Nationwide compliance with a multidisciplinary guideline on pancreatic cancer during 6-year follow-up
| العنوان: | Nationwide compliance with a multidisciplinary guideline on pancreatic cancer during 6-year follow-up |
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| المؤلفون: | Tara M. Mackay, Judith de Vos-Geelen, Anouk E J Latenstein, Ignace H. J. T. de Hingh, Bert A. Bonsing, Johanna W. Wilmink, Lydia G. M. van der Geest, Olivier R. Busch, Marjolein Y.V. Homs, Casper H.J. van Eijck, Hjalmar C. van Santvoort, I. Quintus Molenaar, Marc G. Besselink, Hanneke W. M. van Laarhoven, Jeanin E. van Hooft, Bas Groot Koerkamp, Marco J. Bruno, Martijn W J Stommel |
| المساهمون: | Gastroenterology & Hepatology, Surgery, Medical Oncology, Graduate School, CCA - Cancer Treatment and Quality of Life, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Gastroenterology and Hepatology, Oncology, CCA -Cancer Center Amsterdam, Interne Geneeskunde, MUMC+: MA Medische Oncologie (9), RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy |
| المصدر: | Pancreatology, 20, 8, pp. 1723-1731 Pancreatology, 20(8), 1723-1731. Elsevier Pancreatology, 20, 1723-1731 Pancreatology, 20(8), 1723-1731. S. Karger AG Pancreatology, 20(8). ELSEVIER |
| بيانات النشر: | Elsevier, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Change over time, medicine.medical_specialty, ENHANCED RECOVERY, SURGERY, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Disease, PREOPERATIVE BILIARY DRAINAGE, Guideline, 03 medical and health sciences, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], ADJUVANT CHEMOTHERAPY, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Multidisciplinary approach, Pancreatic cancer, medicine, FAILURE, Humans, Netherlands, Chemotherapy, Hepatology, business.industry, General surgery, Gastroenterology, Guideline compliance, CARE, medicine.disease, Cancer registry, Management, FOLFIRINOX, Pancreatic Neoplasms, GEMCITABINE, Chemotherapy, Adjuvant, 030220 oncology & carcinogenesis, PANCREATICODUODENECTOMY, 030211 gastroenterology & hepatology, Guideline Adherence, business, Follow-Up Studies, Compliance |
| الوصف: | Background: Compliance with national guidelines on pancreatic cancer management could improve patient outcomes. Early compliance with the Dutch guideline was poor. The aim was to assess compliance with this guideline during six years after publication.Materials and methods: Nationwide guideline compliance was investigated for three subsequent time periods (2012-2013 vs. 2014-2015 vs. 2016-2017) in patients with pancreatic cancer using five quality indicators in the Netherlands Cancer Registry: 1) discussion in multidisciplinary team meeting (MDT), 2) maximum 3-week interval from final MDT to start of treatment, 3) preoperative biliary drainage when bilirubin >250 mu mol/L, 4) use of adjuvant chemotherapy, and 5) chemotherapy for inoperable disease (non-metastatic and metastatic).Results: In total, 14 491 patients were included of whom 2290 (15.8%) underwent resection and 4561 (31.5%) received chemotherapy. Most quality indicators did not change over time: overall, 88.8% of patients treated with curative intent were discussed in a MDT, 42.7% were treated with curative intent within the 3-week interval, 62.7% with a resectable head tumor and bilirubin >250 mu mol/L underwent preoperative biliary drainage, 57.2% received chemotherapy after resection, and 36.6% with metastatic disease received chemotherapy. Only use of chemotherapy for non-metastatic, non-resected disease improved over time (23.4% vs. 25.6% vs. 29.7%).Conclusion: Nationwide compliance to five quality indicators for the guideline on pancreatic cancer management showed little to no improvement during six years after publication. Besides critical review of the current quality indicators, these outcomes may suggest that a nationwide implementation program is required to increase compliance to guideline recommendations. (C) 2020 IAP and EPC. Published by Elsevier B.V. All rights reserved. |
| اللغة: | English |
| تدمد: | 1424-3911 1424-3903 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55f85485da1891dd3e0c53ef622b7d3Test https://doi.org/10.1016/j.pan.2020.10.032Test |
| حقوق: | RESTRICTED |
| رقم الانضمام: | edsair.doi.dedup.....d55f85485da1891dd3e0c53ef622b7d3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14243911 14243903 |
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