دورية أكاديمية

Analysis of aluminum, minerals and trace elements in the milk samples from lactating mothers in Hamadan, Iran.

التفاصيل البيبلوغرافية
العنوان: Analysis of aluminum, minerals and trace elements in the milk samples from lactating mothers in Hamadan, Iran.
المؤلفون: Taravati Javad, Masoumeh, Vahidinia, Aliasghar, Samiee, Fateme, Elaridi, Jomana, Leili, Mostafa, Faradmal, Javad, Rahmani, Alireza
المصدر: Journal of Trace Elements in Medicine & Biology; Dec2018, Vol. 50, p8-15, 8p
مصطلحات موضوعية: MICRONUTRIENTS, COMPOSITION of breast milk, ALUMINUM in the body, ZINC deficiency diseases
مصطلحات جغرافية: HAMADAN (Iran)
مستخلص: Highlights • This is first to examine the minerals and aluminum contents of breast milk in West of Iran. • High levels of aluminum observed in the breast milk of 95% of participants. • The concentration of Al is extremely high compared to other studies. • Hazard quotient (HQ) of Al for 98% of the infants were obtained <1. • Zn deficiency was observed in the 50% mother's milk samples. Abstract The present cross-sectional study is aimed at analyzing the breast milk of lactating mothers in Hamadan, Iran for aluminum and several minerals and trace elements. Ten governmental health care centers were utilized to facilitate collection of breast milk samples. The breast milk samples were collected at 1, 2, 6, 7, and 12 months postpartum from one hundred healthy lactating women, who delivered full-term newborns. Detection of sodium (Na), zinc (Zn), calcium (Ca), iron (Fe), copper (Cu), magnesium (Mg) and aluminum (Al) levels was conducted with the use of Inductively Coupled Plasma Mass Spectrometry (ICP-MS). This method has shown high accuracy, precision, sensitivity, and linearity for the wide range of concentrations. The accumulated data were not normally distributed; thus, the non-parametric Mann-Whitney U test was used in the statistical analysis of the results. Mean concentrations of Fe, Zn, Cu, Ca, Mg, and Na were 0.75, 1.38, 0.35, 255, 34.58, and 155.72 μg/mL, respectively. The mean level of Al, a well-known neurotoxic metal, was determined to be an alarming 0.191 μg/mL. Moreover, 95% of participants contained very harmful concentrations of Al in their milk. This study also revealed Zn deficiency in about 50% of milk samples. Further investigation is needed to elucidate sources of exposure and factors that may influence maternal and fetal exposure to aluminum. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Supplemental Index
الوصف
تدمد:0946672X
DOI:10.1016/j.jtemb.2018.05.016