التفاصيل البيبلوغرافية
| العنوان: |
Benefit of implantable cardioverter-defibrillator therapy after generator replacement in patients with Brugada syndrome. |
| المؤلفون: |
Ju Youn Kim1, Sung-Hwan Kim1, Sung Su Kim2, Ki Hong Lee2, Hyung-Wook Park2, Jeong-Gwan Cho2, Jae-Sun Uhm3, Boyoung Joung3, Hui-Nam Pak3, Moon-Hyoung Lee3, Seung-Jung Park4, Young Keun On4, June Soo Kim4, Hong Euy Lim5, Jaemin Shim6, Jong-Il Choi6, Sang Weon Park6, Young-Hoon Kim6, Woo Seok Lee7, Jun Kim7 |
| المصدر: |
International Journal of Cardiology. May2015, Vol. 187, p340-344. 5p. |
| مصطلحات موضوعية: |
*ARTIFICIAL implants, *BRUGADA syndrome, *IMPLANTABLE cardioverter-defibrillators, *RETROSPECTIVE studies, *MEDICAL centers, *PATIENTS |
| مستخلص: |
Background An implantable cardioverter-defibrillator (ICD) is the only proven effective therapeutic strategy for patients with Brugada syndrome (BS). However, it is controversial whether the device should be replaced even in patients who had never experienced appropriate ICD therapy until the time of generator replacement. Methods and results This was a nationwide, multicenter retrospective study that enrolled patients who were diagnosed with BS and had an ICD implantation between January 1998 and April 2014. Appropriate ICD therapies administered for ventricular tachyarrhythmia were evaluated during follow-up. A total of 117 patients (age 43 ± 12 years, male 115 [98.3%]) were enrolled, and the mean follow-up duration was 6.0 ± 4.1 years. Thirty-seven (31.6%) patients had experienced appropriate ICD therapy during follow-up. Of all patients, 46 underwent replacement of the device. After the first generator replacement, the incidence of appropriate ICD therapy remained as high as 65.2% in patients who previously experienced appropriate ICD therapy before generator replacement. In 30 patients who did not experience any cardiac events until the first generator change, two (8.7%) had an episode of appropriate ICD therapy afterwards. Conclusions No episode of ICD therapy before generator replacement could not guarantee a safe clinical course. ICD generator replacement should be considered even in patients without ICD therapy before. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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