium-glucose co-transporter-2 (SGLT2) inhibitors are a novel class of oral antihyperglycemic agents. They are associated with rare cases of euglycemic diabetic ketoacidosis (DKA), which presents a diagnostic challenge in the emergency department (ED) and potentially severe consequences if missed.Case Report: A 53-year-old man with type 2 diabetes mellitus and a recent Roux-en-Y gastric bypass surgery presented to the ED with nausea, vomiting, and generalized abdominal pain. His medications included dapagliflozin. Work-up revealed anion-gap acidosis, which prompted us to send serum ketone levels despite a blood glucose level of 9.8 mmol/L (162 mg/dL). The patient was ultimately diagnosed with euglycemic DKA. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Patients on SGLT2 inhibitors may present in DKA despite having normal blood glucose levels. It is important for emergency physicians to be aware of this phenomenon in all SGLT2-inhibitor users, as a delay in the diagnosis of DKA can be life threatening. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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