Exploring treatment preferences facilitated recruitment to randomized controlled trials
| العنوان: | Exploring treatment preferences facilitated recruitment to randomized controlled trials |
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| المؤلفون: | J A Lane, Jenny L Donovan, Julia Wade, Freddie C. Hamdy, David E. Neal, Nicola Mills |
| المصدر: | Journal of Clinical Epidemiology |
| بيانات النشر: | Elsevier, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Treatment preferences, Male, medicine.medical_specialty, Epidemiology, Decision Making, MEDLINE, Alternative medicine, ProtecT study, law.invention, 03 medical and health sciences, 0302 clinical medicine, Qualitative analysis, Randomized controlled trial, law, Informed consent, medicine, Humans, Multicenter Studies as Topic, 030212 general & internal medicine, Information exchange, Aged, Randomized Controlled Trials as Topic, Prostate cancer, Informed Consent, business.industry, 030503 health policy & services, Patient Selection, Prostatic Neoplasms, Patient Preference, Middle Aged, Preference, 3. Good health, Family medicine, Physical therapy, Recruitment to RCTs, Original Article, Qualitative research methods, 0305 other medical science, business, Qualitative research |
| الوصف: | Objective: To explore how patients' treatment preferences were expressed and justified during recruitment to a randomized controlled trial (RCT) and how they influenced participation and treatment decisions. Study Design and Setting: Qualitative analysis of audio recordings of recruitment appointments with 93 participants aged 51-70 years in a UK multicenter RCT of localized prostate cancer treatments. Results: Treatment preferences at recruitment were more complex and dynamic than previously assumed. Most participants expressed views about treatments early in appointments, ranging on a continuum from hesitant to well-formed opinions. As recruiters elicited men's views and provided detailed evidence-based treatment and study information, some opted for their preference, but many became uncertain and open to RCT recruitment, often accepting a different treatment from their original "preference." Discussion of treatment preferences did not act as the expected barrier to recruitment but actively enabled many to express their concerns and reach an informed decision that often included RCT participation. Conclusion: Exploring treatment preferences and providing evidence-based information can improve levels of informed decision making and facilitate RCT participation. Treatment preferences should be reconceptualized from a barrier to recruitment to an integral part of the information exchange necessary for informed decision making about treatments and RCT participation. © 2011 Elsevier Inc. All rights reserved. |
| اللغة: | English |
| تدمد: | 1878-5921 0895-4356 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5b7c40831fd25ed5778b223b3e07d6Test http://europepmc.org/articles/PMC3167372Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6b5b7c40831fd25ed5778b223b3e07d6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18785921 08954356 |
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