دورية أكاديمية
Hierarchical porous calcium carbonate microspheres as drug delivery vector
| العنوان: | Hierarchical porous calcium carbonate microspheres as drug delivery vector |
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| المؤلفون: | Hui Yang, Yunfeng Wang, Tongxiang Liang, Yiqun Deng, Xiaopeng Qi, Honghui Jiang, Yangjun Wu, Huichang Gao |
| المصدر: | Progress in Natural Science: Materials International, Vol 27, Iss 6, Pp 674-677 (2017) |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2017 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Calcium carbonate, Microspheres, Phase transformation, Morphology-controlled growth, Biomedical application, Materials of engineering and construction. Mechanics of materials, TA401-492 |
| الوصف: | CaCO3 crystals with different hierarchical structure were fabricated by the precipitation of CaCO3 in an aqueous solution containing guar gum (GG). Through adjusting a range of parameters, the size distribution and micro-structure of CaCO3 were well controlled. Results showed that GG facilitated the formation of the hierarchical hollow sphere through assembling of nanocrystals, while inhibited the growth of CaCO3 crystals and restrained phase transition from calcite to vaterite at high concentration of GG (CGG) condition; Moreover, increasing reaction temperature led to larger particles and stable crystalline phase formed. According to the results, a morphology map was presented. Furthermore, Drug loading and releasing results ensured porous CaCO3 microspheres a promising vector for drug delivery. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1002-0071 |
| العلاقة: | http://www.sciencedirect.com/science/article/pii/S1002007117308006Test; https://doaj.org/toc/1002-0071Test; https://doaj.org/article/e836640e826c476a9fe70ea04d8848d7Test |
| DOI: | 10.1016/j.pnsc.2017.11.005 |
| الإتاحة: | https://doi.org/10.1016/j.pnsc.2017.11.005Test https://doaj.org/article/e836640e826c476a9fe70ea04d8848d7Test |
| رقم الانضمام: | edsbas.45F18BEF |
| قاعدة البيانات: | BASE |
| تدمد: | 10020071 |
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| DOI: | 10.1016/j.pnsc.2017.11.005 |