المؤلفون: Naoki Minami, Hisanori Horiuchi, Kohei Wagatsuma, Daisuke Hirayama, Ryutaro Shirakawa, Tomoya Iida, Seiichi Hirota, Hiroki Ikeuchi, Minoru Matsuura, Hiroshi Nakase, Kentaro Kawakami, Masanori Nojima, Kanna Nagaishi

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 2, Pp 277-293 (2020)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, Th, T-helper cell, STAT3, signal transducer and activator of transcription 3, Inflammasomes, medicine.medical_treatment, medicine.disease_cause, chemistry.chemical_compound, 0302 clinical medicine, AOM, azoxymethane, GTPase, guanosine triphosphatase, TNF-α, tumor necrosis factor α, WT-T, tumors of wild-type mice, Original Research, IBD, inflammatory bowel disease, Dextran Sulfate, Gastroenterology, Colitis, mRNA, messenger RNA, SM, submucosal, MMP, matrix metalloproteinase, Real-time polymerase chain reaction, WB, Western blot, qPCR, quantitative polymerase chain reaction, RalGAP, Ral guanosine triphosphatase–activating protein, 030211 gastroenterology & hepatology, ASC, apoptosis associated speck-like protein containing a CARD, animal structures, WT-N, normal colon tissues of wild-type mice, CAC, colitis-associated cancer, Intraperitoneal injection, Guanosine, NF-κB, nuclear factor-κB, Down-Regulation, 03 medical and health sciences, Downregulation and upregulation, DSS, dextran sulfate sodium, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Humans, lcsh:RC799-869, KD, knockdown, KO-N, normal colon tissues of RalGAPα2 knockout mice, KO, knockout, Hepatology, Azoxymethane, KO-T, tumors of RalGAPα2 knockout mice, Molecular biology, WT, wild-type, IL, interleukin, Ral, 030104 developmental biology, chemistry, Apoptosis, siRNA, small interfering RNA, Colitis-Associated Cancer, Triphosphatase, lcsh:Diseases of the digestive system. Gastroenterology, NLRP3 Inflammasome, Carcinogenesis, Ral-GTPase Activating Protein (RalGAP)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d16d8f812582cc3f7b9947159562783Test
http://www.sciencedirect.com/science/article/pii/S2352345X19301390Test

المؤلفون: Iulia Oancea, Andy Wu, Michael A. McGuckin, Sumaira Z. Hasnain, Rabina Giri, John D. Hooper, Veronika Schreiber, Brett C McWhinney, Julie M. Davies, Jakob Begun, Yonghua Sheng, David P. Fairlie, Saleh Y. Alabbas, Gregor Kijanka, Yaowu He, Ramya Movva, Andrew J. Lucke, Timothy H. Florin

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 33-53 (2021)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: rac1 GTP-Binding Protein, 0301 basic medicine, TGTP, thioguanine nucleotide triphosphate, TCF/LEF, T-cell factor/lymphoid enhancer factor, Colorectal cancer, MP, mercaptopurine, TGN, thioguanine nucleotides, medicine.disease_cause, Autophagy-Related Protein 7, Inflammatory bowel disease, BrdU, bromodeoxyuridine, Mice, chemistry.chemical_compound, AOM, azoxymethane, 0302 clinical medicine, GTP, guanosine triphosphate, GTPase, guanosine triphosphatase, DSS, dextran sodium sulfate, Intestinal Mucosa, Wnt Signaling Pathway, beta Catenin, Original Research, GDP, guanosine diphosphate, IBD, inflammatory bowel disease, Colon Cancer, Mercaptopurine, Dextran Sulfate, Gastroenterology, Wnt signaling pathway, Colitis, Atg7ΔIEC, intestinal epithelial cell–specific deletion of autophagy related 7 gene, Editorial, Gene Knockdown Techniques, CRC, colorectal cancer, 030211 gastroenterology & hepatology, Colon, β-Catenin, CAC, colitis-associated cancer, Azoxymethane, Mice, Transgenic, DAI, disease activity index scores, IMPDH, inosine-5′-monophosphate dehydrogenase, 03 medical and health sciences, Administration, Rectal, Anseriformes, medicine, Autophagy, Animals, Humans, lcsh:RC799-869, Thioguanine, IC50, inhibitory concentration of 50%, Hepatology, business.industry, Neuropeptides, Cancer, DMEM, Dulbecco modified Eagle medium, PBS-T, phosphate-buffered saline with 0.1% Tween-20, HCT116 Cells, medicine.disease, WT, wild-type, TG, thioguanine, 030104 developmental biology, chemistry, siRNA, small interfering RNA, Cancer research, BSA, bovine serum albumin, lcsh:Diseases of the digestive system. Gastroenterology, Caco-2 Cells, Colitis-Associated Neoplasms, business, Carcinogenesis, HPRT, hypoxanthine phosphoribosyltransferase gene

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f601ccce23a182b6171ce5a7c5598ecTest
http://www.sciencedirect.com/science/article/pii/S2352345X20300886Test

المؤلفون: Luigi Ricciardiello, Giulia Piazzi, Chiara Alquati, Anna Prossomariti

المساهمون: Prossomariti A., Piazzi G., Alquati C., Ricciardiello L.

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 491-506 (2020)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, Colorectal cancer, Wnt/β-Catenin, Resistance, FZD, frizzled, mTORC1, Review, PI3K, phosphatidylinositol-3-kinase, DEPTOR, DEP domain-containing mTOR-interacting protein, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, GTPase, guanosine triphosphatase, Antineoplastic Combined Chemotherapy Protocols, Crosstalk, beta Catenin, Phosphoinositide-3 Kinase Inhibitors, Kinase, Gastroenterology, Wnt signaling pathway, mTORC1, mammalian target of rapamycin complex 1, APC, adenomatous polyposis coli, eIF4E, eukaryotic translation initiation factor 4E, FOXO3A, Forkhead box O3A, MNK, Mitogen-activated Protein kinase interacting kinases, Gene Expression Regulation, Neoplastic, Crosstalk (biology), PI3K/AKT/mTORC1, CRC, colorectal cancer, PORCN, Porcupine, 030211 gastroenterology & hepatology, Colorectal Neoplasms, RAS, Rat Sarcoma, Signal Transduction, Rheb, ras homolog enriched in brain, TSC, tuberous sclerosis, 4E-BP1, 4E binding protein 1, mTOR, mammalian target of rapamycin, RNF43, ring finger protein 43, Biology, Mechanistic Target of Rapamycin Complex 1, TNKSi, tankyrase inhibitors, AKT, protein kinase B, 03 medical and health sciences, eEF2K, elongation factor 2 kinase, MEK, Mitogen-activated protein kinase kinase, Cell Line, Tumor, medicine, GSK3, glycogen synthase kinase 3, Animals, Humans, FAP, familial adenomatous polyposis, lcsh:RC799-869, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, TNKS, tankyrase, Colorectal Cancer, Hepatology, ZNRF3, zinc/ring finger 3, medicine.disease, YAP, Yes-associated protein, EGFR, epidermal growth factor receptor, Wnt Proteins, Disease Models, Animal, 030104 developmental biology, DVL, Dishevelled, Drug Resistance, Neoplasm, Catenin, Cancer research, lcsh:Diseases of the digestive system. Gastroenterology, Proto-Oncogene Proteins c-akt, LRP, low-density lipoprotein receptors 5 and 6, S6K, S6 Kinase

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7a306ac692719a8347e0c547725351Test
http://www.sciencedirect.com/science/article/pii/S2352345X20300515Test

المؤلفون: Phasha, Mmatshepho Malekgale, Wingfield, Michael J., Wingfield, Brenda D., Coetzee, Martin Petrus Albertus, Hallen-Adams, H., Fru, Felix Fon, Swalarsk-Parry, Benedicta S., Yilmaz, Neriman, Duong, Tuan A., Steenkamp, Emma Theodora

مصطلحات موضوعية: Ras2 gene, Guanosine triphosphatase (GTPase), Signaling, Pathogenicity, Fusarium circinatum, Pinus patula

العلاقة: http://hdl.handle.net/2263/80254Test; Phasha, M.M., Wingfield, M.J., Wingfield, B.D. et al. 2021, 'Ras2 is important for growth and pathogenicity in Fusarium circinatum', Fungal Genetics and Biology, vol. 150, art. 103541, pp. 1-10.; 1087-1845 (print); 1096-0937 (online)

الإتاحة: https://doi.org/10.1016/j.fgb.2021.103541Test
http://hdl.handle.net/2263/80254Test

المؤلفون: Brandon K. Fornwalt, Erhe Gao, Bryana R. Levitan, Christopher M. Haggerty, Jonathan Satin, Prabhakara R Nagareddy, Janet R. Manning, Catherine N. Withers, Ahmed Abdel-Latif, Lakshman Chelvarajan, Himi Tripathi, Douglas A. Andres

المصدر: JACC: Basic to Translational Science, Vol 3, Iss 1, Pp 83-96 (2018)
JACC: Basic to Translational Science

مصطلحات موضوعية: 0301 basic medicine, Inotrope, medicine.medical_specialty, Cardiac output, lcsh:Diseases of the circulatory (Cardiovascular) system, Inflammation, GTPase, 030204 cardiovascular system & hematology, Contractility, PRECLINICAL RESEARCH, 03 medical and health sciences, PCR, polymerase chain reaction, 0302 clinical medicine, GTPase, guanosine triphosphatase, Internal medicine, medicine, EF, ejection fraction, Myocardial infarction, HFrEF, heart failure with reduced ejection fraction, Cardioprotection, business.industry, Calcium channel, medicine.disease, WT, wild-type, LTCC, L-type calcium channel complex, eye diseases, AMI, acute myocardial infarction, LAD, left anterior descending coronary artery, 030104 developmental biology, myocardial infarction, inflammation, lcsh:RC666-701, cardioprotection, MI, myocardial infarction, RNA, ribonucleic acid, Cardiology, calcium channel, medicine.symptom, Cardiology and Cardiovascular Medicine, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2afb07219af2b9f2bb17a928ba4255c1Test
http://www.sciencedirect.com/science/article/pii/S2452302X17302267Test

المؤلفون: Kim E. Barrett

المصدر: Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: Mitochondrial Dynamics, Bacterial Adhesion, EPEC, enteropathogenic E coli, GTPase, guanosine triphosphatase, Crohn Disease, Medicine, Intestinal Mucosa, Original Research, Crohn's disease, Fis1, fission protein-1, IBD, inflammatory bowel disease, Drp1, dynamin-related peptide 1, PGC-1α, peroxisome proliferator-activated receptor γ coactivator 1α, Gastroenterology, Mitochondria, Editorial, Caspase-3, Gene Knockdown Techniques, Host-Pathogen Interactions, AIF, apoptosis inducing factor, Epithelial Permeability, Dynamins, ATP, adenosine triphosphate, Colon, MEDLINE, Drp1, Permeability, CCCP, carbonyl cyanide m-chlorophenyl hydrazone, ROS, reactive oxygen species, Text mining, Cell Line, Tumor, Escherichia coli, Humans, TER, transepithelial resistance, Mitochondrial Fission and Fusion, Bacteria, OPA1, optic atrophy factor 1, Hepatology, business.industry, Gene Expression Profiling, Human Epithelial Cell Lines, Epithelial Cells, medicine.disease, CFU, colony forming unit, IL, interleukin, Gene Expression Regulation, siRNA, small interfering RNA, Immunology, business, AIEC, adherent invasive Escherichia coli

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b93a2d7cc23500777e0bf52617aa3632Test
http://europepmc.org/articles/PMC7846483Test

المؤلفون: Berthold, Jessica, Schenkova, Kristína, Ramos, Sonia, Miura, Yoshie, Furukawa, Manabu, Aspenstrom, Pontus, Rivero, Francisco

المساهمون: German Research Foundation, Fundación Ramón Areces, University of Cologne, Swedish Research Council, National Cancer Institute (US), National Institutes of Health (US)

مصطلحات موضوعية: Cancer profiling array, Cullin, Ubiquitin, BTB domain, RhoBTB, Rho guanosine triphosphatase

العلاقة: Postprint; https://doi.org/10.1016/j.yexcr.2008.09.005Test; Experimental Cell Research 314(19): 3453-3465 (2008); http://hdl.handle.net/10261/93436Test; http://dx.doi.org/10.13039/100008054Test; http://dx.doi.org/10.13039/100000002Test; http://dx.doi.org/10.13039/501100008001Test; http://dx.doi.org/10.13039/501100001659Test

الإتاحة: https://doi.org/10.1016/j.yexcr.2008.09.005Test
https://doi.org/10.13039/100008054Test
https://doi.org/10.13039/100000002Test
https://doi.org/10.13039/501100008001Test
https://doi.org/10.13039/501100001659Test
http://hdl.handle.net/10261/93436Test

المؤلفون: Lee A. Denson

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 2, Pp 426-427 (2020)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: ATP, adenosine triphosphate, macrophage, Mitochondrial Dynamics, IEC, intestinal epithelial cell, TER, transepithelial electrical resistance, ROS, reactive oxygen species, GTPase, guanosine triphosphatase, DNBS, medicine, Humans, DSS, dextran sodium sulfate, MFN, mitofusin, Fis1, mitochondrial fission protein-1, Colitis, lcsh:RC799-869, Original Research, DSS, TNF, tumor necrosis factor, IBD, inflammatory bowel disease, OPA1, optic atrophy factor 1, Hepatology, business.industry, Gastroenterology, DNBS, di-nitrobenzene sulfonic acid, medicine.disease, Mitochondria, IL, interleukin, inflammation, Drp1, dynamin related protein-1, Cancer research, LPS, lipopolysaccharide, qPCR, quantitative polymerase chain reaction, lcsh:Diseases of the digestive system. Gastroenterology, epithelium, GM-CSF, granulocyte-macrophage colony-stimulating factor, business, TUNEL, deoxyuride-5′-triphosphate biotin nick end labeling

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bfbc0a62ca07f7cce53f7ceaf2eb4e9Test
http://www.sciencedirect.com/science/article/pii/S2352345X20300849Test

المؤلفون: Kristína Schenková, Francisco Rivero, Manabu Furukawa, Yoshie Miura, Jessica Berthold, Pontus Aspenström, Sonia Ramos

المساهمون: German Research Foundation, Fundación Ramón Areces, University of Cologne, Swedish Research Council, National Cancer Institute (US), National Institutes of Health (US)

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: rho GTP-Binding Proteins, Proteasome Endopeptidase Complex, Ubiquitin-Protein Ligases, Rho guanosine triphosphatase, GTPase, Biology, Models, Biological, Article, Cancer profiling array, Cullin, Mice, Prenylation, Ubiquitin, Chlorocebus aethiops, Tumor Cells, Cultured, Animals, Homeostasis, Humans, BTB domain, RhoBTB, Microscopy, Confocal, Cullin Proteins, Cell Biology, Ubiquitin ligase, Cell biology, COS Cells, biology.protein, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76972eb1f2f90e9451121571b6014951Test
http://hdl.handle.net/10261/93436Test

المؤلفون: Ramos, Sonia, Kadhemi, Farshad, Somesh, Baggavalli P., Rivero, Francisco

المساهمون: Fundación Ramón Areces, German Research Foundation, University of Cologne

مصطلحات موضوعية: Cancer, BTB domain, Signal transduction, Cytoskeleton, Rho guanosine triphosphatase, Expression pattern

العلاقة: No; e-issn: 1879-0038; Gene 298(2): 147-157 (2002); http://hdl.handle.net/10261/191403Test; http://dx.doi.org/10.13039/100008054Test; http://dx.doi.org/10.13039/501100001659Test; http://dx.doi.org/10.13039/501100008001Test

الإتاحة: https://doi.org/10.1016/S0378-1119Test(02)00980-0
https://doi.org/10.13039/100008054Test
https://doi.org/10.13039/501100001659Test
https://doi.org/10.13039/501100008001Test
http://hdl.handle.net/10261/191403Test