Eosinophils depletion therapy for severe asthma management following favorable response to mepolizumab
| العنوان: | Eosinophils depletion therapy for severe asthma management following favorable response to mepolizumab |
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| المؤلفون: | Seijiro Minamoto, Osamu Matsuno |
| المصدر: | Respiratory Medicine Case Reports Respiratory Medicine Case Reports, Vol 28, Iss, Pp-(2019) |
| بيانات النشر: | Elsevier, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Pulmonary and Respiratory Medicine, Severe asthma, Case Report, macromolecular substances, Eosinophil, BT, bronchial thermoplasty, 03 medical and health sciences, chemistry.chemical_compound, FAVORABLE RESPONSE, LABA, long-acting beta-agonist, 0302 clinical medicine, FeNO, fraction of exhaled nitric oxide, FVC - Forced vital capacity, Medicine, LTRA, leukotriene antagonist, Mepolizumab, lcsh:RC705-779, business.industry, Asthma symptoms, lcsh:Diseases of the respiratory system, Benralizumab, ICS, inhaled corticosteroids, ACT, Asthma control test, respiratory tract diseases, CT, computed tomography, medicine.anatomical_structure, LAMA, long-acting muscarinic antagonist, 030228 respiratory system, chemistry, 030220 oncology & carcinogenesis, Immunology, FVC, forced vital capacity, FEV1, expiratory volume in 1 second, business, medicine.drug |
| الوصف: | We described three severe asthmatics whose asthma symptoms were rapidly improved by benralizumab following favorable response to mepolizumab. Benralizumab-induced eosinophil depletion contributed to clinical improvement of severe asthma after mepolizumab-induced eosinophil reduction; thus, prior favorable responses to mepolizumab may predict benralizumab efficacy. Keywords: Benralizumab, Mepolizumab, Severe asthma, Eosinophil |
| اللغة: | English |
| تدمد: | 2213-0071 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4c679c8748f637452569268c870d10Test http://europepmc.org/articles/PMC6630060Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....0b4c679c8748f637452569268c870d10 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22130071 |
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